Search Results - "Snibson, K. J."

Airway remodelling and inflammation in sheep lungs after chronic airway challenge with house dust mite by Snibson, K. J., Bischof, R. J., Slocombe, R. F., Meeusen, E. N.

“…Summary Background Remodelling of airway walls is a significant morbidity factor in patients suffering from chronic asthma. The relationship between airway…”
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Pulmonary delivery of ISCOMATRIX influenza vaccine induces both systemic and mucosal immunity with antigen dose sparing by Wee, J L K, Scheerlinck, J-P Y, Snibson, K J, Edwards, S, Pearse, M, Quinn, C, Sutton, P

“…Using a large animal model, we evaluated whether delivery of influenza vaccine via its mucosal site of infection could improve vaccine effectiveness…”
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Hepatocellular kinetics and the expression of growth hormone (GH) in the livers and liver tumours of GH-transgenic mice by Snibson, K.J

“…Although it is well known that transgenic mice that overexpress growth hormone (GH) frequently develop liver tumours, the precise nature of the relationship…”
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Allelic variation of ovine MHC class II DQA1 and DQA2 genes by Snibson, K. J., Maddox, J. F., Fabb, S. A., Brandon, M. R.

“…In the present study we characterize allelic variation of polymorphic OLA‐DQA1 and OLA‐DQA2 genes in sheep. To achieve this, PCR primers were designed to…”
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Comparison of intrahepatic lymphocytes from normal and growth hormone transgenic mice with chronic hepatitis and liver cancer by HARDY, C. L., BHATHAL, P. S., SNIBSON, K. J., ADAMS, T. E.

“…SUMMARY Mice expressing an ovine growth hormone–mouse metallothionein promoter fusion gene (METoGH mice) develop chronic hepatitis which becomes progressively…”
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Methylation and expression of a metallothionein promoter ovine growth hormone fusion gene (MToGH1) in transgenic mice by SNIBSON, K. J, WOODCOCK, D, ORIAN, J. M, BRANDON, M. R, ADAMS, T. E

“…We have examined transgene methylation in the DNA from the livers of a pedigree of mice carrying three copies of an integrated MToGH1 transgene. Utilizing the…”
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Effects of implantation and early pregnancy on the expression of cytokines and vascular surface molecules in the sheep endometrium by Rahman, Abu Nasar Md. Aminoor, Snibson, Kenneth J., Lee, Chee Seong, Meeusen, Els N.T.

“…Successful implantation is a highly coordinated process involving changes in cytokines, adhesion molecules, hormones, enzymes and growth factors. This study…”
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Ultrastructural localization and gradient of activity of alkaline phosphatase activity during rodent odontogenesis by Orams, H J, Snibson, K J

“…The ultrastructural localization and gradient of activity of alkaline phosphatase were studied with respect to cell differentiation, matrix synthesis, and…”
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Biomedical applications of sheep models: from asthma to vaccines by Scheerlinck, Jean-Pierre Y, Snibson, Kenneth J, Bowles, Vernon M, Sutton, Philip

“…Although rodent models are very popular for scientific studies, it is becoming more evident that large animal models can provide unique opportunities for…”
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High, persistent hepatocellular proliferation and apoptosis precede hepatocarcinogenesis in growth hormone transgenic mice by Snibson, Kenneth J., Bhathal, Prithi S., Hardy, Charles L., Brandon, Malcolm R., Adams, Timothy E.

“…: Aims/Background: Growth hormone (GH) transgenic mice are known to develop hepatocellular adenomas and carcinomas. In order to understand more about…”
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D29 FRESH PERSPECTIVES ON AIRWAY REMODELING: FROM THE ROCKY MOUNTAIN HIGH TO COUNTRY ROADS: The Effects Of Tumstatin On Vascular Remodeling In An Experimental Sheep Model Of Chronic Asthma by Snibson, K J, Van Der Velden, J, Harkness, L M, Barker, D, Koumoundouros, E, Organ, L, Ugalde, C, Burgess, J K

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Thoracic duct cannulation without thoracotomy in sheep: A method for accessing efferent lymph from the lung by Yen, Hung-Hsun, Wee, Janet L.-K., Snibson, Kenneth J., Scheerlinck, Jean-Pierre Y.

“…We have developed and validated a novel method to access efferent lymph draining the lung and gut of sheep. In this model, efferent lymph derived from the lung…”
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Erratum: Pulmonary delivery of ISCOMATRIX influenza vaccine induces both systemic and mucosal immunity with antigen dose sparing by Wee, J L J, Scheerlinck, J-P Y, Snibson, K J, Edwards, S, Pearse, M, Quinn, C, Sutton, P

“…Mucosal Immunology (2008) 1, 489–496; doi:10.1038/mi.2008.59 For the above referenced article, there was a typesetting error made to the x axis labels in…”
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Overexpressed growth hormone (GH) synergistically promotes carcinogen-initiated liver tumour growth by promoting cellular proliferation in emerging hepatocellular neoplasms in female and male GH-transgenic mice by Snibson, Kenneth J., Bhathal, Prithi S., Adams, Timothy E.

“…: Background/Aims: Growth hormone (GH), when overexpressed in male and female GH‐transgenic mice, is known to induce liver tumours within 1 year. This study…”
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Adaptive control of airway tone in sheep that have asthma-like responses by Koumoundouros, E., Snibson, K. J., Mareels, I. M.

“…A model reference, direct adaptive control model has been identified and is able to track airway tone from sheep that have asthma-like responses. This closed…”
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Measurement and impact of remodeling in the lung: airway neovascularization in asthma by Bischof, Robert J, Bourke, Jane E, Hirst, Stuart J, Meeusen, Els N T, Snibson, Kenneth J, Van Der Velden, Joanne

“…Expansion of the airway wall vascular compartment has recently been established as a feature of asthma involving both enlargement of existing vascular…”
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