Search Results - "Smyczynska, Urszula"

NormiRazor: tool applying GPU-accelerated computing for determination of internal references in microRNA transcription studies by Grabia, Szymon, Smyczynska, Urszula, Pagacz, Konrad, Fendler, Wojciech

“…Multi-gene expression assays are an attractive tool in revealing complex regulatory mechanisms in living organisms. Normalization is an indispensable step of…”
Get full text

A systemic approach to screening high-throughput RT-qPCR data for a suitable set of reference circulating miRNAs by Pagacz, Konrad, Kucharski, Przemyslaw, Smyczynska, Urszula, Grabia, Szymon, Chowdhury, Dipanjan, Fendler, Wojciech

“…The consensus on how to choose a reference gene for serum or plasma miRNA expression qPCR studies has not been reached and none of the potential candidates…”
Get full text

Impact of processing method on donated human breast milk microRNA content by Smyczynska, Urszula, Bartlomiejczyk, Marcin A, Stanczak, Marcin M, Sztromwasser, Pawel, Wesolowska, Aleksandra, Barbarska, Olga, Pawlikowska, Emilia, Fendler, Wojciech

“…Pasteurization of donated human milk preserves it for storage and makes it safe for feeding, but at the expense of its composition, nutritional values and…”
Get full text

MicroRNA Expression Profile in TSC Cell Lines and the Impact of mTOR Inhibitor by Pawlik, Bartłomiej, Grabia, Szymon, Smyczyńska, Urszula, Fendler, Wojciech, Dróżdż, Izabela, Liszewska, Ewa, Jaworski, Jacek, Kotulska, Katarzyna, Jóźwiak, Sergiusz, Młynarski, Wojciech, Trelińska, Joanna

“…The aim of this study was to assess the potential implication of microRNA on tuberous sclerosis (TSC) pathogenesis by performing microRNA profiling on cell…”
Get full text

Identification of BRCA1/2 mutation female carriers using circulating microRNA profiles by Elias, Kevin, Smyczynska, Urszula, Stawiski, Konrad, Nowicka, Zuzanna, Webber, James, Kaplan, Jakub, Landen, Charles, Lubinski, Jan, Mukhopadhyay, Asima, Chakraborty, Dona, Connolly, Denise C., Symecko, Heather, Domchek, Susan M., Garber, Judy E., Konstantinopoulos, Panagiotis, Fendler, Wojciech, Chowdhury, Dipanjan

“…Identifying germline BRCA1/2 mutation carriers is vital for reducing their risk of breast and ovarian cancer. To derive a serum miRNA-based diagnostic test we…”
Get full text

Association of circulating miRNAS in patients with Alstrőm and Bardet-Biedl syndromes with clinical course parameters by Zmyslowska, Agnieszka, Smyczynska, Urszula, Stanczak, Marcin, Jeziorny, Krzysztof, Szadkowska, Agnieszka, Fendler, Wojciech, Borowiec, Maciej

“…Patients with the rare syndromic forms of monogenic diabetes: Alström syndrome (ALMS) and Bardet-Biedl syndrome (BBS) have multiple metabolic abnormalities,…”
Get full text

Cancer Stem Cell Markers in Rhabdomyosarcoma in Children by Radzikowska, Joanna, Czarnecka, Anna M, Klepacka, Teresa, Rychłowska-Pruszyńska, Magdalena, Raciborska, Anna, Dembowska-Bagińska, Bożenna, Pronicki, Maciej, Kukwa, Andrzej, Fendler, Wojciech, Smyczyńska, Urszula, Kukwa, Wojciech, Krzeski, Antoni

“…(1) Background: The aim of the present study was to assess the cancer stem cell (CSC) markers CD24, CD44, CD133, and ALDH1A1 in rhabdomyosarcoma (RMS) in…”
Get full text

Significance of Direct Confirmation of Growth Hormone Insensitivity for the Diagnosis of Primary IGF-I Deficiency by Smyczyńska, Joanna, Smyczyńska, Urszula, Hilczer, Maciej, Stawerska, Renata, Lewiński, Andrzej

“…Primary insulin-like growth factor-I (IGF-I) deficiency is a synonym of growth hormone (GH) insensitivity (GHI), however the necessity of direct confirmation…”
Get full text

Biological basis of extensive pleiotropy between blood traits and cancer risk by Pardo-Cea, Miguel Angel, Farré, Xavier, Esteve, Anna, Palade, Joanna, Espín, Roderic, Mateo, Francesca, Alsop, Eric, Alorda, Marc, Blay, Natalia, Baiges, Alexandra, Shabbir, Arzoo, Comellas, Francesc, Gómez, Antonio, Arnan, Montserrat, Teulé, Alex, Salinas, Monica, Berrocal, Laura, Brunet, Joan, Rofes, Paula, Lázaro, Conxi, Conesa, Miquel, Rojas, Juan Jose, Velten, Lars, Fendler, Wojciech, Smyczynska, Urszula, Chowdhury, Dipanjan, Zeng, Yong, He, Housheng Hansen, Li, Rong, Van Keuren-Jensen, Kendall, de Cid, Rafael, Pujana, Miquel Angel

“…The immune system has a central role in preventing carcinogenesis. Alteration of systemic immune cell levels may increase cancer risk. However, the extent to…”
Get full text

Proteomic and Transcriptomic Landscapes of Alström and Bardet-Biedl Syndromes by Smyczynska, Urszula, Stanczak, Marcin, Kuljanin, Miljan, Włodarczyk, Aneta, Stoczynska-Fidelus, Ewelina, Taha, Joanna, Pawlik, Bartłomiej, Borowiec, Maciej, Mancias, Joseph D, Mlynarski, Wojciech, Rieske, Piotr, Fendler, Wojciech, Zmysłowska, Agnieszka

“…Alström syndrome (ALMS) and Bardet-Biedl syndrome (BBS) are rare genetic diseases with a number of common clinical features ranging from early-childhood…”
Get full text

Neural network models - a novel tool for predicting the efficacy of growth hormone (GH) therapy in children with short stature by Smyczynska, Joanna, Hilczer, Maciej, Smyczynska, Urszula, Stawerska, Renata, Tadeusiewicz, Ryszard, Lewinski, Andrzej

“…The leading method for prediction of growth hormone (GH) therapy effectiveness are multiple linear regression (MLR) models. Best of our knowledge, we are the…”
Get more information

Transient Isolated, Idiopathic Growth Hormone Deficiency-A Self-Limiting Pediatric Disease with Male Predominance or a Diagnosis Based on Uncertain Criteria? Lesson from 20 Years' Real-World Experience with Retesting at One Center by Smyczyńska, Joanna, Hilczer, Maciej, Smyczyńska, Urszula, Lewiński, Andrzej, Stawerska, Renata

“…In the majority of children with growth hormone (GH) deficiency (GHD), normal GH secretion may occur before the attainment of final height. The aim of the…”
Get full text

The Therapeutic Effect of Nordic Walking on Freezing of Gait in Parkinson’s Disease: A Pilot Study by Bogucki, Andrzej, Smyczyńska, Urszula, Gajos, Agata, Wróblewska, Agata

“…Introduction. The effectiveness of the currently utilized therapies for FoG is limited. Several studies demonstrated a beneficial impact of Nordic walking (NW)…”
Get full text

Obesity-Related Complications Including Dysglycemia Based on 1-h Post-Load Plasma Glucose in Children and Adolescents Screened before and after COVID-19 Pandemic by Smyczyńska, Joanna, Olejniczak, Aleksandra, Różycka, Paulina, Chylińska-Frątczak, Aneta, Michalak, Arkadiusz, Smyczyńska, Urszula, Mianowska, Beata, Pietrzak, Iwona, Szadkowska, Agnieszka

“…Childhood obesity, with its metabolic complications, is a problem of public health. The International Diabetes Federation (IDF) has recommended glucose levels…”
Get full text

mTOR Inhibitor Treatment in Patients with Tuberous Sclerosis Complex Is Associated with Specific Changes in microRNA Serum Profile by Pawlik, Bartłomiej, Smyczyńska, Urszula, Grabia, Szymon, Fendler, Wojciech, Dróżdż, Izabela, Bąbol-Pokora, Katarzyna, Kotulska, Katarzyna, Jóźwiak, Sergiusz, Borkowska, Julita, Młynarski, Wojciech, Trelińska, Joanna

“…The aim of this study was to determine the serum profiles of miRNAs in patients with tuberous sclerosis (TSC) upon sirolimus treatment and compare them with…”
Get full text

TP53-Deficient Angiosarcoma Expression Profiling in Rat Model by Smyczyńska, Urszula, Strzemecki, Damian, Czarnecka, Anna M., Fendler, Wojciech, Fiedorowicz, Michał, Wełniak-Kamińska, Marlena, Guzowska, Magdalena, Synoradzki, Kamil, Cheda, Łukasz, Rogulski, Zbigniew, Grieb, Paweł

“…Sarcomas are a heterogeneous group of malignant tumors, that develop from mesenchymal cells. Sarcomas are tumors associated with poor prognosis and expected…”
Get full text

Seasonality of vitamin D concentrations and the incidence of vitamin D deficiency in children and adolescents from central Poland by Smyczyńska, Joanna, Smyczyńska, Urszula, Stawerska, Renata, Domagalska-Nalewajek, Hanna, Lewiński, Andrzej, Hilczer, Maciej

Get full text

Pre-treatment growth and IGF-I deficiency as main predictors of response to growth hormone therapy in neural models by Smyczyńska, Urszula, Smyczyńska, Joanna, Hilczer, Maciej, Stawerska, Renata, Tadeusiewicz, Ryszard, Lewiński, Andrzej

“…Mathematical models have been applied in prediction of growth hormone treatment effectiveness in children since the end of 1990s. Usually they were multiple…”
Get full text

DNA Polymerase Theta Plays a Critical Role in Pancreatic Cancer Development and Metastasis by Smolinska, Agnieszka, Singer, Kerstin, Golchert, Janine, Smyczynska, Urszula, Fendler, Wojciech, Sendler, Matthias, van den Brandt, Jens, Singer, Stephan, Homuth, Georg, Lerch, Markus M, Moskwa, Patryk

“…Pancreatic ductal adenocarcinoma (PDAC), due to its genomic heterogeneity and lack of effective treatment, despite decades of intensive research, will become…”
Get full text

Prediction of Radiation-Induced Hypothyroidism Using Radiomic Data Analysis Does Not Show Superiority over Standard Normal Tissue Complication Models by Smyczynska, Urszula, Grabia, Szymon, Nowicka, Zuzanna, Papis-Ubych, Anna, Bibik, Robert, Latusek, Tomasz, Rutkowski, Tomasz, Fijuth, Jacek, Fendler, Wojciech, Tomasik, Bartlomiej

“…State-of-art normal tissue complication probability (NTCP) models do not take into account more complex individual anatomical variations, which can be…”
Get full text