Search Results - "So, C T"

Flourishing Across Europe: Application of a New Conceptual Framework for Defining Well-Being by Huppert, Felicia A., So, Timothy T. C.

“…Governments around the world are recognising the importance of measuring subjective well-being as an indicator of progress. But how should well-being be…”
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High Resolution Live Cell Raman Imaging Using Subcellular Organelle-Targeting SERS-Sensitive Gold Nanoparticles with Highly Narrow Intra-Nanogap by Kang, Jeon Woong, So, Peter T. C, Dasari, Ramachandra R, Lim, Dong-Kwon

“…We report a method to achieve high speed and high resolution live cell Raman images using small spherical gold nanoparticles with highly narrow intra-nanogap…”
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Multiline orthogonal scanning temporal focusing (mosTF) microscopy for scattering reduction in in vivo brain imaging by Xue, Yi, Boivin, Josiah R., Wadduwage, Dushan N., Park, Jong Kang, Nedivi, Elly, So, Peter T. C.

“…Temporal focusing two-photon microscopy has been utilized for high-resolution imaging of neuronal and synaptic structures across volumes spanning hundreds of…”
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Chip-Based Resonance Raman Spectroscopy Using Tantalum Pentoxide Waveguides by Coucheron, David A., Wadduwage, Dushan N., Murugan, G. Senthil, So, Peter T. C., Ahluwalia, Balpreet S.

“…Blood analysis is an important diagnostic tool, as it provides a wealth of information about the patient's health. Raman spectroscopy is a promising tool for…”
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Label-free three-photon imaging of intact human cerebral organoids for tracking early events in brain development and deficits in Rett syndrome by Yildirim, Murat, Delepine, Chloe, Feldman, Danielle, Pham, Vincent A, Chou, Stephanie, Ip, Jacque, Nott, Alexi, Tsai, Li-Huei, Ming, Guo-Li, So, Peter T C, Sur, Mriganka

“…Human cerebral organoids are unique in their development of progenitor-rich zones akin to ventricular zones from which neuronal progenitors differentiate and…”
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High-throughput three-dimensional lithographic microfabrication by Kim, Daekeun, So, Peter T C

“…A 3D lithographic microfabrication process has been developed that is high throughput, scalable, and capable of producing arbitrary patterns. It offers the…”
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Functional imaging of visual cortical layers and subplate in awake mice with optimized three-photon microscopy by Yildirim, Murat, Sugihara, Hiroki, So, Peter T. C., Sur, Mriganka

“…Two-photon microscopy is used to image neuronal activity, but has severe limitations for studying deeper cortical layers. Here, we developed a custom…”
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DEEP-squared: deep learning powered De-scattering with Excitation Patterning by Wijethilake, Navodini, Anandakumar, Mithunjha, Zheng, Cheng, So, Peter T. C., Yildirim, Murat, Wadduwage, Dushan N.

“…Limited throughput is a key challenge in in vivo deep tissue imaging using nonlinear optical microscopy. Point scanning multiphoton microscopy, the current…”
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Mapping nanoscale topographic features in thick tissues with speckle diffraction tomography by Kang, Sungsam, Zhou, Renjie, Brelen, Marten, Mak, Heather K., Lin, Yuechuan, So, Peter T. C., Yaqoob, Zahid

“…Resolving three-dimensional morphological features in thick specimens remains a significant challenge for label-free imaging. We report a new speckle…”
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Clustered Dynamics of Inhibitory Synapses and Dendritic Spines in the Adult Neocortex by Chen, Jerry L., Villa, Katherine L., Cha, Jae Won, So, Peter T.C., Kubota, Yoshiyuki, Nedivi, Elly

“…A key feature of the mammalian brain is its capacity to adapt in response to experience, in part by remodeling of synaptic connections between neurons…”
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Virtual k-Space Modulation Optical Microscopy by Kuang, Cuifang, Ma, Ye, Zhou, Renjie, Zheng, Guoan, Fang, Yue, Xu, Yingke, Liu, Xu, So, Peter T C

“…We report a novel superresolution microscopy approach for imaging fluorescence samples. The reported approach, termed virtual k-space modulation optical…”
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Optical Diffraction Tomography and Raman Confocal Microscopy for the Investigation of Vacuoles Associated with Cancer Senescent Engulfing Cells by Ghislanzoni, Silvia, Kang, Jeon Woong, Bresci, Arianna, Masella, Andrea, Kobayashi-Kirschvink, Koseki J, Polli, Dario, Bongarzone, Italia, So, Peter T C

“…Wild-type p53 cancer therapy-induced senescent cells frequently engulf and degrade neighboring ones inside a massive vacuole in their cytoplasm. After…”
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Absorption by water increases fluorescence image contrast of biological tissue in the shortwave infrared by Carr, Jessica A., Aellen, Marianne, Franke, Daniel, So, Peter T. C., Bruns, Oliver T., Bawendi, Moungi G.

“…Recent technology developments have expanded the wavelength window for biological fluorescence imaging into the shortwave infrared. We show here a mechanistic…”
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Label-free morpho-molecular phenotyping of living cancer cells by combined Raman spectroscopy and phase tomography by Bresci, Arianna, Kobayashi-Kirschvink, Koseki J., Cerullo, Giulio, Vanna, Renzo, So, Peter T. C., Polli, Dario, Kang, Jeon Woong

“…Accurate, rapid and non-invasive cancer cell phenotyping is a pressing concern across the life sciences, as standard immuno-chemical imaging and omics require…”
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Structures and topological defects in pressure-driven lyotropic chromonic liquid crystals by Zhang, Qing, Zhang, Rui, Ge, Baoliang, Yaqoob, Zahid, So, Peter T. C., Bischofberger, Irmgard

“…Lyotropic chromonic liquid crystals are water-based materials composed of self-assembled cylindrical aggregates. Their behavior under flow is poorly…”
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Quantification of liver fibrosis via second harmonic imaging of the Glisson's capsule from liver surface by Xu, Shuoyu, Kang, Chiang Huen, Gou, Xiaoli, Peng, Qiwen, Yan, Jie, Zhuo, Shuangmu, Cheng, Chee Leong, He, Yuting, Kang, Yuzhan, Xia, Wuzheng, So, Peter T. C., Welsch, Roy, Rajapakse, Jagath C., Yu, Hanry

“…Liver surface is covered by a collagenous layer called the Glisson's capsule. The structure of the Glisson's capsule is barely seen in the biopsy samples for…”
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Deep learning enables automated scoring of liver fibrosis stages by Yu, Yang, Wang, Jiahao, Ng, Chan Way, Ma, Yukun, Mo, Shupei, Fong, Eliza Li Shan, Xing, Jiangwa, Song, Ziwei, Xie, Yufei, Si, Ke, Wee, Aileen, Welsch, Roy E., So, Peter T. C., Yu, Hanry

“…Current liver fibrosis scoring by computer-assisted image analytics is not fully automated as it requires manual preprocessing (segmentation and feature…”
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Eleven quick tips for running an interdisciplinary short course for new graduate students by Saunders, Timothy E, He, Cynthia Y, Koehl, Patrice, Ong, L L Sharon, So, Peter T C

“…Quantitative reasoning and techniques are increasingly ubiquitous across the life sciences. However, new graduate researchers with a biology background are…”
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Reference-free polarization-sensitive quantitative phase imaging using single-point optical phase conjugation by Shin, Seungwoo, Lee, KyeoReh, Yaqoob, Zahid, So, Peter T C, Park, YongKeun

“…We propose and experimentally demonstrate a method of polarization-sensitive quantitative phase imaging using two photodetectors and a digital micromirror…”
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Rosa26-GFP direct repeat (RaDR-GFP) mice reveal tissue- and age-dependence of homologous recombination in mammals in vivo by Sukup-Jackson, Michelle R, Kiraly, Orsolya, Kay, Jennifer E, Na, Li, Rowland, Elizabeth A, Winther, Kelly E, Chow, Danielle N, Kimoto, Takafumi, Matsuguchi, Tetsuya, Jonnalagadda, Vidya S, Maklakova, Vilena I, Singh, Vijay R, Wadduwage, Dushan N, Rajapakse, Jagath, So, Peter T C, Collier, Lara S, Engelward, Bevin P

“…Homologous recombination (HR) is critical for the repair of double strand breaks and broken replication forks. Although HR is mostly error free, inherent or…”
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