Search Results - "Snyder, S.H."

Pathogenic disruption of DISC1-serine racemase binding elicits schizophrenia-like behavior via D-serine depletion by Ma, T M, Abazyan, S, Abazyan, B, Nomura, J, Yang, C, Seshadri, S, Sawa, A, Snyder, S H, Pletnikov, M V

“…Perturbation of Disrupted-In-Schizophrenia-1 (DISC1) and D -serine/NMDA receptor hypofunction have both been implicated in the pathophysiology of schizophrenia…”
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d-Aspartate disposition in neuronal and endocrine tissues: ontogeny, biosynthesis and release by Wolosker, H, D’Aniello, A, Snyder, S.H

“…High levels of d-aspartate occur in the brain and endocrine glands, such as pineal, adrenal and pituitary. In the brain, d-aspartate levels are highest in…”
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P.4.019 Absence of D-serine results in abnormal dopamine–glutamate dialogue in the prefrontal cortex by Dallérac, G, Turpin, F, Sacchi, S, Levasseur, G, Rivet, J.M, Pollegioni, L, Coyle, J.T, Snyder, S.H, Millan, M.J, Mothet, J.P

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S.12.02 Absence of D-serine results in abnormal dopamine–glutamate dialogue in the prefrontal cortex by Dallerac, G, Tupin, F, Morisot, N, Levasseur, G, Sacchi, S, Fossat, P, Rivet, J.M, Oliet, S.H, Coyle, J.T, Pollegioni, L, Snyder, S.H, Contarino, A, Millan, M.J, Mothet, J.P

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Species, strain and developmental variations in hippocampal neuronal and endothelial nitric oxide synthase clarify discrepancies in nitric oxide-dependent synaptic plasticity by Blackshaw, S, Eliasson, M.J.L, Sawa, A, Watkins, C.C, Krug, D, Gupta, A, Arai, T, Ferrante, R.J, Snyder, S.H

“…Nitric oxide (NO) has been implicated in long-term potentiation (LTP) in pyramidal neurons in cellular area 1 (CA1) of the hippocampus. However, considerable…”
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Nitric oxide synthase regulatory sites. Phosphorylation by cyclic AMP-dependent protein kinase, protein kinase C, and calcium/calmodulin protein kinase; identification of flavin and calmodulin binding sites by BREDT, D. S, FERRIS, C. D, SNYDER, S. H

“…Nitric oxide (NO) is an important molecular messenger accounting for endothelial-derived relaxing activity in blood vessels, mediating cytotoxic actions of…”
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Generation of superoxide by purified brain nitric oxide synthase by Pou, S, Pou, W S, Bredt, D S, Snyder, S H, Rosen, G M

“…Brain nitric oxide synthase (NOS), which utilizes NADPH and calcium/calmodulin as cofactors for metabolizing L-arginine to nitric oxide (NO) and L-citrulline,…”
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Expression of the nitric oxide synthase gene in mouse macrophages activated for tumor cell killing. Molecular basis for the synergy between interferon-gamma and lipopolysaccharide by LORSBACH, R. B, MURPHY, W. J, LOWENSTEIN, C. J, SNYDER, S. H, RUSSELL, S. W

“…Macrophages can become activated to kill both tumor cells and a variety of microbes. Results here show that synthesis of nitric oxide (NO), a mediator of many…”
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The localization of nitric oxide synthase in the rat eye and related cranial ganglia by Yamamoto, R, Bredt, D S, Snyder, S H, Stone, R A

“…Nitric oxide synthase is the biosynthetic enzyme for the free radical neurotransmitter nitric oxide. Using an affinity-purified antiserum, nitric oxide…”
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Naturally occurring free D-aspartate is a nuclear component of cells in the mammalian hypothalamo-neurohypophyseal system by Wang, H, Wolosker, H, Morris, J.F, Pevsner, J, Snyder, S.H, Selkoe, D.J

“…It is generally believed that only L-amino acids have a physiological role in species other than bacteria. Recently, the existence of some D-amino acids,…”
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Cloning and Characterization of 4.1G (EPB41L2), a New Member of the Skeletal Protein 4.1 (EPB41) Gene Family by Parra, M., Gascard, P., Walensky, L.D., Snyder, S.H., Mohandas, N., Conboy, J.G.

“…The prototypical erythrocyte membrane skeletal protein 4.1 (HGMW-approved symbol EPB41), here designated 4.1R, is encoded by a large, complexly spliced gene…”
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Neuronal nitric oxide synthase is induced in spinal neurons by traumatic injury by Wu, W, Liuzzi, F J, Schinco, F P, Depto, A S, Li, Y, Mong, J A, Dawson, T M, Snyder, S H

“…Nitric oxide appears to mediate the immune functions of macrophages, the influence of endothelial cells on blood vessel relaxation, and also to serve as a…”
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Rat spinal cord neurons contain nitric oxide synthase by Saito, S, Kidd, G J, Trapp, B D, Dawson, T M, Bredt, D S, Wilson, D A, Traystman, R J, Snyder, S H, Hanley, D F

“…We describe the distribution and characteristics of nitric oxide synthase-containing neurons in rat spinal cord using a polyclonal affinity-purified antibody…”
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Nocturnal motor coordination deficits in neuronal nitric oxide synthase knock-out mice by Kriegsfeld, L.J., Eliasson, M.J.L., Demas, G.E., Blackshaw, S., Dawson, T.M., Nelson, R.J., Snyder, S.H.

“…Nitric oxide is formed in the brain primarily by neurons containing neuronal nitric oxide synthase (nNOS), though some neurons may express endothelial NOS…”
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The immunophilins, FK506 binding protein and cyclophilin, are discretely localized in the brain: relationship to calcineurin by Dawson, T M, Steiner, J P, Lyons, W E, Fotuhi, M, Blue, M, Snyder, S H

“…The immunosuppressant drugs cyclosporin A and FK506 bind to small, predominantly soluble proteins cyclophilin and FK506 binding protein, respectively, to…”
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Differential neuronal localizations and dynamics of phosphorylated and unphosphorylated type 1 inositol 1,4,5-trisphosphate receptors by Pieper, A.A, Brat, D.J, O’Hearn, E, Krug, D.K, Kaplin, A.I, Takahashi, K, Greenberg, J.H, Ginty, D, Molliver, M.E, Snyder, S.H

“…Type 1 inositol 1,4,5-trisphosphate receptors are phosphorylated by cyclic-AMP-dependent protein kinase A at serines 1589 and 1755, with serine 1755…”
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Antidepressant action of ketamine via mTOR is mediated by inhibition of nitrergic Rheb degradation by Harraz, M M, Tyagi, R, Cortés, P, Snyder, S H

“…As traditional antidepressants act only after weeks/months, the discovery that ketamine, an antagonist of glutamate/ N -methyl- d -aspartate (NMDA) receptors,…”
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The distribution of nitric oxide synthase-containing autonomic preganglionic terminals in the rat by Anderson, C R, Edwards, S L, Furness, J B, Bredt, D S, Snyder, S H

“…Nitric oxide synthase (NOS)-immunoreactivity was co-localised with NADPH diaphorase activity in preganglionic sympathetic neurons and in their terminals in…”
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Inositol hexakisphosphate kinase-1 regulates behavioral responses via GSK3 signaling pathways by Chakraborty, A, Latapy, C, Xu, J, Snyder, S H, Beaulieu, J-M

“…Glycogen synthase kinase 3 (GSK3), a prominent enzyme in carbohydrate metabolism, also has a major role in brain function. It is physiologically regulated by…”
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Neuronal inositol 1,4,5-trisphosphate receptor localized to the plasma membrane of olfactory cilia by Cunningham, A M, Ryugo, D K, Sharp, A H, Reed, R R, Snyder, S H, Ronnett, G V

“…Both the cyclic adenosine 3',5'-monophosphate and the phosphoinositide second messenger systems are involved in olfactory signal transduction. The inositol…”
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