Search Results - "Smyth, D. J."

Analysis of 17 autoimmune disease-associated variants in type 1 diabetes identifies 6q23/TNFAIP3 as a susceptibility locus by Fung, E Y M G, Smyth, D J, Howson, J M M, Cooper, J D, Walker, N M, Stevens, H, Wicker, L S, Todd, J A

“…As a result of genome-wide association studies in larger sample sets, there has been an increase in identifying genes that influence susceptibility to…”
Get full text

Genetic association of zinc transporter 8 (ZnT8) autoantibodies in type 1 diabetes cases by Howson, J. M. M., Krause, S., Stevens, H., Smyth, D. J., Wenzlau, J. M., Bonifacio, E., Hutton, J., Ziegler, A. G., Todd, J. A., Achenbach, P.

“…Aims/hypothesis Autoantibodies to zinc transporter 8 (ZnT8A) are associated with risk of type 1 diabetes. Apart from the SLC30A8 gene itself, little is known…”
Get full text

Multi‐parametric flow cytometric and genetic investigation of the peripheral B cell compartment in human type 1 diabetes by Thompson, W. S., Pekalski, M. L., Simons, H. Z., Smyth, D. J., Castro‐Dopico, X., Guo, H., Guy, C., Dunger, D. B., Arif, S., Peakman, M., Wallace, C., Wicker, L. S., Todd, J. A, Ferreira, R. C.

“…Summary The appearance of circulating islet‐specific autoantibodies before disease diagnosis is a hallmark of human type 1 diabetes (T1D), and suggests a role…”
Get full text

Cyanoacrylate tissue adhesives ― effective securement technique for intravascular catheters: in vitro testing of safety and feasibility by SIMONOVA, G, RICKARD, C. M, DUNSTER, K. R, SMYTH, D. J, MCMILLAN, D, FRASER, J. F

“…Partial or complete dislodgement of intravascular catheters remains a significant problem in hospitals despite current securement methods. Cyanoacrylate tissue…”
Get full text

No association of multiple type 2 diabetes loci with type 1 diabetes by Raj, S. M, Howson, J. M. M, Walker, N. M, Cooper, J. D, Smyth, D. J, Field, S. F, Stevens, H. E, Todd, J. A

“…Aims/hypothesis We used recently confirmed type 2 diabetes gene regions to investigate the genetic relationship between type 1 and type 2 diabetes, in an…”
Get full text

Comparing Check-All and Forced-Choice Question Formats in Web Surveys by Smyth, Jolene D., Dillman, Don A., Christian, Leah Melani, Stern, Michael J.

“…For survey researchers, it is common practice to use the check-all question format in Web and mail surveys but to convert to the forced-choice question format…”
Get full text

Analysis of the type 2 diabetes gene, TCF7L2, in 13,795 type 1 diabetes cases and control subjects by FIELD, S. F, HOWSON, J. M. M, SMYTH, D. J, WALKER, N. M, DUNGER, D. B, TODD, J. A

Get full text

Analysis of 19 genes for association with type I diabetes in the Type I Diabetes Genetics Consortium families by Howson, J M M, Walker, N M, Smyth, D J, Todd, J A

“…In recent years the pace of discovery of genetic associations with type I diabetes (T1D) has accelerated, with the total number of confirmed loci, including…”
Get full text

Follow-up of 1715 SNPs from the Wellcome Trust Case Control Consortium genome-wide association study in type I diabetes families by Cooper, J D, Walker, N M, Smyth, D J, Downes, K, Healy, B C, Todd, J A

“…The advent of genome-wide association (GWA) studies has revolutionized the detection of disease loci and provided abundant evidence for previously undetected…”
Get full text

Helminths in the hygiene hypothesis: sooner or later? by Maizels, R. M., McSorley, H. J., Smyth, D. J.

“…Summary There is increasing recognition that exposures to infectious agents evoke fundamental effects on the development and behaviour of the immune system…”
Get full text

Selectable marker-free transgenic barley producing a high level of cellulase (1,4-β-glucanase) in developing grains by XUE, G. P, PATEL, M, JOHNSON, J. S, SMYTH, D. J, VICKERS, C. E

“…The use of barley grains as bioreactors for high-level production of cellulase (1,4-beta-glucanase) was investigated. A hybrid cellulase gene, cel-hyb1, driven…”
Get full text

Analysis of 55 autoimmune disease and type II diabetes loci: further confirmation of chromosomes 4q27, 12q13.2 and 12q24.13 as type I diabetes loci, and support for a new locus, 12q13.3-q14.1 by Cooper, J D, Walker, N M, Healy, B C, Smyth, D J, Downes, K, Todd, J A

“…A candidate gene study was conducted on 10 established type II diabetes genes and 45 genes associated with autoimmune diseases, including type I diabetes…”
Get full text

Cloning and characterization of an orphan seven transmembrane receptor from Schistosoma mansoni by Pearson, M S, McManus, D P, Smyth, D J, Jones, M K, Sykes, A M, Loukas, A

“…A partial cDNA sequence was obtained from the human blood fluke, Schistosoma mansoni using a signal sequence trap approach. The full-length cDNA was cloned and…”
Get more information

Are OECD forecasts rational and useful?: a directional analysis by Ash, J.C.K., Smyth, D.J., Heravi, S.M.

“…Tests of direction are employed to evaluate the rationality and usefulness of a large data set of semi-annual forecasts for the G7 economies made by the OECD…”
Get full text

Presidential popularity: what matters most, macroeconomics or scandals? by Smyth, D. J., Taylor, S. W.

“…What accounts for the widely divergent impact of political scandal on the Nixon and Clinton administrations? This article argues that the extent to which an…”
Get full text

Testing the possible negative association of type 1 diabetes and atopic disease by analysis of the interleukin 4 receptor gene by MAIER, L. M, TWELLS, R. C. J, WALKER, N. M, BURREN, O. S, NUTLAND, S, RANCE, H, TUOMILEHTO-WOLF, E, TUOMILEHTO, J, GUJA, C, IONESCU-TIRGOVISTE, C, UNDLIEN, D. E, RØNNINGEN, K. S, HOWSON, J. M. M, CUCCA, F, TODD, J. A, LAM, A. C, CLAYTON, D. G, SMYTH, D. J, SAVAGE, D, CARSON, D, PATTERSON, C. C, SMINK, L. J

“…Variations in the interleukin 4 receptor A (IL4RA) gene have been reported to be associated with atopy, asthma, and allergy, which may occur less frequently in…”
Get full text

The accuracy of OECD forecasts of the international economy: balance of payments by Ash, J.C.K., Smyth, D.J., Heravi, S.M.

“…This paper examines the accuracy of forecasts of the international economy made by the OECD. Our large data set, comprising some 5500 pairs of forecasts and…”
Get full text

Comment to: Biason-Lauber A, Boehm B, Lang-Muritano M et al. (2005) association of childhood type 1 diabetes mellitus with a variant of PAX4: possible link to beta cell regenerative capacity. Diabetologia 48:900-905 by Maier, L M, Cooper, J D, Walker, N, Smyth, D J, Todd, J A

Get full text

Temperature-regulated expression of the tac/lacI system for overproduction of a fungal xylanase in Escherichia coli by Xue, G.P, Johnson, J.S, Smyth, D.J, Dierens, L.M, Wang, X, Simpson, G.D, Gobius, K.S, Aylward, J.H

“…Temperature-regulated expression of recombinant proteins in the tac promoter (Ptac) system was investigated. Expression levels of fungal xylanase and cellulase…”
Get full text

SURVEY EVIDENCE ON EXCESSIVE PUBLIC PESSIMISM ABOUT THE FUTURE BEHAVIOR OF UNEMPLOYMENT by DUA, PAMI, SMYTH, DAVID J.

“…Two of the questions in the Surveys of Consumer Attitudes undertaken by the Survey Research Center of the University of Michigan deal with households'…”
Get full text