Search Results - "Snell, P"

Beyond 'find and fix': improving quality and safety through resilient healthcare systems by Anderson, J E, Ross, A J, Back, J, Duncan, M, Snell, P, Hopper, A, Jaye, P

“…The aim was to develop a method based on resilient healthcare principles to proactively identify system vulnerabilities and quality improvement interventions…”
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Mapping the summer 2017 surface water circulation of Picton Bay, ON by Shore, J. A., Snell, P.

“…Abstract On March 24, 2017, a fuel spill from a partially submerged barge in Picton Bay contaminated the source water for the drinking water supply of the…”
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A Novel Approach to ICU Survivor Care: A Population Health Quality Improvement Project by Snell, Kenneth P., Beiter, Cynthia L., Hall, Erin L., Junod, Anthony S., Wilson, Bradley J., Lepone, Daniel K., McIntyre, Jeremy R., Swartz, Danielle Phelps, Berger, Andrea L., Kirchner, H. Lester, Tomcavage, Janet F., Korzick, Karen A.

“…OBJECTIVES:Deliver a novel interdisciplinary care process for ICU survivor care and their primary family caregivers, and assess mortality, readmission rates,…”
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Structural Basis for the Autoinhibition and STI-571 Inhibition of c-Kit Tyrosine Kinase by Mol, Clifford D, Dougan, Douglas R, Schneider, Thomas R, Skene, Robert J, Kraus, Michelle L, Scheibe, Daniel N, Snell, Gyorgy P, Zou, Hua, Sang, Bi-Ching, Wilson, Keith P

“…The activity of the c-Kit receptor protein-tyrosine kinase is tightly regulated in normal cells, whereas deregulated c-Kit kinase activity is implicated in the…”
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Implementing resilience engineering for healthcare quality improvement using the CARE model: a feasibility study protocol by Anderson, J E, Ross, A J, Back, J, Duncan, M, Snell, P, Walsh, K, Jaye, P

“…Resilience engineering (RE) is an emerging perspective on safety in complex adaptive systems that emphasises how outcomes emerge from the complexity of the…”
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Rice varieties with resistance to multiple races of Magnaporthe oryzae offer opportunities to manage rice blast in Australia by Fang, X., Snell, P., Barbetti, M.J., Lanoiselet, V.

“…Rice blast caused by Magnaporthe oryzae is the most destructive disease of rice worldwide. Development of resistant varieties is considered as the most…”
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Design and Synthesis of Potent Inhibitor of Apoptosis (IAP) Proteins Antagonists Bearing an Octahydropyrrolo[1,2‑a]pyrazine Scaffold as a Novel Proline Mimetic by Hashimoto, Kentaro, Saito, Bunnai, Miyamoto, Naoki, Oguro, Yuya, Tomita, Daisuke, Shiokawa, Zenyu, Asano, Moriteru, Kakei, Hiroyuki, Taya, Naohiro, Kawasaki, Masanori, Sumi, Hiroyuki, Yabuki, Masato, Iwai, Kenichi, Yoshida, Sei, Yoshimatsu, Mie, Aoyama, Kazunobu, Kosugi, Yohei, Kojima, Takashi, Morishita, Nao, Dougan, Douglas R, Snell, Gyorgy P, Imamura, Shinichi, Ishikawa, Tomoyasu

“…To develop novel inhibitor of apoptosis (IAP) proteins antagonists, we designed a bicyclic octahydropyrrolo[1,2-a]pyrazine scaffold as a novel proline…”
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QTL controlling low temperature induced spikelet sterility at booting stage in rice by Ye, C, Fukai, S, Godwin, I. D, Koh, H, Reinke, R, Zhou, Y, Lambrides, C, Jiang, W, Snell, P, Redoña, E

“…Low temperature is a major abiotic stress for rice cultivation, causing serious yield loss in many countries. To identify QTL controlling low temperature…”
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Structural and Kinetic Analysis of the Substrate Specificity of Human Fibroblast Activation Protein α by Aertgeerts, Kathleen, Levin, Irena, Shi, Lihong, Snell, Gyorgy P., Jennings, Andy, Prasad, G. Sridhar, Zhang, Yanming, Kraus, Michelle L., Salakian, Shant, Sridhar, Vandana, Wijnands, Robert, Tennant, Mike G.

“…Fibroblast activation protein α (FAPα) is highly expressed in epithelial cancers and has been implicated in extracellular matrix remodeling, tumor growth, and…”
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Risk factors for active trachoma in The Gambia by Harding-Esch, E.M., Edwards, T., Sillah, A., Sarr-Sissoho, I., Aryee, E.A., Snell, P., Holland, M.J., Mabey, D.C., Bailey, R.L.

“…Trachoma has been endemic in The Gambia for decades but national surveys indicate that the prevalence is falling. Risk factor data can help guide trachoma…”
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Discovery of [cis-3-({(5R)‑5-[(7-Fluoro-1,1-dimethyl-2,3-dihydro‑1H‑inden-5-yl)carbamoyl]-2-methoxy-7,8-dihydro-1,6-naphthyridin-6(5H)‑yl}carbonyl)­cyclobutyl]­acetic Acid (TAK-828F) as a Potent, Selective, and Orally Available Novel Retinoic Acid Receptor-Related Orphan Receptor γt Inverse Agonist by Kono, Mitsunori, Ochida, Atsuko, Oda, Tsuneo, Imada, Takashi, Banno, Yoshihiro, Taya, Naohiro, Masada, Shinichi, Kawamoto, Tetsuji, Yonemori, Kazuko, Nara, Yoshi, Fukase, Yoshiyuki, Yukawa, Tomoya, Tokuhara, Hidekazu, Skene, Robert, Sang, Bi-Ching, Hoffman, Isaac D, Snell, Gyorgy P, Uga, Keiko, Shibata, Akira, Igaki, Keiko, Nakamura, Yoshiki, Nakagawa, Hideyuki, Tsuchimori, Noboru, Yamasaki, Masashi, Shirai, Junya, Yamamoto, Satoshi

“…A series of tetrahydro­naphthyridine derivatives as novel RORγt inverse agonists were designed and synthesized. We reduced the lipophilicity of…”
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Self-medication after caesarean section by Geoghegan, J, Snell, P, Moore, P

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An exploratory study in the UK of the effectiveness of three different pain management regimens for post-caesarean section women by Snell, Pamela, Hicks, Carolyn

“…to compare the effects of three types of analgesic administration after elective caesarean section on a number of clinical outcome measures. Supplementary aims…”
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DIEP flap customization using Fluobeam® indocyanine green tissue perfusion assessment with large previous abdominal scar by Fallucco, Michael A., Snell, Colin P., Desai, Ankit R.

“…The Fluobeam® is a portable, near-infrared camera that is held and controlled by the surgeon to visualize tissue perfusion using indocyanine green (ICG)…”
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A Forty-Year Follow-Up of the Dallas Bed Rest and Training Study: The Effect of Age on the Cardiovascular Response to Exercise in Men by McGavock, Jonathan M., Hastings, Jeffrey L., Snell, Peter G., McGuire, Darren K., Pacini, Eric L., Levine, Benjamin D., Mitchell, Jere H.

“…Background In 1966, five 20-year-old men underwent a comprehensive physiological evaluation of the capacity for adaptation of the cardiovascular system in…”
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2-{3-[4-(Alkylsulfinyl)phenyl]-1-benzofuran-5-yl}-5-methyl-1,3,4-oxadiazole Derivatives as Novel Inhibitors of Glycogen Synthase Kinase-3β with Good Brain Permeability by Saitoh, Morihisa, Kunitomo, Jun, Kimura, Eiji, Iwashita, Hiroki, Uno, Yumiko, Onishi, Tomohiro, Uchiyama, Noriko, Kawamoto, Tomohiro, Tanaka, Toshimasa, Mol, Clifford D, Dougan, Douglas R, Textor, Garret P, Snell, Gyorgy P, Takizawa, Masayuki, Itoh, Fumio, Kori, Masakuni

“…Glycogen synthase kinase 3β (GSK-3β) inhibition is expected to be a promising therapeutic approach for treating Alzheimer’s disease. Previously we reported a…”
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Identification of Novel, Potent, and Orally Available GCN2 Inhibitors with Type I Half Binding Mode by Fujimoto, Jun, Kurasawa, Osamu, Takagi, Terufumi, Liu, Xin, Banno, Hiroshi, Kojima, Takuto, Asano, Yasutomi, Nakamura, Akito, Nambu, Tadahiro, Hata, Akito, Ishii, Tsuyoshi, Sameshima, Tomoya, Debori, Yasuyuki, Miyamoto, Maki, Klein, Michael G, Tjhen, Richard, Sang, Bi-Ching, Levin, Irena, Lane, Scott Weston, Snell, Gyorgy P, Li, Ke, Kefala, Georgia, Hoffman, Isaac D, Ding, Steve C, Cary, Douglas R, Mizojiri, Ryo

“…General control nonderepressible 2 (GCN2) is a master regulator kinase of amino acid homeostasis and important for cancer survival in the tumor…”
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Highly conserved regulatory elements around the gene may contribute to the maintenance of conserved synteny across human chromosome 7q36.3 by GOODE, D, SNELL, P, SMITH, S, COOKE, J, ELGAR, G

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Design, synthesis and structure–activity relationships of 1,3,4-oxadiazole derivatives as novel inhibitors of glycogen synthase kinase-3β by Saitoh, Morihisa, Kunitomo, Jun, Kimura, Eiji, Hayase, Yoji, Kobayashi, Hiromi, Uchiyama, Noriko, Kawamoto, Tomohiro, Tanaka, Toshimasa, Mol, Clifford D., Dougan, Douglas R., Textor, Garret S., Snell, Gyorgy P., Itoh, Fumio

“…Design, synthesis and structure–activity relationships of novel oxadiazole derivatives as GSK-3β inhibitors are reported. Glycogen synthase kinase-3β (GSK-3β)…”
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144 - An unusual treatment for refractory abdominal distention by Crawford, PT, Stallings, C, Snell, P

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