Search Results - "Snyder, Marylynn"
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Signal Transducers and Activators of Transcription 3 (STAT3) Directly Regulates Cytokine-induced Fascin Expression and Is Required for Breast Cancer Cell Migration
Published in The Journal of biological chemistry (11-11-2011)“…The cytokines oncostatin M (OSM) and IL-6 promote breast cancer cell migration and metastasis. Both cytokines activate STAT3, a member of the STAT (signal…”
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Identification of Novel Direct Stat3 Target Genes for Control of Growth and Differentiation
Published in The Journal of biological chemistry (15-02-2008)“…Signal transducer and activator of transcription 3 (Stat3) is a key regulator of gene expression in response to signaling of the glycoprotein 130 (gp130)…”
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Stat3 Directly Controls the Expression of Tbx5, Nkx2.5, and GATA4 and Is Essential for Cardiomyocyte Differentiation of P19CL6 Cells
Published in The Journal of biological chemistry (30-07-2010)“…The transcription factor Stat3 (signal transducer and activator of transcription 3) mediates many physiological processes, including embryogenesis, stem cell…”
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Stat3 is essential for neuronal differentiation through direct transcriptional regulation of the Sox6 gene
Published in FEBS letters (03-01-2011)“…The transcription factor Signal Transducer and Activator of Transcription 3 (Stat3) functions in various cellular processes including neuronal differentiation…”
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The Minichromosome Maintenance Proteins 2-7 (MCM2-7) Are Necessary for RNA Polymerase II (Pol II)-mediated Transcription
Published in The Journal of biological chemistry (15-05-2009)“…The MCM2-7 (minichromosome maintenance) proteins are a family of evolutionarily highly conserved proteins. They are essential for DNA replication in yeast and…”
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The DNA Replication Factor MCM5 Is Essential for Stat1-Mediated Transcriptional Activation
Published in Proceedings of the National Academy of Sciences - PNAS (11-10-2005)“…The eukaryotic minichromosome maintenance (MCM) family of proteins (MCM2-MCM7) is evolutionarily conserved from yeast to human. These proteins are essential…”
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Linear Derivatives of Saccharomyces cerevisiae Chromosome III Can Be Maintained in the Absence of Autonomously Replicating Sequence Elements
Published in Molecular and Cellular Biology (01-07-2007)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Regulation of Stat3 transcriptional activity by the conserved LPMSP motif for OSM and IL-6 signaling
Published in FEBS letters (30-10-2006)“…To achieve maximal transcriptional activity in response to gp130 cytokines, Serine-727 (Ser-727) of Stat3 is phosphorylated. Ser-727 resides in the LPMSP…”
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A Signal Transducer and Activator of Transcription 3·Nuclear Factor κB (Stat3·NFκB) Complex Is Necessary for the Expression of Fascin in Metastatic Breast Cancer Cells in Response to Interleukin (IL)-6 and Tumor Necrosis Factor (TNF)-α
Published in The Journal of biological chemistry (24-10-2014)“…IL-6 mediated activation of Stat3 is a major signaling pathway in the process of breast cancer metastasis. One important mechanism by which the IL-6/Stat3…”
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Critical Roles of STAT3 in β-Adrenergic Functions in the Heart
Published in Circulation (New York, N.Y.) (05-01-2016)“…BACKGROUND—β-Adrenergic receptors (βARs) play paradoxical roles in the heart. On one hand, βARs augment cardiac performance to fulfill the physiological…”
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The Conserved Leu-724 Residue Is Required for Both Serine Phosphorylation and Co-activator Recruitment for Stat1-mediated Transcription Activation in Response to Interferon-Î
Published in The Journal of biological chemistry (23-12-2005)“…The signal transducer and activator of transcription (STAT) proteins, a family of latent cytoplasmic transcription factors, become activated in response to…”
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The Conserved Leu-724 Residue Is Required for Both Serine Phosphorylation and Co-activator Recruitment for Stat1-mediated Transcription Activation in Response to Interferon-γ
Published in The Journal of biological chemistry (23-12-2005)“…The signal transducer and activator of transcription (STAT) proteins, a family of latent cytoplasmic transcription factors, become activated in response to…”
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