Search Results - "Snyder, Deann T."

A TLR4 agonist liposome formulation effectively stimulates innate immunity and enhances protection from bacterial infection by Hedges, Jodi F., Snyder, Deann T., Robison, Amanda, Thompson, Macy A., Aspelin, Klara, Plewa, Jack, Baldridge, Jory, Jutila, Mark A.

“…Stimulation of innate immunity can protect against infectious insult and could be used in combination with other therapies. Since antibiotic resistance is an…”
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Intrinsic signal amplification by type III CRISPR-Cas systems provides a sequence-specific SARS-CoV-2 diagnostic by Santiago-Frangos, Andrew, Hall, Laina N., Nemudraia, Anna, Nemudryi, Artem, Krishna, Pushya, Wiegand, Tanner, Wilkinson, Royce A., Snyder, Deann T., Hedges, Jodi F., Cicha, Calvin, Lee, Helen H., Graham, Ava, Jutila, Mark A., Taylor, Matthew P., Wiedenheft, Blake

“…There is an urgent need for inexpensive new technologies that enable fast, reliable, and scalable detection of viruses. Here, we repurpose the type III…”
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An ADAM17-Neutralizing Antibody Reduces Inflammation and Mortality While Increasing Viral Burden in a COVID-19 Mouse Model by Hedges, Jodi F., Snyder, Deann T., Robison, Amanda, Grifka-Walk, Heather M., Blackwell, Karlin, Shepardson, Kelly, Kominsky, Douglas, Rynda-Apple, Agnieszka, Walcheck, Bruce, Jutila, Mark A.

“…Angiotensin Converting Enzyme 2 (ACE2) is the primary cell entry receptor for SARS-CoV and SARS-CoV-2 viruses. A disintegrin and metalloproteinase 17 (ADAM17)…”
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Effect of Inactivation Methods on SARS-CoV-2 Virion Protein and Structure by Loveday, Emma K, Hain, Kyle S, Kochetkova, Irina, Hedges, Jodi F, Robison, Amanda, Snyder, Deann T, Brumfield, Susan K, Young, Mark J, Jutila, Mark A, Chang, Connie B, Taylor, Matthew P

“…The risk posed by Severe Acute Respiratory Syndrome Coronavirus -2 (SARS-CoV-2) dictates that live-virus research is conducted in a biosafety level 3 (BSL3)…”
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Getting “Inside” Type I IFNs: Type I IFNs in Intracellular Bacterial Infections by Snyder, Deann T., Jutila, Mark A., Hedges, Jodi F.

“…Type I interferons represent a unique and complex group of cytokines, serving many purposes during innate and adaptive immunity. Discovered in the context of…”
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Titers, Prevalence, and Duration of SARS-CoV-2 Antibodies in a Local COVID-19 Outbreak and Following Vaccination by Hedges, Jodi F., Thompson, Macy A., Snyder, Deann T., Robison, Amanda, Taylor, Matthew P., Jutila, Mark A.

“…Information concerning the development of neutralizing antibodies and their duration will be critical to establishing herd immunity for COVID-19. We sought to…”
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Severe Acute Respiratory Syndrome Coronavirus 2 Is Detected in the Gastrointestinal Tract of Asymptomatic Endoscopy Patients but Is Unlikely to Pose a Significant Risk to Healthcare Personnel by Cherne, Michelle D., Gentry, Andrew B., Nemudraia, Anna, Nemudryi, Artem, Hedges, Jodi F., Walk, Heather, Blackwell, Karlin, Snyder, Deann T., Jerome, Maria, Madden, Wyatt, Hashimi, Marziah, Sebrell, T. Andrew, King, David B., Plowright, Raina K., Jutila, Mark A., Wiedenheft, Blake, Bimczok, Diane

“…Recent evidence suggests that the gut is an additional target for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. However, whether…”
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SARS-CoV-2 genomic surveillance identifies naturally occurring truncation of ORF7a that limits immune suppression by Nemudryi, Artem, Nemudraia, Anna, Wiegand, Tanner, Nichols, Joseph, Snyder, Deann T., Hedges, Jodi F., Cicha, Calvin, Lee, Helen, Vanderwood, Karl K., Bimczok, Diane, Jutila, Mark A., Wiedenheft, Blake

“…Over 950,000 whole-genome sequences of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have been determined for viruses isolated from around the…”
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Solute carrier 11A1 is expressed by innate lymphocytes and augments their activation by Hedges, Jodi F, Kimmel, Emily, Snyder, Deann T, Jerome, Maria, Jutila, Mark A

“…Solute carrier 11A1 (SLC11A1) is a divalent ion transporter formerly known as the natural resistance-associated macrophage protein (NRAMP1) and the Bcg/Lsh/Ity…”
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Expression of human TLR4/myeloid differentiation factor 2 directs an early innate immune response associated with modest increases in bacterial burden during Coxiella burnetii infection by Robison, Amanda, Snyder, Deann T, Christensen, Kelly, Kimmel, Emily, Hajjar, Adeline M, Jutila, Mark A, Hedges, Jodi F

“…Human TLR4 (hTLR4) and mouse TLR4 molecules respond differently to hypo-acylated LPS. The LPS of Coxiella burnetii is hypo-acylated and heavily glycosylated…”
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Oral delivery of oligomeric procyanidins in Apple Poly® enhances type I IFN responses in vivo by Snyder, Deann T., Robison, Amanda, Kemoli, Sharon, Kimmel, Emily, Holderness, Jeff, Jutila, Mark A., Hedges, Jodi F.

“…Augmentation of responses to type I IFN following ingestion of Apple Poly® may have broad therapeutic application to enhance antiviral immunity, or suppress…”
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Amphotericin B stimulates γδ T and NK cells, and enhances protection from Salmonella infection by Hedges, Jodi F, Mitchell, Angela M, Jones, Kerri, Kimmel, Emily, Ramstead, Andrew G, Snyder, Deann T, Jutila, Mark A

“…Amphotericin B (AmB) is a commonly used antifungal drug, with well-documented effects on cellular immune responses. We determined that AmB-stimulated γδ T-cell…”
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Titers, prevalence and duration of SARS-CoV-2 antibodies in two waves of a local COVID-19 outbreak by Hedges, Jodi F, Thomspon, Macy A., Snyder, Deann T., Robison, Amanda, Taylor, Matthew P., Jutila, Mark A

“…Information concerning the development of neutralizing antibodies and their duration will be critical to establishing herd immunity for COVID-19. We sought to…”
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ADAM-17 protease promotes inflammation and mortality while decreasing viral burden in a COVID-19 mouse model by Hedges, Jodi F, Snyder, Deann T., Robison, Amanda, Walk, Heather, Havlak, Karlin, Shepardson, Kelly, Kominsky, Douglas, Rynda-Apple, Agnieszka, Walcheck, Bruce, Jutila, Mark A.

“…Angiotensin Converting Enzyme 2 (ACE2) is the primary cell entry receptor for SARS-CoV-1 and SARS-CoV-2 viruses. A disintegrin and metalloproteinase 17…”
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Expression of human TLR4/myeloid differentiation factor 2 directs an early innate immune response associated with modest increases in bacterial burden during infection by Amanda Robison, Deann T Snyder, Kelly Christensen, Emily Kimmel, Adeline M Hajjar, Mark A Jutila, Jodi F Hedges

“…Human TLR4 (hTLR4) and mouse TLR4 molecules respond differently to hypo-acylated LPS. The LPS of Coxiella burnetii is hypo-acylated and heavily glycosylated…”
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SLC11A1 is expressed by innate lymphocytes and augments their activation1 by Hedges, Jodi F., Kimmel, Emily, Snyder, Deann T., Jerome, Maria, Jutila, Mark A.

“…SLC11A1 is a divalent ion transporter formerly known as the natural resistance-associated macrophage protein (NRAMP1) and the Bcg/Lsh/Ity locus. SLC11A1 was…”
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