Search Results - "Smyth, G D"

60 YEARS OF POMC: Lipotropin and beta-endorphin: a perspective by Smyth, D G

“…Many important fields of research had a humble origin. In the distant past, A J P Martin’s discovery that amino acids could be separated by paper…”
Get full text

Mechanism of C-terminal amide formation by pituitary enzymes by Bradbury, A. F, Finnie, M. D. A, Smyth, D. G

Get full text

A novel peptide, pyroglutamylglutamylproline amide, in the rabbit prostate complex, structurally related to thyrotrophin-releasing hormone by Cockle, S M, Aitken, A, Beg, F, Smyth, D G

“…A novel peptide which cross-reacts with an antibody to thyrotrophin-releasing hormone has been isolated and characterized from the rabbit prostate complex. The…”
Get full text

β -Endorphin is processed differently in specific regions of rat pituitary and brain by Zakarian, S, Smyth, D. G

Get full text

The processing of beta-endorphin and alpha-melanotrophin in the pars intermedia of Xenopus laevis is influenced by background adaptation by Maruthainar, K, Peng-Loh, Y, Smyth, D G

“…beta-Endorphin- and alpha-melanotrophin (alpha-MSH)-related peptides were extracted from the pars intermedia of Xenopus laevis maintained for 2, 4 or 6 weeks…”
Get more information

Isolation and identification of two neutral thyrotropin releasing hormone-like peptides, pyroglutamylphenylalanineproline amide and pyroglutamylglutamineproline amide, from human seminal fluid by KHAN, Z, AITKEN, A, DEL RIO GARCIA, J, SMYTH, D. G

“…Two tripeptide amides with stuctures similar to thyrotropin releasing hormone were isolated from human seminal fluid and their amino acid sequences determined…”
Get full text

The thyrotropin-releasing hormone-like peptides pGlu-Phe-Pro amide and pGlu-Glu-Pro amide increase plasma triiodothyronine levels in the mouse; the activity is sensitive to testosterone by Cremades, Asunción, Peñafiel, Rafael, Rausell, Victor, Del Rio-Garcia, Jesus, Smyth, Derek G.

“…Three naturally occurring peptides, pGlu-Glu-Pro amide, pGlu-Phe-Pro amide and pGlu-Gln-Pro amide, with similar structures to thyrotropin releasing hormone…”
Get full text

Selective processing of beta-endorphin in regions of porcine pituitary by Smyth, D.G, Zakarian, S

“…The prohormone of beta-endorphin is unusual in that it is the precursor of more than one biologically active peptide (Fig. 1). The activation of this…”
Get full text

Endopeptidases and prohormone processing by Darby, N J, Smyth, D G

“…Peptide hormones and peptide transmitters are generated from polypeptide precursors by specific cleavage reactions which take place principally at sites formed…”
Get more information

The thyrotrophin-releasing hormone (TRH)-like peptides in rat prostate are not formed by expression of the TRH gene but are suppressed by thyroid hormone by Bilek, R, Gkonos, P J, Tavianini, M A, Smyth, D G, Roos, B A

“…Thyrotrophin-releasing hormone (TRH)-immunoreactive peptides were extracted from rat prostate and divided into two groups by mini-column cation exchange…”
Get more information

Endorphins are stored in biologically active and inactive forms: isolation of α-N -acetyl peptides by SMYTH, D. G, MASSEY, D. E, ZAKARIAN, S, FINNIE, M. D. A

Get full text

Distribution of beta-endorphin-related peptides in rat pituitary and brain by Zakarian, S, Smyth, D G

“…beta-Endorphin, the most potent known naturally occurring analgesic agent, is found in pituitary and brain in company with a series of structurally and…”
Get full text

Catalysis of slow C-terminal processing reactions by carboxypeptidase H by Smyth, D G, Maruthainar, K, Darby, N J, Fricker, L D

“…A hypothesis was examined that carboxypeptidase H (CpAse H), which is known to catalyse the release of lysine and arginine from the C-terminus of peptides, can…”
Get more information

Biosynthesis of the C-terminal amide in peptide hormones by Bradbury, A F, Smyth, D G

“…Recent developments in the study of peptide amidation are reviewed. The main areas covered are assay procedures, purification of amidating enzymes, co-factors…”
Get more information

beta-Endorphin and related peptides in pituitary, brain, pancreas and antrum by Smyth, D G

Get more information

Comparison of methods of evaluating hearing benefit of middle ear surgery by Toner, J G, Smyth, G D

“…The objective of this paper is to compare two methods of predicting the level of subjective patient benefit following reconstructive middle ear surgery. This…”
Get more information

C fragment of lipotropin has a high affinity for brain opiate receptors by BRADBURY, A. F, SMYTH, D. G, SNELL, C. R, BIRDSALL, N. J. M, HULME, E. C

Get full text

β-Endorphin and ACTH related peptides in primary cultures of rat anterior pituitary cells: evidence for different intracellular pools by Ham, J., Smyth, D.G.

“…Acid extracts of rat anterior pituitary cells and cell-derived culture media were shown to contain three forms of β-endorphin immunoreactive peptides,…”
Get full text

Thyrotrophin-releasing hormone-related polypeptides in rabbit prostate and semen are different from those in rabbit hypothalamus by Cockle, S M, Morrell, J M, Smyth, D G

“…TRH-related peptides were extracted from the hypothalamus and prostate gland of the rabbit. The peptides were fractionated by gel exclusion chromatography and…”
Get more information

Continuous infusion of propofol in dystrophia myotonica by WHITE, D. A, SMYTH, D. G

“…The use of intravenous infusions of propofol and atracurium in a 41-year-old woman, weighing 64 kg, with dystrophia myotonica during major oral surgery is…”
Get full text