Search Results - "So, Peter T. C"

High Resolution Live Cell Raman Imaging Using Subcellular Organelle-Targeting SERS-Sensitive Gold Nanoparticles with Highly Narrow Intra-Nanogap by Kang, Jeon Woong, So, Peter T. C, Dasari, Ramachandra R, Lim, Dong-Kwon

“…We report a method to achieve high speed and high resolution live cell Raman images using small spherical gold nanoparticles with highly narrow intra-nanogap…”
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Multiline orthogonal scanning temporal focusing (mosTF) microscopy for scattering reduction in in vivo brain imaging by Xue, Yi, Boivin, Josiah R., Wadduwage, Dushan N., Park, Jong Kang, Nedivi, Elly, So, Peter T. C.

“…Temporal focusing two-photon microscopy has been utilized for high-resolution imaging of neuronal and synaptic structures across volumes spanning hundreds of…”
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Chip-Based Resonance Raman Spectroscopy Using Tantalum Pentoxide Waveguides by Coucheron, David A., Wadduwage, Dushan N., Murugan, G. Senthil, So, Peter T. C., Ahluwalia, Balpreet S.

“…Blood analysis is an important diagnostic tool, as it provides a wealth of information about the patient's health. Raman spectroscopy is a promising tool for…”
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Label-free three-photon imaging of intact human cerebral organoids for tracking early events in brain development and deficits in Rett syndrome by Yildirim, Murat, Delepine, Chloe, Feldman, Danielle, Pham, Vincent A, Chou, Stephanie, Ip, Jacque, Nott, Alexi, Tsai, Li-Huei, Ming, Guo-Li, So, Peter T C, Sur, Mriganka

“…Human cerebral organoids are unique in their development of progenitor-rich zones akin to ventricular zones from which neuronal progenitors differentiate and…”
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Clustered Dynamics of Inhibitory Synapses and Dendritic Spines in the Adult Neocortex by Chen, Jerry L., Villa, Katherine L., Cha, Jae Won, So, Peter T.C., Kubota, Yoshiyuki, Nedivi, Elly

“…A key feature of the mammalian brain is its capacity to adapt in response to experience, in part by remodeling of synaptic connections between neurons…”
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DEEP-squared: deep learning powered De-scattering with Excitation Patterning by Wijethilake, Navodini, Anandakumar, Mithunjha, Zheng, Cheng, So, Peter T. C., Yildirim, Murat, Wadduwage, Dushan N.

“…Limited throughput is a key challenge in in vivo deep tissue imaging using nonlinear optical microscopy. Point scanning multiphoton microscopy, the current…”
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Mapping nanoscale topographic features in thick tissues with speckle diffraction tomography by Kang, Sungsam, Zhou, Renjie, Brelen, Marten, Mak, Heather K., Lin, Yuechuan, So, Peter T. C., Yaqoob, Zahid

“…Resolving three-dimensional morphological features in thick specimens remains a significant challenge for label-free imaging. We report a new speckle…”
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Virtual k-Space Modulation Optical Microscopy by Kuang, Cuifang, Ma, Ye, Zhou, Renjie, Zheng, Guoan, Fang, Yue, Xu, Yingke, Liu, Xu, So, Peter T C

“…We report a novel superresolution microscopy approach for imaging fluorescence samples. The reported approach, termed virtual k-space modulation optical…”
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Optical Diffraction Tomography and Raman Confocal Microscopy for the Investigation of Vacuoles Associated with Cancer Senescent Engulfing Cells by Ghislanzoni, Silvia, Kang, Jeon Woong, Bresci, Arianna, Masella, Andrea, Kobayashi-Kirschvink, Koseki J, Polli, Dario, Bongarzone, Italia, So, Peter T C

“…Wild-type p53 cancer therapy-induced senescent cells frequently engulf and degrade neighboring ones inside a massive vacuole in their cytoplasm. After…”
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High-throughput three-dimensional lithographic microfabrication by Kim, Daekeun, So, Peter T C

“…A 3D lithographic microfabrication process has been developed that is high throughput, scalable, and capable of producing arbitrary patterns. It offers the…”
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Functional imaging of visual cortical layers and subplate in awake mice with optimized three-photon microscopy by Yildirim, Murat, Sugihara, Hiroki, So, Peter T. C., Sur, Mriganka

“…Two-photon microscopy is used to image neuronal activity, but has severe limitations for studying deeper cortical layers. Here, we developed a custom…”
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Label-free morpho-molecular phenotyping of living cancer cells by combined Raman spectroscopy and phase tomography by Bresci, Arianna, Kobayashi-Kirschvink, Koseki J., Cerullo, Giulio, Vanna, Renzo, So, Peter T. C., Polli, Dario, Kang, Jeon Woong

“…Accurate, rapid and non-invasive cancer cell phenotyping is a pressing concern across the life sciences, as standard immuno-chemical imaging and omics require…”
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Eleven quick tips for running an interdisciplinary short course for new graduate students by Saunders, Timothy E, He, Cynthia Y, Koehl, Patrice, Ong, L L Sharon, So, Peter T C

“…Quantitative reasoning and techniques are increasingly ubiquitous across the life sciences. However, new graduate researchers with a biology background are…”
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Rosa26-GFP direct repeat (RaDR-GFP) mice reveal tissue- and age-dependence of homologous recombination in mammals in vivo by Sukup-Jackson, Michelle R, Kiraly, Orsolya, Kay, Jennifer E, Na, Li, Rowland, Elizabeth A, Winther, Kelly E, Chow, Danielle N, Kimoto, Takafumi, Matsuguchi, Tetsuya, Jonnalagadda, Vidya S, Maklakova, Vilena I, Singh, Vijay R, Wadduwage, Dushan N, Rajapakse, Jagath, So, Peter T C, Collier, Lara S, Engelward, Bevin P

“…Homologous recombination (HR) is critical for the repair of double strand breaks and broken replication forks. Although HR is mostly error free, inherent or…”
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Quantification of liver fibrosis via second harmonic imaging of the Glisson's capsule from liver surface by Xu, Shuoyu, Kang, Chiang Huen, Gou, Xiaoli, Peng, Qiwen, Yan, Jie, Zhuo, Shuangmu, Cheng, Chee Leong, He, Yuting, Kang, Yuzhan, Xia, Wuzheng, So, Peter T. C., Welsch, Roy, Rajapakse, Jagath C., Yu, Hanry

“…Liver surface is covered by a collagenous layer called the Glisson's capsule. The structure of the Glisson's capsule is barely seen in the biopsy samples for…”
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In Situ Quantification of Surface Chemistry in Porous Collagen Biomaterials by Tzeranis, Dimitrios S., Soller, Eric C., Buydash, Melissa C., So, Peter T. C., Yannas, Ioannis V.

“…Cells inside a 3D matrix (such as tissue extracellular matrix or biomaterials) sense their insoluble environment through specific binding interactions between…”
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Fibro-C-Index: comprehensive, morphology-based quantification of liver fibrosis using second harmonic generation and two-photon microscopy by Tai, Dean C. S, Tan, Nancy, Xu, Shuoyu, Kang, Chiang Huen, Chia, Ser Mien, Cheng, Chee Leong, Wee, Aileen, Wei, Chiang Li, Raja, Anju Mythreyi, Xiao, Guangfa, Chang, Shi, Rajapakse, Jagath C, So, Peter T. C, Tang, Hui-Huan, Chen, Chien Shing, Yu, Hanry

“…We develop a standardized, fully automated, quantification system for liver fibrosis assessment using second harmonic generation microscopy and a…”
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Absorption by water increases fluorescence image contrast of biological tissue in the shortwave infrared by Carr, Jessica A., Aellen, Marianne, Franke, Daniel, So, Peter T. C., Bruns, Oliver T., Bawendi, Moungi G.

“…Recent technology developments have expanded the wavelength window for biological fluorescence imaging into the shortwave infrared. We show here a mechanistic…”
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Multiphoton Autofluorescence and Second-Harmonic Generation Imaging of the Ex Vivo Porcine Eye by Teng, Shu-Wen, Tan, Hsin-Yuan, Peng, Ju-Li, Lin, Huei-Hsing, Kim, Ki Hean, Lo, Wen, Sun, Yen, Lin, Wei-Chou, Lin, Sung-Jan, Jee, Shiou-Hwa, So, Peter T. C, Dong, Chen-Yuan

“…The purpose of this work was to demonstrate the use of the combined imaging modality of multiphoton autofluorescence and second-harmonic generation (SHG)…”
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Prediction of single-cell RNA expression profiles in live cells by Raman microscopy with Raman2RNA by Kobayashi-Kirschvink, Koseki J., Comiter, Charles S., Gaddam, Shreya, Joren, Taylor, Grody, Emanuelle I., Ounadjela, Johain R., Zhang, Ke, Ge, Baoliang, Kang, Jeon Woong, Xavier, Ramnik J., So, Peter T. C., Biancalani, Tommaso, Shu, Jian, Regev, Aviv

“…Single-cell RNA sequencing and other profiling assays have helped interrogate cells at unprecedented resolution and scale, but are inherently destructive…”
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