Search Results - "Snijders, Kirsten"

Reconstruction of the mouse extrahepatic biliary tree using primary human extrahepatic cholangiocyte organoids by Sampaziotis, Fotios, Justin, Alexander W, Tysoe, Olivia C, Sawiak, Stephen, Godfrey, Edmund M, Upponi, Sara S, Gieseck, Richard L, de Brito, Miguel Cardoso, Berntsen, Natalie Lie, Gómez-Vázquez, María J, Ortmann, Daniel, Yiangou, Loukia, Ross, Alexander, Bargehr, Johannes, Bertero, Alessandro, Zonneveld, Mariëlle C F, Pedersen, Marianne T, Pawlowski, Matthias, Valestrand, Laura, Madrigal, Pedro, Georgakopoulos, Nikitas, Pirmadjid, Negar, Skeldon, Gregor M, Casey, John, Shu, Wenmiao, Materek, Paulina M, Snijders, Kirsten E, Brown, Stephanie E, Rimland, Casey A, Simonic, Ingrid, Davies, Susan E, Jensen, Kim B, Zilbauer, Matthias, Gelson, William T H, Alexander, Graeme J, Sinha, Sanjay, Hannan, Nicholas R F, Wynn, Thomas A, Karlsen, Tom H, Melum, Espen, Markaki, Athina E, Saeb-Parsy, Kourosh, Vallier, Ludovic

“…Repair of defects in the common bile duct is hampered by a lack of healthy donor tissue. Developing human extrahepatic cholangiocyte organoids and testing them…”
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Genome editing reveals a role for OCT4 in human embryogenesis by Fogarty, Norah M. E., McCarthy, Afshan, Snijders, Kirsten E., Powell, Benjamin E., Kubikova, Nada, Blakeley, Paul, Lea, Rebecca, Elder, Kay, Wamaitha, Sissy E., Kim, Daesik, Maciulyte, Valdone, Kleinjung, Jens, Kim, Jin-Soo, Wells, Dagan, Vallier, Ludovic, Bertero, Alessandro, Turner, James M. A., Niakan, Kathy K.

“…Despite their fundamental biological and clinical importance, the molecular mechanisms that regulate the first cell fate decisions in the human embryo are not…”
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Manipulating and studying gene function in human pluripotent stem cell models by Balmas, Elisa, Sozza, Federica, Bottini, Sveva, Ratto, Maria Luisa, Savorè, Giulia, Becca, Silvia, Snijders, Kirsten E, Bertero, Alessandro

“…Human pluripotent stem cells (hPSCs) are uniquely suited to study human development and disease, and promise to revolutionize regenerative medicine. These…”
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Conditional Gene Knockout in Human Cells with Inducible CRISPR/Cas9 by Snijders, Kirsten E, Cooper, James D, Vallier, Ludovic, Bertero, Alessandro

“…The advent of the easily programmable and efficient CRISPR/Cas9 nuclease system has revolutionized genetic engineering. While conventional gene knockout…”
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Integration of temporal single cell cellular stress response activity with logic-ODE modeling reveals activation of ATF4-CHOP axis as a critical predictor of drug-induced liver injury by Wijaya, Lukas Surya, Trairatphisan, Panuwat, Gabor, Attila, Niemeijer, Marije, Keet, Jason, Alcalà Morera, Ariadna, Snijders, Kirsten E., Wink, Steven, Yang, Huan, Schildknecht, Stefan, Stevens, James L., Bouwman, Peter, Kamp, Hennicke, Hengstler, Jan, Beltman, Joost, Leist, Marcel, Le Dévédec, Sylvia, Saez-Rodriguez, Julio, van de Water, Bob

“…[Display omitted] Drug-induced liver injury (DILI) is the most prevalent adversity encountered in drug development and clinical settings leading to urgent…”
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Optimized inducible shRNA and CRISPR/Cas9 platforms for in vitro studies of human development using hPSCs by Bertero, Alessandro, Pawlowski, Matthias, Ortmann, Daniel, Snijders, Kirsten, Yiangou, Loukia, Cardoso de Brito, Miguel, Brown, Stephanie, Bernard, William G, Cooper, James D, Giacomelli, Elisa, Gambardella, Laure, Hannan, Nicholas R F, Iyer, Dharini, Sampaziotis, Fotios, Serrano, Felipe, Zonneveld, Mariëlle C F, Sinha, Sanjay, Kotter, Mark, Vallier, Ludovic

“…Inducible loss of gene function experiments are necessary to uncover mechanisms underlying development, physiology and disease. However, current methods are…”
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Fluorescent tagging of endogenous Heme oxygenase-1 in human induced pluripotent stem cells for high content imaging of oxidative stress in various differentiated lineages by Snijders, Kirsten E., Fehér, Anita, Táncos, Zsuzsanna, Bock, István, Téglási, Annamária, van den Berk, Linda, Niemeijer, Marije, Bouwman, Peter, Le Dévédec, Sylvia E., Moné, Martijn J., Van Rossom, Rob, Kumar, Manoj, Wilmes, Anja, Jennings, Paul, Verfaillie, Catherine M., Kobolák, Julianna, ter Braak, Bas, Dinnyés, András, van de Water, Bob

“…Tagging of endogenous stress response genes can provide valuable in vitro models for chemical safety assessment. Here, we present the generation and…”
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Protectiveness of NAM-based hazard assessment – which testing scope is required? by Zobl, Walter, Bitsch, Annette, Blum, Jonathan, Boei, Jan J.W.A, Capinha, Liliana, Carta, Giada, Castell, Jose V, Davoli, Enrico, Drake, Christina, Fisher, Ciaran P, Heldring, Muriel M, Islam, Barira, Jennings, Paul, Leist, Marcel, Pellegrino-Coppola, Damiano, Schimming, Johannes P, Snijders, Kirsten E, Tolosa, Laia, van de Water, Bob, van Vugt-Lussenburg, Barbara M.A, Walker, Paul, Wehr, Matthias M, Wijaya, Lukas S, Escher, Sylvia E

“…Hazard assessment requires toxicity tests to allow deriving protective points of departure (PoDs) for risk assessment irrespective of a compound's mode of…”
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Erratum: Genome editing reveals a role for OCT4 in human embryogenesis by Fogarty, Norah M. E., McCarthy, Afshan, Snijders, Kirsten E., Powell, Benjamin E., Kubikova, Nada, Blakeley, Paul, Lea, Rebecca, Elder, Kay, Wamaitha, Sissy E., Kim, Daesik, Maciulyte, Valdone, Kleinjung, Jens, Kim, Jin-Soo, Wells, Dagan, Vallier, Ludovic, Bertero, Alessandro, Turner, James M. A., Niakan, Kathy K.

“…Nature 550, 67–73 (2017); doi:10.1038/nature24033 In this Article, the received date appeared wrongly in the advance online publication (AOP) version as 12…”
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Refined home-brew media for cost-effective, weekend-free hiPSC culture and genetic engineering by Truszkowski, Lukasz, Bottini, Sveva, Bianchi, Sara, Bell, Helen, Becca, Silvia, Savorè, Giulia, Snijders, Kirsten E, Sozza, Federica, Rubinetto, Cristina, Ferrara, Luana, Balmas, Elisa, Elton, Catherine, Bertero, Alessandro

“…Background Cost-effective, practical, and reproducible culture of human induced pluripotent stem cells (hiPSCs) is required for both basic and translational…”
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In Vivo and in Vitro Applications of Biospectroscopy: Potential Use as a Diagnostic Tool Which Can Provide Insights into Cell Cycle Dependent Proliferation by Snijders, Kirsten Esmee

“…Biospectroscopy and its applications characterise in vitro and in vivo cells with abnormal proliferation capacities. Proliferation of endometrial tissues in…”
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Underlying and Extended Data for Refined Home-Brew Media for Cost-Effective, Weekend-Free hiPSC Culture and Genetic Engineering by Truszkowski, Lukasz, Bottini, Sveva, Bianchi, Sara, Bell, Helen, Savorè, Giulia, Snijders, Kirsten E., Sozza, Federica, Rubinetto, Cristina, Ferrera, Luana, Balmas, Elisa, Elton, Catherine, Bertero, Alessandro

“…Extended Data and raw data for the manuscript "Refined home-brew media for cost-effective, weekend-free hiPSC culture and genetic engineering" Extended Data 1…”
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