Search Results - "Snyder, Amanda M."

Iron, the substantia nigra and related neurological disorders by Snyder, Amanda M., Connor, James R.

“…Iron status is higher in the substantia nigra than in other brain regions but can fluctuate as function of diet and genetics and disease. Of particular note is…”
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Low plasma serotonin linked to higher nigral iron in Parkinson’s disease by Jellen, Leslie C., Lewis, Mechelle M., Du, Guangwei, Wang, Xi, Galvis, Martha L. Escobar, Krzyzanowski, Stanislaw, Capan, Colt D., Snyder, Amanda M., Connor, James. R., Kong, Lan, Mailman, Richard B., Brundin, Patrik, Brundin, Lena, Huang, Xuemei

“…A growing body of evidence suggests nigral iron accumulation plays an important role in the pathophysiology of Parkinson’s disease (PD), contributing to…”
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Brain Metal Distribution and Neuro-Inflammatory Profiles after Chronic Vanadium Administration and Withdrawal in Mice by Folarin, Oluwabusayo R, Snyder, Amanda M, Peters, Douglas G, Olopade, Funmilayo, Connor, James R, Olopade, James O

“…Vanadium is a potentially toxic environmental pollutant and induces oxidative damage in biological systems including the central nervous system (CNS). Its…”
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A Possible Role for Platelet-Activating Factor Receptor in Amyotrophic Lateral Sclerosis Treatment by Briones, Marcelo R S, Snyder, Amanda M, Ferreira, Renata C, Neely, Elizabeth B, Connor, James R, Broach, James R

“…Amyotrophic lateral sclerosis (ALS) is the third most prevalent neurodegenerative disease affecting upper and lower motor neurons. An important pathway that…”
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Mitochondrial Ferritin in the Substantia Nigra in Restless Legs Syndrome by Snyder, Amanda M, Wang, XinSheng, Patton, Stephanie M, Arosio, Paolo, Levi, Sonia, Earley, Christopher J, Allen, Richard P, Connor, James R

“…Restless legs syndrome (RLS) is a neurological disorder that is thought to involve decreased iron availability in the brain. Iron is required for oxidative…”
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Regional and cellular distribution of mitochondrial ferritin in the mouse brain by Snyder, Amanda M., Neely, Elizabeth B., Levi, Sonia, Arosio, Paolo, Connor, James R.

“…Iron and mitochondrial dysfunction are important in many neurodegenerative diseases. Several iron transport proteins have been identified that are associated…”
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Prevalence of Late‐Stage Parkinson's Disease in the US Healthcare System: Insights from TriNetX by De Jesus, Sol, Daya, Annika, Blumberger, Liba, Lewis, Mechelle M., Leslie, Doug, Tabbal, Samer D., Dokholyan, Rachel, Snyder, Amanda M., Mailman, Richard B., Huang, Xuemei

“…Background Patients in late‐stage Parkinson's disease (PDLS) are caregiver‐dependent, have low quality of life, and higher healthcare costs. Objective To…”
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Susceptibility MRI captures nigral pathology in patients with parkinsonian syndromes by Lewis, Mechelle M., Du, Guangwei, Baccon, Jennifer, Snyder, Amanda M., Murie, Ben, Cooper, Felicia, Stetter, Christy, Kong, Lan, Sica, Christopher, Mailman, Richard B., Connor, James R., Huang, Xuemei

“…ABSTRACT Background: Parkinsonisms are neurodegenerative disorders characterized pathologically by α‐synuclein‐positive (e.g., PD, diffuse Lewy body disease,…”
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The Nrf2-mediated defense mechanism associated with HFE genotype limits vulnerability to oxidative stress-induced toxicity by Song, Insung Y., Snyder, Amanda M., Kim, Yunsung, Neely, Elizabeth B., Wade, Quinn W., Connor, James R.

“…There is considerable interest in gene and environment interactions in neurodegenerative diseases. The HFE (homeostatic iron regulator) gene variant (H63D) is…”
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Predictive link between systemic metabolism and cytokine signatures in the brain of apolipoprotein E ε4 mice by Fleeman, Rebecca M., Snyder, Amanda M., Kuhn, Madison K., Chan, Dennis C., Smith, Grace C., Crowley, Nicole A., Arnold, Amy C., Proctor, Elizabeth A.

“…•APOE4 and APOE3 male mice do not differ in weight and adiposity gain with age.•APOE4 female mice experience attenuated increases in weight and adiposity with…”
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Implications of Environmental Stress during Seed Development on Reproductive and Seed Bank Persistence Traits in Wild Oat (Avena fatua L.) by Gallagher, Robert, Granger, Kristen, Snyder, Amanda, Pittmann, Dennis, Fuerst, E.

“…Weeds produce seed under a wide range of conditions, depending on timing of emergence, prevailing crop, soil microsites, and climatic conditions, among other…”
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HFE Genotype Restricts the Response to Paraquat in a Mouse Model of Neurotoxicity by Nixon, Anne M., Meadowcroft, Mark D., Neely, Elizabeth B., Snyder, Amanda M., Purnell, Carson J., Wright, Justin, Lamendella, Regina, Nandar, Wint, Huang, Xuemei, Connor, James R.

“…Parkinson's disease is marked clinically by motor dysfunction and pathologically by dopaminergic cell loss in the substantia nigra and iron accumulation in the…”
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Amyloid-β Pathology-Specific Cytokine Secretion Suppresses Neuronal Mitochondrial Metabolism by Kuhn, Madison K., Fleeman, Rebecca M., Beidler, Lynne M., Snyder, Amanda M., Chan, Dennis C., Proctor, Elizabeth A.

“…Introduction Neuroinflammation and metabolic dysfunction are early alterations in Alzheimer’s disease (AD) brain that are thought to contribute to disease…”
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Increased R2 in the Caudate Nucleus of Asymptomatic Welders by Lee, Eun-Young, Flynn, Michael R, Du, Guangwei, Li, Yunqing, Lewis, Mechelle M, Herring, Amy H, Van Buren, Eric, Van Buren, Scott, Kong, Lan, Fry, Rebecca C, Snyder, Amanda M, Connor, James R, Yang, Qing X, Mailman, Richard B, Huang, Xuemei

“…Welding has been associated with neurobehavioral disorders. Welding fumes contain several metals including copper (Cu), manganese (Mn), and iron (Fe) that may…”
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The Development of a Digital Literacy Instrument to Measure the Frequency of Digital Skills Usage in the Workplace by Snyder, Amanda M

“…The ever-changing advances in technology require digital literacy skills for success in the workplace. To determine the critical digital literacy skills needed…”
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Cellular iron status influences cell motility in glioblastoma by Shenoy, Ganesh, Kuhn, Madison, Palsa, Kondaiah, Slagle-Webb, Becky, Snyder, Amanda M., Khunsriraksakul, Chachrit, Troike, Katie, Lathia, Justin D., Wang, Hong-Gang, Proctor, Elizabeth A., Connor, James R.

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Increased R2 in the caudate nucleus of asymptomatic welders by Lee, Eun-Young, Flynn, Michael R., Du, Guangwei, Li, Yunqing, Lewis, Mechelle M., Herring, Amy H., Van Buren, Eric, Van Buren, Scott, Kong, Lan, Fry, Rebecca C., Snyder, Amanda M., Connor, James R., Yang, Qing X., Mailman, Richard B., Huang, Xuemei

“…Welding has been associated with neurobehavioral disorders. Welding fumes contain several metals including copper (Cu), manganese (Mn), and iron (Fe) that may…”
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Alternative Strategies for Transitioning to Organic Production in Direct-Seeded Grain Systems in Eastern Washington. I. Crop Agronomy by Gallagher, Robert S, Pittmann, Dennis, Snyder, Amanda M, Koenig, Richard T, Fuerst, E. Patrick, Burke, Ian C, Hoagland, Lori

“…Organic grain production is not common to eastern Washington, but offers attractive market opportunities if systems can be developed that are compatible with…”
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