Search Results - "Snowman, A M"

Macrophage Nitric Oxide Synthase Gene: Two Upstream Regions Mediate Induction by Interferon γ and Lipopolysaccharide by Lowenstein, Charles J., Alley, Evan W., Raval, Prafulla, Snowman, Adele M., Snyder, Solomon H., Russell, Stephen W., Murphy, William J.

“…The promoter region of the mouse gene for macrophage-inducible nitric oxide synthase (mac-NOS; EC 1.14.13.39) has been characterized. A putative TATA box is 30…”
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Isolation of the Mitochondrial Benzodiazepine Receptor: Association with the Voltage-Dependent Anion Channel and the Adenine Nucleotide Carrier by McEnery, Maureen W., Snowman, Adele M., Trifiletti, Rosario R., Snyder, Solomon H.

“…The mitochondrial benzodiazepine receptor (mBzR) has been solubilized with retention of reversible ligand binding, and the associated subunits were…”
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Calcium Sensing Receptor: Molecular Cloning in Rat and Localization to Nerve Terminals by Ruat, Martial, Molliver, Mark E., Snowman, Adele M., Snyder, Solomon H.

“…We have molecularly cloned a calcium sensing receptor (CaSR) from a rat striatal cDNA library. Rat CaSR displays 92% overall homology to its bovine counterpart…”
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Selective labeling of serotonin uptake sites in rat brain by [3H]citalopram contrasted to labeling of multiple sites by [3H]imipramine by D'Amato, R J, Largent, B L, Snowman, A M, Snyder, S H

“…Citalopram is a potent and selective inhibitor of neuronal serotonin uptake. In rat brain membranes [3H]citalopram demonstrates saturable and reversible…”
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High brain densities of the immunophilin FKBP colocalized with calcineurin by Steiner, Joseph P, Dawson, Ted M, Fotuhi, Majid, Glatt, Charles E, Snowman, Adele M, Cohen, Noam, Snyder, Solomon H

“…The immunophilins cyclophilin and FK506 binding protein (FKBP) are small, predominantly soluble proteins that bind the immunosuppressant drugs cyclosporin A…”
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Purified ω-Conotoxin GVIA Receptor of Rat Brain Resembles a Dihydropyridine-Sensitive L-Type Calcium Channel by MCENERY, M. W, SNOWMAN, A. M, SHARP, A. H, ADAMS, M. E, SNYDER, S. H

“…The ω-conotoxin GVIA (CTX) receptor has been purified 1900-fold to apparent homogeneity by monitoring both reversible binding of125I-labeled CTX (125I-CTX) and…”
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Omega-conotoxin GVIA binding to a high-affinity receptor in brain: characterization, calcium sensitivity, and solubilization by Wagner, JA, Snowman, AM, Biswas, A, Olivera, BM, Snyder, SH

“…We describe unique, high-affinity binding sites for omega[125I]conotoxin GVIA in membranes from rat brain and rabbit sympathetic ganglia which appear to be…”
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Synthesis of diphosphoinositol pentakisphosphate by a newly identified family of higher inositol polyphosphate kinases by Saiardi, Adolfo, Erdjument-Bromage, Hediye, Snowman, Adele M., Tempst, Paul, Snyder, Solomon H.

“…Inositol (1,4,5) trisphosphate (Ins(1,4,5)P 3) is a well-known messenger molecule that releases calcium from intracellular stores. Homologues with up to six…”
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(-)-[3H] desmethoxyverapamil labels multiple calcium channel modulator receptors in brain and skeletal muscle membranes: differentiation by temperature and dihydropyridines by Reynolds, I J, Snowman, A M, Snyder, S H

“…The verapamil-like calcium channel modulator, (-)-[3H]desmethoxyverapamil binds to multiple sites in microsomal membrane preparations from brain and skeletal…”
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Novel antipsychotic drugs share high affinity for sigma receptors by Largent, B L, Wikström, H, Snowman, A M, Snyder, S H

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CAPON: A Protein Associated with Neuronal Nitric Oxide Synthase that Regulates Its Interactions with PSD95 by Jaffrey, Samie R, Snowman, Adele M, Eliasson, Mikael J.L, Cohen, Noam A, Snyder, Solomon H

“…Nitric oxide (NO) produced by neuronal nitric oxide synthase (nNOS) is important for N-methyl-D-aspartate (NMDA) receptor-dependent neurotransmitter release,…”
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Alterations in Calcium Antagonist Receptors and Sodium-Calcium Exchange in Cardiomyopathic Hamster Tissues by Wagner, John A, Weisman, Harlan F, Snowman, Adele M, Reynolds, Ian J, Weisfeldt, Myron L, Snyder, Solomon H

“…The Syrian cardiomyopathic (CM) hamster (BIO 14.6) develops a progressive cardiomyopathy characterized by cellular necrosis, hypertrophy, and, eventually,…”
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Odorant-binding protein. Characterization of ligand binding by PEVSNER, J, HOU, V, SNOWMAN, A. M, SNYDER, S. H

“…We have characterized the odorant binding properties of purified bovine odorant-binding protein (OBP) using as a ligand [3H]3,7-dimethyloctan-1-ol ([3H]DMO). A…”
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Identification and Characterization of a Novel Inositol Hexakisphosphate Kinase by Saiardi, Adolfo, Nagata, Eiichiro, Luo, Hongbo R., Snowman, Adele M., Snyder, Solomon H.

“…The inositol pyrophosphate disphosphoinositol pentakisphosphate (PP-InsP3/InsP7) is formed in mammals by two recently cloned inositol hexakiphosphate kinases,…”
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Neuronal Nitric-Oxide Synthase Localization Mediated by a Ternary Complex with Synapsin and CAPON by Jaffrey, Samie R., Benfenati, Fabio, Snowman, Adele M., Czernik, Andrew J., Snyder, Solomon H.

“…The specificity of the reactions of nitric oxide (NO) with its neuronal targets is determined in part by the precise localizations of neuronal NO synthase…”
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Chloride-dependent enhancement by barbiturates of gamma-aminobutyric acid receptor binding by Olsen, R W, Snowman, A M

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Cetirizine: actions on neurotransmitter receptors by Snowman, A M, Snyder, S H

“…First-generation H1-antagonist antihistamines, such as hydroxyzine, have the ability to cross the blood-brain barrier and cause sedation, which limits their…”
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Phenylalkylamine-sensitive calcium channels in osteoblast-like osteosarcoma cells. Characterization by ligand binding and single channel recordings by Guggino, S E, Wagner, J A, Snowman, A M, Hester, L D, Sacktor, B, Snyder, S H

“…(-)-[3H]Desmethoxyverapamil ((-)-DMV) binds saturably to homogenates of the osteoblast-like cell lines UMR 106 and ROS 17/2.8 with KD values of 45 and 61 nM…”
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Mammalian Inositol Polyphosphate Multikinase Synthesizes Inositol 1,4,5-Trisphosphate and an Inositol Pyrophosphate by Saiardi, Adolfo, Nagata, Eiichiro, Luo, Hongbo R., Sawa, Akira, Luo, Xiaojiang, Snowman, Adele M., Snyder, Solomon H.

“…Using a consensus sequence in inositol phosphate kinase, we have identified and cloned a 44-kDa mammalian inositol phosphate kinase with broader catalytic…”
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[3H]opipramol labels a novel binding site and sigma receptors in rat brain membranes by Ferris, C D, Hirsch, D J, Brooks, B P, Snowman, A M, Snyder, S H

“…Opipramol (OP), a clinically effective antidepressant with a tricyclic structure, is inactive as an inhibitor of biogenic amine uptake. [3H]Opipramol binds…”
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