Search Results - "Snedeker, J G"

Misalignment of Total Ankle Components Can Induce High Joint Contact Pressures by Espinosa, N., Walti, M., Favre, P., Snedeker, J.G.

“…A major cause of the limited longevity of total ankle replacements is premature polyethylene component wear, which can be induced by high joint contact…”
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Tendon glycosaminoglycan proteoglycan sidechains promote collagen fibril sliding—AFM observations at the nanoscale by Rigozzi, S, Müller, R, Stemmer, A, Snedeker, J.G

“…Abstract The extracellular matrix of tendon is mainly composed of discontinuous Type-I collagen fibrils and small leucine rich proteoglycans (PG). Macroscopic…”
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FGF2 overrides key pro-fibrotic features of bone marrow stromal cells isolated from Modic type 1 change patients by Heggli, I, Blache, U, Herger, N, Mengis, T, Jaeger, P K, Schuepbach, R, Farshad-Amacker, N, Brunner, F, Snedeker, J G, Farshad, M, Distler, O, Dudli, S

“…Extensive extracellular matrix production and increased cell-matrix adhesion by bone marrow stromal cells (BMSCs) are hallmarks of fibrotic alterations in the…”
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Cytoskeleton reorganization of spreading cells on micro-patterned islands: a functional model by Loosli, Y., Luginbuehl, R., Snedeker, J. G.

“…Predictive numerical models of cellular response to biophysical cues have emerged as a useful quantitative tool for cell biology research. Cellular experiments…”
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Simulation and evaluation of 3D traction force microscopy by Holenstein, C.N., Lendi, C.R., Wili, Nino, Snedeker, J.G.

“…Measuring cell-generated forces by Traction Force Microscopy (TFM) has become a standard tool in cell mechanobiology. Although widely used in two dimensional…”
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Further characterisation of an experimental model of tendinopathy in the horse by Cadby, J. A., David, F., van de Lest, C., Bosch, G., van Weeren, P. R., Snedeker, J. G., van Schie, H. T. M.

“…Summary Reasons for performing study Injuries in energy‐storing tendons are common in both horses and man. The high prevalence of reinjury and the relatively…”
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Strain-rate dependent material properties of the porcine and human kidney capsule by Snedeker, J.G., Niederer, P., Schmidlin, F.R., Farshad, M., Demetropoulos, C.K., Lee, J.B., Yang, K.H.

“…This study was performed to characterize the mechanical properties of the kidney capsular membrane at strain-rates associated with blunt abdominal trauma…”
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The lever arm ratio of the rotator cuff to deltoid muscle explains and predicts pseudoparalysis of the shoulder: the Shoulder Abduction Moment index by Bouaicha, S, Ernstbrunner, L, Jud, L, Meyer, D C, Snedeker, J G, Bachmann, E

“…In patients with a rotator cuff tear, tear pattern and tendon involvement are known risk factors for the development of pseudoparalysis of the shoulder. It…”
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Strain energy density as a rupture criterion for the kidney: impact tests on porcine organs, finite element simulation, and a baseline comparison between human and porcine tissues by Snedeker, J.G., Barbezat, M., Niederer, P., Schmidlin, F.R., Farshad, M.

“…High-velocity (up to 25m/s) impact tests were performed on pig kidneys to characterize failure behavior at deformation rates associated with traumatic injury…”
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Local strain measurement reveals a varied regional dependence of tensile tendon mechanics on glycosaminoglycan content by Rigozzi, S, Müller, R, Snedeker, J.G

“…Abstract Proteoglycans (PG) and their associated glycosaminoglycan (GAG) side chains are known to play a key role in the bearing of compressive loads in…”
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Pull-out strength of patient-specific template-guided vs. free-hand fluoroscopically controlled thoracolumbar pedicle screws: a biomechanical analysis of a randomized cadaveric study by Aichmair, A., Moser, M., Bauer, M. R., Bachmann, E., Snedeker, J. G., Betz, M., Farshad, M.

“…Purpose To assess the pull-out strength of thoracolumbar pedicle screws implanted via either a patient-specific template-guided or conventional free-hand…”
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Collagen fibril morphology and mechanical properties of the Achilles tendon in two inbred mouse strains by Rigozzi, S., Müller, R., Snedeker, J. G.

“…The relationship between collagen fibril morphology and the functional behavior of tendon tissue has been investigated in numerous experimental studies…”
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Mechanical response of individual collagen fibrils in loaded tendon as measured by atomic force microscopy by Rigozzi, S., Stemmer, A., Müller, R., Snedeker, J.G.

“…A precise analysis of the mechanical response of collagen fibrils in tendon tissue is critical to understanding the ultrastructural mechanisms that underlie…”
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Biomechanical consequences of first metatarsal osteotomy in treating hallux valgus by Favre, P, Farine, M, Snedeker, J.G, Maquieira, G.J, Espinosa, N

“…Abstract Background Among the numerous osteotomies for correction of hallux valgus, the modified chevron is known for its good intrinsic stability and the…”
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Numerically bridging lamellipodial and filopodial activity during cell spreading reveals a potentially novel trigger of focal adhesion maturation by Loosli, Y, Vianay, B, Luginbuehl, R, Snedeker, J G

“…We present a novel approach to modeling cell spreading, and use it to reveal a potentially central mechanism regulating focal adhesion maturation in various…”
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An actin length threshold regulates adhesion maturation at the lamellipodium/lamellum interface by Loosli, Y, Labouesse, C, Luginbuehl, R, Meister, J-J, Snedeker, J G, Vianay, B

“…The mechanical coupling between adherent cells and their substrates is a major driver of downstream behavior. This coupling relies on the formation of adhesion…”
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An analytical model for elucidating tendon tissue structure and biomechanical function from in vivo cellular confocal microscopy images by Snedeker, J G, Pelled, G, Zilberman, Y, Ben Arav, A, Huber, E, Müller, R, Gazit, D

“…Fibered confocal laser scanning microscopes have given us the ability to image fluorescently labeled biological structures in vivo and at exceptionally high…”
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Microstructural insight into pedestrian pelvic fracture as assessed by high-resolution computed tomography by Snedeker, J.G., Walz, F.H., Muser, M.H., Schroeder, G., Mueller, T.L., Müller, R.

“…Pelvic and femoral neck bone surface strains were recorded in five full-body human cadaver vehicle–pedestrian impacts. Impacts were performed at 40 km/h using…”
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Kidney Injury: An Experimental Investigation of Blunt Renal Trauma by Schmitt, K -U., Snedeker, J G.

“…BACKGROUND:The abdomen ranks third with regard to injured body regions, and urogenital trauma accounts for up to 10% of all abdominal injuries. Predictive…”
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Comparing the Biomechanical Response of Human and Porcine Kidneys to Blunt Trauma by Schmitt, K -U., Varga, Z, Snedeker, J G.

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