Search Results - "Snowden, A"

Hematopoietic Stem Cell Transplantation for Autoimmune Disease by Alexander, Tobias, Greco, Raffaella, Snowden, John A

“…The introduction of targeted biologic therapies has changed the treatment landscape for autoimmune diseases (ADs) substantially, but although these therapies…”
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Methotrexate Is a JAK/STAT Pathway Inhibitor by Thomas, Sally, Fisher, Katherine H, Snowden, John A, Danson, Sarah J, Brown, Stephen, Zeidler, Martin P

“…The JAK/STAT pathway transduces signals from multiple cytokines and controls haematopoiesis, immunity and inflammation. In addition, pathological activation is…”
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Impact of a five-dimensional framework on R&D productivity at AstraZeneca by Morgan, Paul, Brown, Dean G., Lennard, Simon, Anderton, Mark J., Barrett, J. Carl, Eriksson, Ulf, Fidock, Mark, Hamrén, Bengt, Johnson, Anthony, March, Ruth E., Matcham, James, Mettetal, Jerome, Nicholls, David J., Platz, Stefan, Rees, Steve, Snowden, Michael A., Pangalos, Menelas N.

“…In 2011, AstraZeneca set out to improve its research and development (R&D) productivity by focusing decision-making using a framework with five technical…”
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Hematopoietic cell transplantation and cellular therapy survey of the EBMT: monitoring of activities and trends over 30 years by Passweg, Jakob R., Baldomero, Helen, Chabannon, Christian, Basak, Grzegorz W., de la Cámara, Rafael, Corbacioglu, Selim, Dolstra, Harry, Duarte, Rafael, Glass, Bertram, Greco, Raffaella, Lankester, Arjan C., Mohty, Mohamad, Peffault de Latour, Régis, Snowden, John A., Yakoub-Agha, Ibrahim, Kröger, Nicolaus

“…Numbers of Hematopoietic cell transplantation (HCT) in Europe and collaborating countries continues to rise with 48,512 HCT in 43,581 patients, comprising of…”
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Use of haploidentical stem cell transplantation continues to increase: the 2015 European Society for Blood and Marrow Transplant activity survey report by Passweg, J R, Baldomero, H, Bader, P, Bonini, C, Duarte, R F, Dufour, C, Gennery, A, Kröger, N, Kuball, J, Lanza, F, Montoto, S, Nagler, A, Snowden, J A, Styczynski, J, Mohty, M

“…Hematopoietic stem cell transplantation (HSCT) is an established procedure for many acquired and congenital disorders of the hematopoietic system. A record…”
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Autologous haematopoietic stem cell transplantation and other cellular therapy in multiple sclerosis and immune-mediated neurological diseases: updated guidelines and recommendations from the EBMT Autoimmune Diseases Working Party (ADWP) and the Joint Accreditation Committee of EBMT and ISCT (JACIE) by Sharrack, Basil, Saccardi, Riccardo, Alexander, Tobias, Badoglio, Manuela, Burman, Joachim, Farge, Dominique, Greco, Raffaella, Jessop, Helen, Kazmi, Majid, Kirgizov, Kirill, Labopin, Myriam, Mancardi, Gianluigi, Martin, Roland, Moore, John, Muraro, Paolo A., Rovira, Montserrat, Sormani, Maria Pia, Snowden, John A.

“…These updated EBMT guidelines review the clinical evidence, registry activity and mechanisms of action of haematopoietic stem cell transplantation (HSCT) in…”
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Indications for haematopoietic cell transplantation for haematological diseases, solid tumours and immune disorders: current practice in Europe, 2022 by Snowden, John A., Sánchez-Ortega, Isabel, Corbacioglu, Selim, Basak, Grzegorz W., Chabannon, Christian, de la Camara, Rafael, Dolstra, Harry, Duarte, Rafael F., Glass, Bertram, Greco, Raffaella, Lankester, Arjan C., Mohty, Mohamad, Neven, Bénédicte, de Latour, Régis Peffault, Pedrazzoli, Paolo, Peric, Zinaida, Yakoub-Agha, Ibrahim, Sureda, Anna, Kröger, Nicolaus

“…For over two decades, the EBMT has updated recommendations on indications for haematopoietic cell transplantation (HCT) practice based on clinical and…”
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Death after hematopoietic stem cell transplantation: changes over calendar year time, infections and associated factors by Styczyński, Jan, Tridello, Gloria, Koster, Linda, Iacobelli, Simona, van Biezen, Anja, van der Werf, Steffie, Mikulska, Małgorzata, Gil, Lidia, Cordonnier, Catherine, Ljungman, Per, Averbuch, Diana, Cesaro, Simone, de la Camara, Rafael, Baldomero, Helen, Bader, Peter, Basak, Grzegorz, Bonini, Chiara, Duarte, Rafael, Dufour, Carlo, Kuball, Jurgen, Lankester, Arjan, Montoto, Silvia, Nagler, Arnon, Snowden, John A., Kröger, Nicolaus, Mohty, Mohamad, Gratwohl, Alois

“…Information on incidence, and factors associated with mortality is a prerequisite to improve outcome after hematopoietic stem cell transplantation (HSCT)…”
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Management of adults and children undergoing chimeric antigen receptor T-cell therapy: best practice recommendations of the European Society for Blood and Marrow Transplantation (EBMT) and the Joint Accreditation Committee of ISCT and EBMT (JACIE) by Yakoub-Agha, Ibrahim, Chabannon, Christian, Bader, Peter, Basak, Grzegorz W, Bonig, Halvard, Ciceri, Fabio, Corbacioglu, Selim, Duarte, Rafael F, Einsele, Hermann, Hudecek, Michael, Kersten, Marie José, Köhl, Ulrike, Kuball, Jürgen, Mielke, Stephan, Mohty, Mohamad, Murray, John, Nagler, Arnon, Robinson, Stephen, Saccardi, Riccardo, Sanchez-Guijo, Fermin, Snowden, John A, Srour, Micha, Styczynski, Jan, Urbano-Ispizua, Alvaro, Hayden, Patrick J, Kröger, Nicolaus

“…Chimeric antigen receptor (CAR) T cells are a novel class of anti-cancer therapy in which autologous or allogeneic T cells are engineered to express a CAR…”
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Investigating the mechanism for AMP activation of the AMP-activated protein kinase cascade by Sanders, Matthew J, Grondin, Pascal O, Hegarty, Bronwyn D, Snowden, Michael A, Carling, David

“…AMPK (AMP-activated protein kinase) is activated allosterically by AMP and by phosphorylation of Thr172 within the catalytic alpha subunit. Here we show that…”
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TOPOLOGICAL NOETHERIANITY FOR ALGEBRAIC REPRESENTATIONS OF INFINITE RANK CLASSICAL GROUPS by EGGERMONT, R. H., SNOWDEN, A.

“…Draisma recently proved that polynomial representations of GL ∞ are topologically noetherian. We generalize this result to algebraic representations of…”
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Hematopoietic stem cell therapy for autoimmune diseases – Clinical experience and mechanisms by Alexander, Tobias, Farge, Dominique, Badoglio, Manuela, Lindsay, James O., Muraro, Paolo A., Snowden, John A.

“…With accumulating evidence and improved outcomes along with recognition that modern biological therapies are not universally effective, require chronic…”
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Haematopoietic SCT in severe autoimmune diseases: updated guidelines of the European Group for Blood and Marrow Transplantation by Snowden, J A, Saccardi, R, Allez, M, Ardizzone, S, Arnold, R, Cervera, R, Denton, C, Hawkey, C, Labopin, M, Mancardi, G, Martin, R, Moore, J J, Passweg, J, Peters, C, Rabusin, M, Rovira, M, van Laar, J M, Farge, D

“…In 1997, the first consensus guidelines for haematopoietic SCT (HSCT) in autoimmune diseases (ADs) were published, while an international coordinated clinical…”
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Outcomes of allogeneic haematopoietic stem cell transplantation from HLA-matched and alternative donors: a European Society for Blood and Marrow Transplantation registry retrospective analysis by Shouval, Roni, Fein, Joshua A, Labopin, Myriam, Kröger, Nicolaus, Duarte, Rafael F, Bader, Peter, Chabannon, Christian, Kuball, Jurgen, Basak, Grzegorz Wladyslaw, Dufour, Carlo, Galimard, Jacques-Emmanuel, Polge, Emmanuelle, Lankester, Arjan, Montoto, Silvia, Snowden, John A, Styczynski, Jan, Yakoub-Agha, Ibrahim, Mohty, Mohamad, Nagler, Arnon

“…The introduction of donors other than HLA-matched siblings has been a pivotal change in stem cell transplantation. We aimed to assess the evolution of outcomes…”
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Non-Responsive Coeliac Disease: A Comprehensive Review from the NHS England National Centre for Refractory Coeliac Disease by Penny, Hugo A, Baggus, Elisabeth M R, Rej, Anupam, Snowden, John A, Sanders, David S

“…Coeliac disease is a common small intestinal enteropathy which manifests following ingestion of gluten in genetically susceptible individuals. Since gluten was…”
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Impact of the SARS-CoV-2 pandemic on hematopoietic cell transplantation and cellular therapies in Europe 2020: a report from the EBMT activity survey by Passweg, Jakob R., Baldomero, Helen, Chabannon, Christian, Corbacioglu, Selim, de la Cámara, Rafael, Dolstra, Harry, Glass, Bertram, Greco, Raffaella, Mohty, Mohamad, Neven, Bénédicte, Peffault de Latour, Régis, Perić, Zinaida, Snowden, John A., Yakoub-Agha, Ibrahim, Sureda, Anna, Kröger, Nicolaus

“…In 2020, 45,364 HCT in 41,016 patients, 18,796 (41%) allogeneic and 26,568 (59%) autologous in 690 centers were reported. Changes observed were as follows:…”
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Autologous stem cell transplantation for progressive systemic sclerosis: a prospective non-interventional study from the European Society for Blood and Marrow Transplantation Autoimmune Disease Working Party by Henes, Joerg, Oliveira, Maria Carolina, Labopin, Myriam, Badoglio, Manuela, Scherer, Hans Ulrich, Del Papa, Nicoletta, Daikeler, Thomas, Schmalzing, Marc, Schroers, Roland, Martin, Thierry, Pugnet, Gregory, Simoes, Belinda, Michonneau, David, Marijt, Erik W A, Lioure, Bruno, Olivier Bay, Jacques, Snowden, John A, Rovira, Montserrat, Huynh, Anne, Onida, Francesco, Kanz, Lothar, Marjanovic, Zora, Farge, Dominique

“…Three randomized controlled trials in early severe systemic sclerosis demonstrated that autologous hematopoietic stem cell transplantation was superior to…”
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Hematopoietic cell transplantation and cellular therapies in Europe 2021. The second year of the SARS-CoV-2 pandemic. A Report from the EBMT Activity Survey by Passweg, Jakob R., Baldomero, Helen, Ciceri, Fabio, Corbacioglu, Selim, de la Cámara, Rafael, Dolstra, Harry, Glass, Bertram, Greco, Raffaella, McLornan, Donal P., Neven, Bénédicte, de Latour, Régis Peffault, Perić, Zinaida, Ruggeri, Annalisa, Snowden, John A., Sureda, Anna

“…In 2021, 47,412 HCT (19,806 (42%) allogeneic and 27,606 (58%) autologous) in 43,109 patients were reported by 694 European centers. 3494 patients received…”
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A systematic review on the factors associated with positive experiences in carers of someone with cancer by Young, J., Snowden, A.

“…The aim of this review was to identify the factors associated with positive experiences in non‐professional carers of someone with a cancer diagnosis. A…”
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Insights Into the Role of Vitamin D as a Biomarker in Stem Cell Transplantation by Soto, Jose Ros, Anthias, Chloe, Madrigal, Alejandro, Snowden, John A

“…Vitamin D was discovered 100 years ago and since then multiple studies have consistently proved its effect on bone health and mineral metabolism. Further…”
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