Search Results - "Snyder, Heidi Link"

Promiscuous liberation of MHC‐class I‐binding peptides from the C termini of membrane and soluble proteins in the secretory pathway by Link Snyder, Heidi, Bačík, Igor, Yewdell, Jonathan W., Behrens, Timothy W., Bennink, Jack R.

“…TAP can efficiently transport peptides up to twice as long as those bound to MHC class I molecules, suggesting a role for endoplasmic reticulum (ER) proteases…”
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Trimming of antigenic peptides in an early secretory compartment by Snyder, H L, Yewdell, J W, Bennink, J R

“…Major histocompatibility complex (MHC) class I molecules bind peptides of 8-10 residues in the endoplasmic reticulum (ER) and convey them to the cell surface…”
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The generation of MHC class I-associated peptides is only partially inhibited by proteasome inhibitors: involvement of nonproteasomal cytosolic proteases in antigen processing? by Vinitsky, A, Anton, LC, Snyder, HL, Orlowski, M, Bennink, JR, Yewdell, JW

“…The proteasome is believed to participate in the generation of a large percentage of peptide ligands for MHC class I molecules. This conclusion is based…”
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Two novel routes of transporter associated with antigen processing (TAP)-independent major histocompatibility complex class I antigen processing by Snyder, H L, Bacík, I, Bennink, J R, Kearns, G, Behrens, T W, Bächi, T, Orlowski, M, Yewdell, J W

“…Jaw1 is an endoplasmic reticulum (ER) resident protein representative of a class of proteins post translationally inserted into membranes via a type II…”
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Generating MHC class I ligands from viral gene products by Yewdell, Jonathan, Anton, Luis C., Bacik, Igor, Schubert, Ulrich, Snyder, Heidi Link, Bennink, Jack R.

“…MHC class I molecules function to present peptides comprised of eight to I 1 residues to CD8+ T lymphocytes. Here we review the efforts of our laboratory lo…”
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MHC class I-dependent presentation of exoerythrocytic antigens to CD8+ T lymphocytes is required for protective immunity against Plasmodium berghei by White, KL, Snyder, HL, Krzych, U

“…T lymphocytes are believed to play a major role in protection against malaria. Previous experiments using in vivo depletion of CD8+ T cells, reconstitution…”
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Introduction of a Glycosylation Site into a Secreted Protein Provides Evidence for an Alternative Antigen Processing Pathway: Transport of Precursors of Major Histocompatability Complex Class I–Restricted Peptides from the Endoplasmic Reticulum to the Cytosol by Bačík, Igor, Snyder, Heidi Link, Antón, Luis C., Russ, Gustav, Chen, Weisan, Bennink, Jack R., Urge, Laszlo, Otvos, Laszlo, Dudkowska, Boguslawa, Eisenlohr, Laurence, Yewdell, Jonathan W.

“…We found that the presentation of a H-2Kd-restricted determinant from influenza virus nucleoprotein (NP) to T cells is strictly dependent on expression of the…”
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