Search Results - "Snape, Jason R"
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Pharmacology beyond the patient – The environmental risks of human drugs
Published in Environment international (01-08-2019)“…The presence of pharmaceuticals in the environment is a growing global concern and although environmental risk assessment is required for approval of new drugs…”
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Impact of Redox Conditions on Antibiotic Resistance Conjugative Gene Transfer Frequency and Plasmid Fate in Wastewater Ecosystems
Published in Environmental science & technology (01-12-2020)“…Wastewater is a common pathway for the spread of antibiotic resistance (AR) genes and bacteria into the environment. Biological treatment can mitigate this…”
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Management options for reducing the release of antibiotics and antibiotic resistance genes to the environment
Published in Environmental health perspectives (01-08-2013)“…There is growing concern worldwide about the role of polluted soil and water environments in the development and dissemination of antibiotic resistance. Our…”
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Ecotoxicological assessment of antibiotics: A call for improved consideration of microorganisms
Published in Environment international (01-12-2015)“…Antibiotics play a pivotal role in the management of infectious disease in humans, companion animals, livestock, and aquaculture operations at a global scale…”
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High Throughput Biodegradation-Screening Test To Prioritize and Evaluate Chemical Biodegradability
Published in Environmental science & technology (20-06-2017)“…Comprehensive assessment of environmental biodegradability of pollutants is limited by the use of low throughput systems. These are epitomized by the…”
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Environmentally Relevant Inoculum Concentrations Improve the Reliability of Persistent Assessments in Biodegradation Screening Tests
Published in Environmental science & technology (07-03-2017)“…Standard OECD biodegradation screening tests (BSTs) have not evolved at the same rate as regulatory concerns, which now place an increased emphasis on…”
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Increased cell numbers improve marine biodegradation tests for persistence assessment
Published in The Science of the total environment (01-03-2020)“…Currently available OECD biodegradation screening tests (BSTs) are not particularly suited for persistence screening. Their duration can be much less than…”
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ECOdrug: a database connecting drugs and conservation of their targets across species
Published in Nucleic acids research (04-01-2018)“…Abstract Pharmaceuticals are designed to interact with specific molecular targets in humans and these targets generally have orthologs in other species. This…”
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Implementing Ecopharmacovigilance in Practice: Challenges and Potential Opportunities
Published in Drug safety (01-07-2013)“…Ecopharmacovigilance (EPV) is a developing science and it is currently very unclear what it might mean in practice. We have performed a comparison between…”
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Machine Learning for Environmental Toxicology: A Call for Integration and Innovation
Published in Environmental science & technology (20-11-2018)“…Miller et al call for the integration and innovation of machine learning (ML) for environmental toxicology. There is a critical lack of literature concerning…”
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Simultaneous Fluorescent Gram Staining and Activity Assessment of Activated Sludge Bacteria
Published in Applied and Environmental Microbiology (01-10-2002)“…Classifications Services AEM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Improving the biodegradability in seawater test (OECD 306)
Published in The Science of the total environment (20-05-2019)“…Growth and extensive urbanisation of the human population has been accompanied by increased manufacture and use of chemical compounds. To classify the fate and…”
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Improving the ecological relevance of aquatic bacterial communities in biodegradability screening assessments
Published in The Science of the total environment (15-06-2018)“…Concentrating cells from aqueous samples is a common requirement for the enumeration of biomass, investigations of microbial diversity and detection of…”
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Co-optimization of sponge-core bioreactors for removing total nitrogen and antibiotic resistance genes from domestic wastewater
Published in The Science of the total environment (01-09-2018)“…Inadequate sanitation can lead to the spread of infectious diseases and antimicrobial resistance (AMR) via contaminated water. Unfortunately, wastewater…”
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Multi-laboratory Validation of a New Marine Biodegradation Screening Test for Chemical Persistence Assessment
Published in Environmental science & technology (07-04-2020)“…Current biodegradation screening tests are not specifically designed for persistence assessment of chemicals, often show high inter- and intra-test…”
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Fluoxetine Exhibits Pharmacological Effects and Trait-Based Sensitivity in a Marine Worm
Published in Environmental science & technology (02-08-2016)“…Global production of pharmacologically active compounds exceeds 100 000 tons annually, a proportion of which enters aquatic environments through patient use,…”
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Standard inocula preparations reduce the bacterial diversity and reliability of regulatory biodegradation tests
Published in Environmental science and pollution research international (2014)“…OECD ready biodegradability tests have been central to understanding the biodegradation of chemicals from a regulatory perspective for many decades. They are…”
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Integrating Omic Technologies into Aquatic Ecological Risk Assessment and Environmental Monitoring: Hurdles, Achievements, and Future Outlook
Published in Environmental health perspectives (01-01-2010)“…Background: In this commentary we present the findings from an international consortium on fish toxicogenomics sponsored by the U.K. Natural Environment…”
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Human Health Risk Assessment (HHRA) for environmental development and transfer of antibiotic resistance
Published in Environmental health perspectives (01-09-2013)“…Only recently has the environment been clearly implicated in the risk of antibiotic resistance to clinical outcome, but to date there have been few documented…”
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Environmental Persistence of Organic Pollutants: Guidance for Development and Review of POP Risk Profiles
Published in Integrated environmental assessment and management (01-10-2009)“…This article represents 1 of 9 articles generated from a Society of Environmental Toxicology and Chemistry (SETAC) Pellston Workshop entitled Science-Based…”
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