Search Results - "Smulders, K"

Objective gait assessment in individuals with knee osteoarthritis using inertial sensors: A systematic review and meta-analysis by Boekesteijn, R J, van Gerven, J, Geurts, A C H, Smulders, K

“…Objective assessment of gait using inertial sensors has shown promising results for functional evaluations in individuals with knee osteoarthritis (OA)…”
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Mitochondrial electron transport chain defects modify Parkinson's disease phenotypes in a Drosophila model by O'Hanlon, Maria E., Tweedy, Clare, Scialo, Filippo, Bass, Rosemary, Sanz, Alberto, Smulders-Srinivasan, Tora K.

“…INTRODUCTIONMitochondrial defects have been implicated in Parkinson's disease (PD) since complex I poisons were found to cause accelerated parkinsonism in…”
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Are postural responses to backward and forward perturbations processed by different neural circuits? by Nonnekes, J, Scotti, A, Oude Nijhuis, L.B, Smulders, K, Queralt, A, Geurts, A.C.H, Bloem, B.R, Weerdesteyn, V

“…Highlights • Balance was perturbed in 11 healthy subjects in forward and backward directions. • Twenty-five percent of trials were combined with a startling…”
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Individuals with knee osteoarthritis show few limitations in balance recovery responses after moderate gait perturbations by Boekesteijn, R.J., Keijsers, N.L.W., Defoort, K., Geurts, A.C.H., Smulders, K.

“…Knee osteoarthritis causes structural joint damage. The resultant symptoms can impair the ability to recover from unexpected gait perturbations. This study…”
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Do cognitive measures and brain circuitry predict outcomes of exercise in Parkinson Disease: a randomized clinical trial by King, L A, Peterson, D S, Mancini, M, Carlson-Kuhta, P, Fling, B W, Smulders, K, Nutt, J G, Dale, M, Carter, J, Winters-Stone, K M, Horak, F B

“…There is emerging research detailing the relationship between balance/gait/falls and cognition. Imaging studies also suggest a link between structural and…”
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Frequent attendance of primary care out-of-hours services in The Netherlands: characteristics of patients and presented morbidity by den Boer-Wolters, Dianne, Knol, Mirjam J, Smulders, Kien, de Wit, Niek J

“…Background. Over the last years, a system of regional general practices was developed in The Netherlands, responsible for the primary care out-of-hours…”
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Transmitochondrial embryonic stem cells containing pathogenic mtDNA mutations are compromised in neuronal differentiation by Kirby, D. M. , Rennie, K. J. , Smulders-Srinivasan, T. K. , Acin-Perez, R. , Whittington, M. , Enriquez, J.-A. , Trevelyan, A. J. , Turnbull, D. M. , Lightowlers, R. N. 

“…Objectives:  Defects of the mitochondrial genome (mtDNA) cause a series of rare, mainly neurological disorders. In addition, they have been implicated in more…”
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Mechanism of neurodegeneration of neurons with mitochondrial DNA mutations by Abramov, Andrey Y., Smulders-Srinivasan, Tora K., Kirby, Denise M., Acin-Perez, Rebeca, Enriquez, José Antonio, Lightowlers, Robert N., Duchen, Michael R., Turnbull, Douglass M.

“…Mutations of mitochondrial DNA are associated with a wide spectrum of disorders, primarily affecting the central nervous system and muscle function. The…”
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152 DOES DUAL-TASK INTERFERENCE PREDICT FALLING IN PARKINSON'S DISEASE PATIENTS? by Smulders, K, Esselink, R.A.J, Kessels, R.P.C, Borm, G.F, Geurts, A.C.H, Bloem, B.R

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201 RATIONALE AND DESIGN OF THE PARKFIT STUDY: A RANDOMIZED CONTROLLED TRIAL TO INCREASE PHYSICAL ACTIVITY IN PATIENTS WITH PARKINSON'S DISEASE by Speelman, A, van Nimwegen, M, Smulders, K, Overeem, S, Borm, G, Backx, F, Bloem, B, Munneke, M

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Screens for piwi Suppressors in Drosophila Identify Dosage-Dependent Regulators of Germline Stem Cell Division by Smulders-Srinivasan, Tora K, Lin, Haifan

“…The Drosophila piwi gene is the founding member of the only known family of genes whose function in stem cell maintenance is highly conserved in both animal…”
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Debridement, antibiotics, and implant retention after revision arthroplasty: antibiotic mismatch, timing, and repeated DAIR associated with poor outcome by Veerman, Karin, Raessens, Joris, Telgt, Denise, Smulders, Katrijn, Goosen, Jon H M

“…AimsDebridement, antibiotics, and implant retention (DAIR) is a widely accepted form of surgical treatment for patients with an early periprosthetic joint…”
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Objective assesment of gait in end-stage hip and knee osteoarthritis using wearable sensors by Boekesteijn, R.J., Busch, V.J., Smolders, J.M., Geurts, A.C., Smulders, K.

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Patient-reported outcome measures, complication rates, and re-revision rates are not associated with the indication for revision total hip arthroplasty: a prospective evaluation of 647 consecutive patients by Innocenti, Matteo, Smulders, Katrijn, Willems, Jore H, Goosen, Jon H M, Gijs van Hellemondt

“…AimsThe aim of this study was to explore the relationship between reason for revision total hip arthroplasty (rTHA) and outcomes in terms of patient-reported…”
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Promotion of physical activity and fitness in sedentary patients with Parkinson’s disease: randomised controlled trial by van Nimwegen, Marlies, Speelman, Arlène D, Overeem, Sebastiaan, van de Warrenburg, Bart P, Smulders, Katrijn, Dontje, Manon L, Borm, George F, Backx, Frank J G, Bloem, Bastiaan R, Munneke, Marten

“…Objective To evaluate whether a multifaceted behavioural change programme increases physical activities in patients with Parkinson’s disease.Design Multicentre…”
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Stay short or go long in revision THA with Paprosky type II femoral defects: A comparative study with the use of an uncemented distal fixating modular stem and a primary monobloc conical stems with 5 years follow-up by Willems, J H, Smulders, K, Innocenti, M, Bosker, B H, van Hellemondt, G G

“…In the revisions for Paprosky type II femoral defects, diaphyseal fixating femoral stems are commonly used. To preserve bone stock, the use of a shorter…”
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Understanding the Multifaceted Role of Human Down Syndrome Kinase DYRK1A by Kay, L J, Smulders-Srinivasan, T K, Soundararajan, M

“…The dual-specificity tyrosine (Y) phosphorylation-regulated kinase DYRK1A, also known as Down syndrome (DS) kinase, is a dosage-dependent signaling kinase that…”
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Speeding Up Gait in Parkinson's Disease by Peterson, Daniel S, Mancini, Martina, Fino, Peter C, Horak, Fay, Smulders, Katrijn

“…Gait speed is an important outcome that relates to mobility, function, and mortality, and is altered in people with Parkinson's disease (PwPD). However,…”
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Reinfection and re-revision rates of 113 two-stage revisions in infected TKA by Bongers, Joris, Jacobs, Anouk M.E., Smulders, Katrijn, van, Gijs G., Goosen, Jon H.M.

“…Introduction: Two-stage revision is the most frequently performed revision procedure of a (suspected) periprosthetic joint infection (PJI) after total knee…”
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A Drosophila chromatin factor interacts with the Piwi-interacting RNA mechanism in niche cells to regulate germline stem cell self-renewal by Smulders-Srinivasan, Tora K, Szakmary, Akos, Lin, Haifan

“…Stem cell research has been focused on niche signaling and epigenetic programming of stem cells. However, epigenetic programming of niche cells remains…”
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