Search Results - "Snounou, Georges"
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Controlled human malaria infection-Maker and breaker of dogma
Published in PLoS medicine (26-04-2021)“…Jean-Marc Chavatte and Georges Snounou discuss research involving controlled malaria infections…”
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The impact of targeted malaria elimination with mass drug administrations on falciparum malaria in Southeast Asia: A cluster randomised trial
Published in PLoS medicine (15-02-2019)“…The emergence and spread of multidrug-resistant Plasmodium falciparum in the Greater Mekong Subregion (GMS) threatens global malaria elimination efforts. Mass…”
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Plasmodium vivax: restricted tropism and rapid remodeling of CD71-positive reticulocytes
Published in Blood (19-02-2015)“…Plasmodium vivax merozoites only invade reticulocytes, a minor though heterogeneous population of red blood cell precursors that can be graded by levels of…”
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Plasmodium P36 determines host cell receptor usage during sporozoite invasion
Published in eLife (16-05-2017)“…sporozoites, the mosquito-transmitted forms of the malaria parasite, first infect the liver for an initial round of replication before the emergence of…”
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The epidemiology of subclinical malaria infections in South-East Asia: findings from cross-sectional surveys in Thailand-Myanmar border areas, Cambodia, and Vietnam
Published in Malaria journal (30-09-2015)“…The importance of the submicroscopic reservoir of Plasmodium infections for malaria elimination depends on its size, which is generally considered small in low…”
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Plasmodium falciparum msp1, msp2 and glurp allele frequency and diversity in sub-Saharan Africa
Published in Malaria journal (06-04-2011)“…The efficacy of anti-malarial drugs is assessed over a period of 28-63 days (depending on the drugs' residence time) following initiation of treatment in order…”
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Protection against a Malaria Challenge by Sporozoite Inoculation
Published in The New England journal of medicine (30-07-2009)“…The need for an effective malaria vaccine is great, and the current lead strategy undergoing advanced testing is based on the use of the circumsporozoite…”
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Plasmodium falciparum full life cycle and Plasmodium ovale liver stages in humanized mice
Published in Nature communications (24-07-2015)“…Experimental studies of Plasmodium parasites that infect humans are restricted by their host specificity. Humanized mice offer a means to overcome this and…”
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Persistence and activation of malaria hypnozoites in long-term primary hepatocyte cultures
Published in Nature Medicine (01-03-2014)“…Relapses in malaria are caused by hypnozoites, the latent hepatic stage formed by species such as Plasmodium vivax and Plasmodium ovale . Drug discovery…”
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Single-cell RNA sequencing of Plasmodium vivax sporozoites reveals stage- and species-specific transcriptomic signatures
Published in PLoS neglected tropical diseases (01-08-2022)“…Background Plasmodium vivax sporozoites reside in the salivary glands of a mosquito before infecting a human host and causing malaria. Previous…”
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Robust continuous in vitro culture of the Plasmodium cynomolgi erythrocytic stages
Published in Nature communications (12-08-2019)“…The ability to culture pathogenic organisms substantially enhances the quest for fundamental knowledge and the development of vaccines and drugs. Thus, the…”
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Phylogeographic Evidence for 2 Genetically Distinct Zoonotic Plasmodium knowlesi Parasites, Malaysia
Published in Emerging infectious diseases (01-08-2016)“…Infections of humans with the zoonotic simian malaria parasite Plasmodium knowlesi occur throughout Southeast Asia, although most cases have occurred in…”
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Spurious Amplification of a Plasmodium vivax Small-Subunit RNA Gene by Use of Primers Currently Used To Detect P. knowlesi
Published in Journal of Clinical Microbiology (01-12-2009)“…Article Usage Stats Services JCM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Plasmodium falciparum histidine rich protein 2 (pfhrp2): an additional genetic marker suitable for anti-malarial drug efficacy trials
Published in Malaria journal (04-01-2022)“…Genotyping of the three Plasmodium falciparum polymorphic genes, msp1, msp2 and glurp, has been adopted as a standard strategy to distinguish recrudescence…”
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Plasmodium simium: a Brazilian focus of anthropozoonotic vivax malaria?
Published in The Lancet global health (01-10-2017)Get full text
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The evolutionary history of Plasmodium vivax as inferred from mitochondrial genomes: parasite genetic diversity in the Americas
Published in Molecular biology and evolution (01-09-2013)“…Plasmodium vivax is the most prevalent human malaria parasite in the Americas. Previous studies have contrasted the genetic diversity of parasite populations…”
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Timing the origin of human malarias: the lemur puzzle
Published in BMC evolutionary biology (12-10-2011)“…Timing the origin of human malarias has been a focus of great interest. Previous studies on the mitochondrial genome concluded that Plasmodium in primates,…”
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A reliable ex vivo invasion assay of human reticulocytes by Plasmodium vivax
Published in Blood (29-09-2011)“…Currently, there are no reliable RBC invasion assays to guide the discovery of vaccines against Plasmodium vivax, the most prevalent malaria parasite in Asia…”
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On the diversity of malaria parasites in African apes and the origin of Plasmodium falciparum from Bonobos
Published in PLoS pathogens (01-02-2010)“…The origin of Plasmodium falciparum, the etiological agent of the most dangerous forms of human malaria, remains controversial. Although investigations of…”
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Genetic Spatiotemporal Anatomy of Plasmodium vivax Malaria Episodes in Greece, 2009-2013
Published in Emerging infectious diseases (01-03-2018)“…An influx of immigrants is contributing to the reemergence of Plasmodium vivax malaria in Greece; 1 persistent focus of transmission is in Laconia,…”
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