Search Results - "Snape, Matthew"
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COVID-19 in children and young people
Published in Science (American Association for the Advancement of Science) (16-10-2020)“…Children have a low risk of COVID-19 and are disproportionately harmed by precautions The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic…”
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Heterologous prime-boost COVID-19 vaccination: initial reactogenicity data
Published in The Lancet (British edition) (29-05-2021)“…Haematology and biochemistry safety monitoring blood results are also reported from the immunology cohort (100 participants with additional visits), at…”
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Reduced neutralisation of SARS-CoV-2 omicron B.1.1.529 variant by post-immunisation serum
Published in The Lancet (British edition) (15-01-2022)“…According to WHO, SARS-CoV-2 is estimated to have caused 265 million infections and more than 5 million deaths over the past 2 years. First alpha and then…”
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Preventing type 1 diabetes in childhood
Published in Science (American Association for the Advancement of Science) (30-07-2021)“…Type 1 diabetes (T1D) is an autoimmune disease in which the insulin-producing β cells of the pancreas are destroyed by T lymphocytes. Recent studies have…”
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SARS-CoV-2 Variants and Vaccines
Published in The New England journal of medicine (08-07-2021)“…Viral variants of concern may emerge with dangerous resistance to the immunity generated by the current vaccines to prevent coronavirus disease 2019…”
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The burden of respiratory syncytial virus in healthy term-born infants in Europe: a prospective birth cohort study
Published in The lancet respiratory medicine (01-04-2023)“…Respiratory syncytial virus (RSV) is a major cause of hospitalisation in infants. The burden of RSV infection in healthy term infants has not yet been…”
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Economic burden and health-related quality-of-life among infants with respiratory syncytial virus infection: A multi-country prospective cohort study in Europe
Published in Vaccine (17-04-2023)“…•We collected daily data to assess the impact of RSV on infants and caregivers.•RSV quality of life loss was substantial, irrespective of medical…”
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Multicenter, Open-Label, Randomized Phase II Controlled Trial of an Investigational Recombinant Meningococcal Serogroup B Vaccine With and Without Outer Membrane Vesicles, Administered in Infancy
Published in Clinical infectious diseases (15-11-2010)“…Background. In the absence of an efficacious broadly protective vaccine, serogroup B Neisseria meningitidis (MenB) is the leading cause of bacterial meningitis…”
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Pneumococcal conjugate vaccine 13 delivered as one primary and one booster dose (1 + 1) compared with two primary doses and a booster (2 + 1) in UK infants: a multicentre, parallel group randomised controlled trial
Published in The Lancet infectious diseases (01-02-2018)“…Infants in the UK were first offered a pneumococcal conjugate vaccine (PCV7) in 2006, given at 2 and 4 months of age and a booster dose at 13 months (2 + 1…”
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An increase in accident and emergency presentations for adverse events following immunisation after introduction of the group B meningococcal vaccine: an observational study
Published in Archives of disease in childhood (01-10-2017)“…ObjectivesTo determine whether the introduction of the capsular group B meningococcal vaccine (4CMenB) in the UK has increased presentations of infants to…”
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Meningococcal meningitis presenting postinfant group B meningococcal immunisation
Published in Archives of disease in childhood (01-09-2019)“…Correspondence to Prof Matthew D Snape, Department of Paediatrics, University of Oxford, Oxford OX3 7LJ, UK; matthew.snape@paediatrics.ox.ac.uk We report an…”
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Persistent Circulation of Vaccine Serotypes and Serotype Replacement After 5 Years of Infant Immunization With 13-Valent Pneumococcal Conjugate Vaccine in the United Kingdom
Published in The Journal of infectious diseases (28-03-2020)“…Abstract Background Following programmatic introduction of the 13-valent pneumococcal conjugate vaccine (PCV13), there is residual carriage and disease due to…”
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Safety and Immunogenicity of Novel Adenovirus Type 26– and Modified Vaccinia Ankara–Vectored Ebola Vaccines: A Randomized Clinical Trial
Published in JAMA : the journal of the American Medical Association (19-04-2016)“…IMPORTANCE: Developing effective vaccines against Ebola virus is a global priority. OBJECTIVE: To evaluate an adenovirus type 26 vector vaccine encoding Ebola…”
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Pandemic influenza A H1N1 vaccines and narcolepsy: vaccine safety surveillance in action
Published in The Lancet infectious diseases (01-03-2014)“…Summary The 2009 influenza A H1N1 pandemic placed unprecedented demand on public health authorities and the vaccine industry. Efforts were coordinated…”
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Respiratory syncytial virus seasonality and its implications on prevention strategies
Published in Human vaccines & immunotherapeutics (02-01-2018)“…With maternal and infant vaccines against respiratory syncytial virus (RSV) in development, it is timely to consider how the deployment of these vaccines might…”
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First-in-Human Randomized Study to Assess the Safety and Immunogenicity of an Investigational Respiratory Syncytial Virus (RSV) Vaccine Based on Chimpanzee-Adenovirus-155 Viral Vector-Expressing RSV Fusion, Nucleocapsid, and Antitermination Viral Proteins in Healthy Adults
Published in Clinical infectious diseases (06-05-2020)“…Respiratory syncytial virus (RSV) disease is a major cause of infant morbidity and mortality. This Phase I, randomized, observer-blind, placebo- and…”
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Elevations in blood glucose before and after the appearance of islet autoantibodies in children
Published in The Journal of clinical investigation (17-10-2022)“…The etiology of type 1 diabetes has polygenic and environmental determinants that lead to autoimmune responses against pancreatic β cells and promote β cell…”
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The price of prevention: what now for immunisation against meningococcus B?
Published in The Lancet (British edition) (03-08-2013)“…[...]the JCVI acknowledges that the relative rarity of meningococcal disease had precluded any realistic possibility of a classic efficacy trial.2 This is why…”
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Safety and Immunogenicity of an mRNA-Based hMPV/PIV3 Combination Vaccine in Seropositive Children
Published in Pediatrics (Evanston) (01-06-2024)“…Human metapneumovirus (hMPV) and parainfluenza virus type 3 (PIV3) are common respiratory illnesses in children. The safety and immunogenicity of an…”
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