Search Results - "Sneed, Sydney E"
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Detecting functional connectivity disruptions in a translational pediatric traumatic brain injury porcine model using resting-state and task-based fMRI
Published in Scientific reports (11-06-2021)“…Functional magnetic resonance imaging (fMRI) has significant potential to evaluate changes in brain network activity after traumatic brain injury (TBI) and…”
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Exploring the predictive value of lesion topology on motor function outcomes in a porcine ischemic stroke model
Published in Scientific reports (15-02-2021)“…Harnessing the maximum diagnostic potential of magnetic resonance imaging (MRI) by including stroke lesion location in relation to specific structures that are…”
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Tanshinone IIA-loaded nanoparticles and neural stem cell combination therapy improves gut homeostasis and recovery in a pig ischemic stroke model
Published in Scientific reports (13-02-2023)“…Impaired gut homeostasis is associated with stroke often presenting with leaky gut syndrome and increased gut, brain, and systemic inflammation that further…”
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Fecal microbial transplantation limits neural injury severity and functional deficits in a pediatric piglet traumatic brain injury model
Published in Frontiers in neuroscience (28-09-2023)“…Pediatric traumatic brain injury (TBI) is a leading cause of death and disability in children. Due to bidirectional communication between the brain and gut…”
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Human-Induced Pluripotent Stem Cell-Derived Neural Stem Cell Therapy Limits Tissue Damage and Promotes Tissue Regeneration and Functional Recovery in a Pediatric Piglet Traumatic-Brain-Injury Model
Published in Biomedicines (25-07-2024)“…Traumatic brain injury (TBI) is a leading cause of death and disability in pediatric patients and often results in delayed neural development and altered…”
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White Matter Integrity and Motor Function Disruption Due to Traumatic Brain Injury in Piglets: Impacts on Motor-Related Brain Fibers
Published in Brain sciences (01-03-2024)“…Pediatric traumatic brain injury (TBI) often induces significant disability in patients, including long-term motor deficits. Early detection of injury severity…”
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Magnetic Resonance Imaging and Gait Analysis Indicate Similar Outcomes Between Yucatan and Landrace Porcine Ischemic Stroke Models
Published in Frontiers in neurology (21-01-2021)“…The Stroke Therapy Academic Industry Roundtable (STAIR) has recommended that novel therapeutics be tested in a large animal model with similar anatomy and…”
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Changes in Oral Microbial Diversity in a Piglet Model of Traumatic Brain Injury
Published in Brain sciences (21-08-2022)“…Dynamic changes in the oral microbiome have gained attention due to their potential diagnostic role in neurological diseases such as Alzheimer's disease and…”
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Changes in Oral Microbial Diversity in a Piglet Model of Traumatic Brain Injury
Published in The FASEB journal (01-05-2022)“…The dynamic changes in the oral microbiome in response to disease has led to significant interest in utilizing microbiome analysis as a potential diagnostic…”
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Tanshinone IIA-Loaded Nanoparticle and Neural Stem Cell Therapy Enhances Recovery in a Pig Ischemic Stroke Model
Published in Stem cells translational medicine (21-10-2022)“…Induced pluripotent stem cell-derived neural stem cells (iNSCs) are a multimodal stroke therapeutic that possess neuroprotective, regenerative, and cell…”
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An Adolescent Porcine Model of Voluntary Alcohol Consumption Exhibits Binge Drinking and Motor Deficits in a Two Bottle Choice Test
Published in Alcohol and alcoholism (Oxford) (29-04-2021)“…Abstract Aims Alcohol is the most commonly abused substance leading to significant economic and medical burdens. Pigs are an attractive model for studying…”
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Evaluation of Brain Function Recovery After Traumatic Brain Injury Treatment in a Porcine Model by Cross-Group Temporal–Spatial Correlation Analysis
Published in Neurotrauma reports (01-07-2024)“…Traumatic brain injury (TBI), a significant global health issue, is affecting ∼69 million annually. To better understand TBI’s impact on brain function and…”
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Abstract P763: A Precision Medicine Approach to Intracerebral Stem Cell Transplantation Utilizing Lesion Topology in a Porcine Model of Ischemic Stroke
Published in Stroke (1970) (01-03-2021)“…Despite the devastating global impact of ischemic stroke, there are few Food and Drug Administration (FDA) approved treatments, none of which are capable of…”
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Abstract WMP119: Tanshinone IIa-loaded Nanoparticles And Induced Pluripotent Stem Cell-derived Neural Stem Cell Therapies Enhance Recovery In A Translational Pig Ischemic Stroke Model
Published in Stroke (1970) (01-02-2022)“…Induced pluripotent stem cell-derived neural stem cells (iNSCs) have led to cellular and functional recovery in ischemic stroke models. However, the…”
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