Search Results - "Sng, Christopher C T"

Untranslated regions (UTRs) are a potential novel source of neoantigens for personalised immunotherapy by Sng, Christopher C T, Kallor, Ashwin Adrian, Simpson, Benjamin S, Bedran, Georges, Alfaro, Javier, Litchfield, Kevin

“…Neoantigens, mutated tumour-specific antigens, are key targets of anti-tumour immunity during checkpoint inhibitor (CPI) treatment. Their identification is…”
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Cancer History and Systemic Anti-Cancer Therapy Independently Predict COVID-19 Mortality: A UK Tertiary Hospital Experience by Sng, Christopher C T, Wong, Yien Ning Sophia, Wu, Anjui, Ottaviani, Diego, Chopra, Neha, Galazi, Myria, Benafif, Sarah, Soosaipillai, Gehan, Roylance, Rebecca, Lee, Alvin J X, Shaw, Heather

“…The COVID-19 pandemic remains a pressing concern to patients with cancer as countries enter the second peak of the pandemic and beyond. It remains unclear…”
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A type III complement factor D deficiency: Structural insights for inhibition of the alternative pathway by Sng, Christopher C.T., O'Byrne, Sorcha, Prigozhin, Daniil M., Bauer, Matthias R., Harvey, Jennifer C., Ruhle, Michelle, Challis, Ben G., Lear, Sara, Roberts, Lee D., Workman, Sarita, Janowitz, Tobias, Magiera, Lukasz, Doffinger, Rainer, Buckland, Matthew S., Jodrell, Duncan J., Semple, Robert K., Wilson, Timothy J., Modis, Yorgo, Thaventhiran, James E.D.

“…Conversely, in both mutant simulations, the distance remained larger, consistent with His41 pointing away from the active site. [...]in addition to disruption…”
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Presenting Features and Early Mortality from SARS-CoV-2 Infection in Cancer Patients during the Initial Stage of the COVID-19 Pandemic in Europe by Pinato, David J, Lee, Alvin J X, Biello, Federica, Seguí, Elia, Aguilar-Company, Juan, Carbó, Anna, Bruna, Riccardo, Bower, Mark, Rizzo, Gianpiero, Benafif, Sarah, Carmona, Carme, Chopra, Neha, Cruz, Claudia Andrea, D'Avanzo, Francesca, Evans, Joanne S, Galazi, Myria, Garcia-Fructuoso, Isabel, Dalla Pria, Alessia, Newsom-Davis, Thomas, Ottaviani, Diego, Patriarca, Andrea, Reyes, Roxana, Sharkey, Rachel, Sng, Christopher C T, Wong, Yien Ning Sophia, Ferrante, Daniela, Scotti, Lorenza, Avanzi, Gian Carlo, Bellan, Mattia, Castello, Luigi Mario, Marco-Hernández, Javier, Mollà, Meritxell, Pirisi, Mario, Ruiz-Camps, Isabel, Sainaghi, Pier Paolo, Gaidano, Gianluca, Brunet, Joan, Tabernero, Josep, Prat, Aleix, Gennari, Alessandra

“…We describe the outcomes in cancer patients during the initial outbreak of the COVID-19 in Europe from the retrospective, multi-center observational OnCovid…”
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Systemic Anti-Cancer Therapy and Metastatic Cancer Are Independent Mortality Risk Factors during Two UK Waves of the COVID-19 Pandemic at University College London Hospital by Wong, Yien Ning Sophia, Sng, Christopher C T, Ottaviani, Diego, Patel, Grisma, Chowdhury, Amani, Earnshaw, Irina, Sinclair, Alasdair, Merry, Eve, Wu, Anjui, Galazi, Myria, Benafif, Sarah, Soosaipillai, Gehan, Chopra, Neha, Roylance, Rebecca, Shaw, Heather, Lee, Alvin J X

“…An increased mortality risk was observed in patients with cancer during the first wave of COVID-19. Here, we describe determinants of mortality in patients…”
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Vaccination against SARS-CoV-2 protects from morbidity, mortality and sequelae from COVID19 in patients with cancer by Pinato, David J., Ferrante, Daniela, Aguilar-Company, Juan, Bower, Mark, Sureda, Anna, Bertuzzi, Alexia, Brunet, Joan, Pedrazzoli, Paolo, Biello, Federica, Lee, Alvin J.X., Sng, Christopher C.T., Liñan, Raquel, Carmona-García, M.Carmen, Sharkey, Rachel, Eremiev, Simeon, Rizzo, Gianpiero, Bain, Hamish DC, Yu, Tamara, Cruz, Claudia A., Saoudi-Gonzalez, Nadia, Roldán, Elisa, Zoratto, Federica, Bruna, Riccardo, Patriarca, Andrea, Martinez-Vila, Clara, Berardi, Rossana, Mazzoni, Francesca, Santoro, Armando, Delfanti, Sara, Queirolo, Paola, Prat, Aleix, Tabernero, Josep, Cortellini, Alessio, Pinato, David J., Swallow, Judith, Cortellini, Alessio, Hanbury, Georgina, Chung, Chris, Ottaviani, Diego, Lee, Alvin JX, Yu, Tamara, Shawe-Taylor, Marianne, Bain, Hamish DC, Sinclair, Alasdair, Belessiotis, Katherine, Bawany, Samira, Newsom-Davis, Thomas, Dolly, Saorise, Sita-Lumsde, Ailsa, Apthorp, Eleanor, Jones, Eleanor, Van Hemelrijck, Mieke, Russell, Beth, Diamantis, Nikolaos, Mukherjee, Uma, Loizidou, Angela, Piccart, Martine, Cruz, Claudia A., Reyes, Roxana, Segui, Elia, Marco-Hernández, Javier, Viladot, Margarita, Aguilar-Company, Juan, Ruiz-Camps, Isabel, Fox, Laura, Garcia Illescas, David, Saoudi, Nadia, Carmona Garcia, MCarmen, Fort-Culillas, Robert, Liñan, Raquel, Harbeck, Nadia, Wuerstlein, Rachel, Mahner, Sven, Plaja, Andrea, Cucurull, Marc, Salazar, Ramon, Gennari, Alessandra, D’Avanzo, Francesca, Bruna, Riccardo, Pedrazzoli, Paolo, Bertuzzi, Alexia, Rossi, Sabrina, Marrari, Andrea, Rimassa, Lorenza, Fusco, Vittorio, Delfanti, Sara, Maconi, Antonio, Tondini, Carlo, Fotia, Vittoria, Provenzano, Salvatore, Generali, Daniele, Baggi, Alice, Porzio, Giampiero, Queirolo, Paola, Giusti, Raffaele, Mazzoni, Francesca, Zoratto, Federica, Cantini, Luca, Guida, Annalisa, Martinez-Vila, Clara

“…Although SARS-CoV-2 vaccines immunogenicity in patients with cancer has been investigated, whether they can significantly improve the severity of COVID-19 in…”
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Abstract S01-03: The acute phase response identifies cancer patients with adverse outcomes from SARS-CoV-2 infection as quantified by the OnCovid Inflammatory Score by Dettorre, Gino M., Dolly, Saoirse, Loizidou, Angela, Chester, John, Jackson, Amanda, Mukherjee, Uma, Zambelli, Alberto, Aguilar-Company, Juan, Bower, Mark, Sng, Christopher C. T., Salazar, Ramon, Bertuzzi, Alexia, Brunet, Joan, Mesia, Ricard, Sita-Lumsden, Ailsa, Seguí, Elia, Biello, Federica, Generali, Daniele, Grisanti, Salvatore, Seeva, Pavetha, Rizzo, Gianpiero, Libertini, Michela, Maconi, Antonio, Moss, Charlotte, Russell, Beth, Tabernero, Josep, Harbeck, Nadia, Vincenzi, Bruno, Bertulli, Rossella, Ottaviani, Diego, Marrari, Andrea, Carmona-García, M. Carmen, Chopra, Neha, Tondini, Carlo, Mirallas, Oriol, Tovazzi, Valeria, Fotia, Vittoria, Cruz, Claudia A., Saoudi-Gonzalez, Nadia, Felip, Eudald, Scotti, Lorenza, Lee, Alvin J. X., Newsom-Davis, Thomas, Patriarca, Andrea, Rimassa, Lorenza, Santoro, Armando, Gennari, Alessandra, Van Hemelrijck, Mieke, Diamantis, Nikolaos, Pinato, David J.

“…Abstract We sought to determine parameters of the acute phase response, a feature of innate immunity activated by infectious noxae and cancer, deranged by…”
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Systemic pro-inflammatory response identifies patients with cancer with adverse outcomes from SARS-CoV-2 infection: the OnCovid Inflammatory Score by Dettorre, Gino M, Dolly, Saoirse, Loizidou, Angela, Chester, John, Jackson, Amanda, Mukherjee, Uma, Zambelli, Alberto, Aguilar-Company, Juan, Bower, Mark, Sng, Christopher C T, Salazar, Ramon, Bertuzzi, Alexia, Brunet, Joan, Mesia, Ricard, Sita-Lumsden, Ailsa, Seguí, Elia, Biello, Federica, Generali, Daniele, Grisanti, Salvatore, Seeva, Pavetha, Rizzo, Gianpiero, Libertini, Michela, Maconi, Antonio, Moss, Charlotte, Russell, Beth, Harbeck, Nadia, Vincenzi, Bruno, Bertulli, Rossella, Ottaviani, Diego, Liñan, Raquel, Marrari, Andrea, Carmona-García, M Carmen, Chopra, Neha, Tondini, Carlo Alberto, Mirallas, Oriol, Tovazzi, Valeria, Fotia, Vittoria, Cruz, Claudia Andrea, Saoudi-Gonzalez, Nadia, Felip, Eudald, Roqué, Ariadna, Lee, Alvin J X, Newsom-Davis, Tom, García-Illescas, David, Reyes, Roxana, Wong, Yien Ning Sophia, Ferrante, Daniela, Scotti, Lorenza, Marco-Hernández, Javier, Ruiz-Camps, Isabel, Patriarca, Andrea, Rimassa, Lorenza, Chiudinelli, Lorenzo, Franchi, Michela, Santoro, Armando, Prat, Aleix, Gennari, Alessandra, Van Hemelrijck, Mieke, Tabernero, Josep, Diamantis, Nikolaos, Pinato, David J

“…BackgroundPatients with cancer are particularly susceptible to SARS-CoV-2 infection. The systemic inflammatory response is a pathogenic mechanism shared by…”
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Determinants of enhanced vulnerability to coronavirus disease 2019 in UK patients with cancer: a European study by Pinato, David J., Scotti, Lorenza, Gennari, Alessandra, Colomba-Blameble, Emeline, Dolly, Saoirse, Loizidou, Angela, Chester, John, Mukherjee, Uma, Zambelli, Alberto, Aguilar-Company, Juan, Bower, Mark, Galazi, Myria, Salazar, Ramon, Bertuzzi, Alexia, Brunet, Joan, Mesia, Ricard, Sita-Lumsden, Ailsa, Colomba, Johann, Pommeret, Fanny, Seguí, Elia, Biello, Federica, Generali, Daniele, Grisanti, Salvatore, Rizzo, Gianpiero, Libertini, Michela, Moss, Charlotte, Evans, Joanne S., Russell, Beth, Wuerstlein, Rachel, Vincenzi, Bruno, Bertulli, Rossella, Ottaviani, Diego, Liñan, Raquel, Marrari, Andrea, Carmona-García, M.C., Sng, Christopher. C.T., Tondini, Carlo, Mirallas, Oriol, Tovazzi, Valeria, Fotia, Vittoria, Cruz, Claudia A., Saoudi-Gonzalez, Nadia, Felip, Eudald, R. Lloveras, Ariadna, Lee, Alvin. J.X., Newsom-Davis, Thomas, Sharkey, Rachel, Chung, Chris, García-Illescas, David, Reyes, Roxana, Sophia Wong, Yien N., Ferrante, Daniela, Marco-Hernández, Javier, Ruiz-Camps, Isabel, Gaidano, Gianluca, Patriarca, Andrea, Sureda, Anna, Martinez-Vila, Clara, Sanchez de Torre, Ana, Rimassa, Lorenza, Chiudinelli, Lorenzo, Franchi, Michela, Krengli, Marco, Santoro, Armando, Prat, Aleix, Tabernero, Josep, V. Hemelrijck, Mieke, Diamantis, Nikolaos, Cortellini, Alessio

“…Despite high contagiousness and rapid spread, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has led to heterogeneous outcomes across affected…”
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Specialist palliative and end-of-life care for patients with cancer and SARS-CoV-2 infection: a European perspective by Soosaipillai, Gehan, Wu, Anjui, Dettorre, Gino M, Diamantis, Nikolaos, Chester, John, Moss, Charlotte, Aguilar-Company, Juan, Bower, Mark, Sng, Christopher CT, Salazar, Ramon, Brunet, Joan, Jones, Eleanor, Mesia, Ricard, Jackson, Amanda, Mukherjee, Uma, Sita-Lumsden, Ailsa, Seguí, Elia, Ottaviani, Diego, Carbó, Anna, Benafif, Sarah, Würstlein, Rachel, Carmona, Carme, Chopra, Neha, Cruz, Claudia Andrea, Swallow, Judith, Saoudi, Nadia, Felip, Eudald, Galazi, Myria, Garcia-Fructuoso, Isabel, Lee, Alvin J. X., Newsom-Davis, Thomas, Wong, Yien Ning Sophia, Sureda, Anna, Maluquer, Clara, Ruiz-Camps, Isabel, Cabirta, Alba, Prat, Aleix, Loizidou, Angela, Gennari, Alessandra, Ferrante, Daniela, Tabernero, Josep, Russell, Beth, Van Hemelrijck, Mieke, Dolly, Saoirse, Hulbert-Williams, Nicholas J, Pinato, David J, Mollà, Meritxell, Reyes, Roxana, Marco-Hernández, Javier, Bruna, Riccardo, Biello, Federica, Patriarca, Andrea, Zambelli, Alberto, Tondini, Carlo, Fotia, Vittoria, Chiudinelli, Lorenzo, Franchi, Michela, Generali, Daniele, Grisanti, Salvatore, Tovazzi, Valeria, Bertuzzi, Alexia, Marrari, Andrea, Seeva, Pavetha, Dileo, Palma, Rizzo, Gianpiero, Libertini, Michela, Maconi, Antonio, Betti, Marta, Provenzano, Salvatore, Harbeck, Nadia, Vincenzi, Bruno, Bertulli, Rossella, Liñan, Raquel, Roqué, Ariadna, Mirallas, Oriol, García-Illescas, David, Scotti, Lorenza, Dalla Pria, Alessia, D’Avanzo, Francesca, Martinez, Maria, Evans, Joanne S, Sharkey, Rachel, Rimassa, Lorenza, Santoro, Armando, Gaidano, Gianluca, Izuzquiza, Macarena

“…Background: Specialist palliative care team (SPCT) involvement has been shown to improve symptom control and end-of-life care for patients with cancer, but…”
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