Search Results - "Smoyer, W E"

Challenges in Developing Evidence-Based Drug Dosing Guidelines for Adults and Children Receiving Renal Replacement Therapy by Mueller, BA, Smoyer, WE

“…The challenges of appropriate drug dosing in patients with renal failure requiring renal replacement therapy (RRT) have been exacerbated by recent trends in…”
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Regulation of podocyte structure during the development of nephrotic syndrome by SMOYER, W. E, MUNDEL, P

“…Nephrotic syndrome is a common kidney disease seen in both children and adults. The clinical syndrome includes massive proteinuria, hypoalbuminemia, edema, and…”
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Podocyte alpha-actinin induction precedes foot process effacement in experimental nephrotic syndrome by Smoyer, W E, Mundel, P, Gupta, A, Welsh, M J

“…Attachment of podocytes to the glomerular basement membrane is thought to be mediated primarily by alpha 3/beta 1-integrins and by cytoskeletal proteins…”
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Amino acid loss and nitrogen balance in critically ill children with acute renal failure: A prospective comparison between classic hemofiltration and hemofiltration with dialysis by Maxvold, Norma J, Smoyer, William E, Custer, Joseph R, Bunchman, Timothy E

“…HYPOTHESIS:Amino acid (AA) loss is not equivalent on continuous venovenous hemofiltration (CVVH) compared with continuous venovenous hemodiafiltration (CVVHD)…”
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Pioglitazone Enhances the Beneficial Effects of Glucocorticoids in Experimental Nephrotic Syndrome by Agrawal, S., Chanley, M. A., Westbrook, D., Nie, X., Kitao, T., Guess, A. J., Benndorf, R., Hidalgo, G., Smoyer, W. E.

“…Glucocorticoids are the primary therapy for nephrotic syndrome (NS), but have serious side effects and are ineffective in ~20–50% of patients…”
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Management of acute renal failure in the pediatric patient: hemofiltration versus hemodialysis by Maxvold, N J, Smoyer, W E, Gardner, J J, Bunchman, T E

“…Although outcome data for acute renal failure (ARF) in the adult population (analyzed by etiology of ARF, severity of illness, and modality of treatment) are…”
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Regulation of mouse podocyte process dynamics by protein tyrosine phosphatases : Rapid Communication by REISER, J, PIXLEY, F. J, HUG, A, KRIZ, W, SMOYER, W. E, STANLEY, E. R, MUNDEL, P

“…Effacement of podocyte foot processes occurs early in many glomerular diseases associated with proteinuria and is accompanied by a reorganization of the actin…”
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Treatment of hypertensive children with amlodipine by Flynn, Joseph T, Smoyer, William E, Bunchman, Timothy E

“…Amlodipine, a long-acting dihydropyridine calcium channel blocking agent, was administered to 55 children (age: 11.5 ± 5.4 years) with hypertension, 49 of whom…”
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Peritoneal dialysis for management of pediatric acute renal failure by Flynn, JT, Kershaw, DB, Smoyer, WE, Brophy, PD, McBryde, KD, Bunchman, TE

“…Division of Pediatric Nephrology, C.S. Mott Children's Hospital, University of Michigan, Ann Arbor, USA. jflynn@montefiore.org…”
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Childhood diethylene glycol poisoning treated with alcohol dehydrogenase inhibitor fomepizole and hemodialysis by Brophy, Patrick D., Tenenbein, Milton, Gardner, John, Bunchman, Timothy E., Smoyer, William E.

“…Diethylene glycol (DEG), a commonly used solvent, has been implicated in multiple poisoning deaths, the most recent being the Haitian acetaminophen tragedy…”
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Altered expression of glomerular heat shock protein 27 in experimental nephrotic syndrome by Smoyer, W E, Gupta, A, Mundel, P, Ballew, J D, Welsh, M J

“…Although nephrotic syndrome is a very common kidney disease, little is known about the molecular changes occurring within glomerular capillary loops during…”
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Outcome of antineutrophil cytoplasmic autoantibodies-positive glomerulonephritis and vasculitis in children: A single-center experience by Valentini, Rudolph P., Smoyer, William E., Sedman, Aileen B., Kershaw, David B., Gregory, Melissa J., Bunchman, Timothy E.

“…Vasculitis associated with antineutrophil cytoplasmic autoantibodies (ANCA) can be accompanied by a focal and necrotizing glomerulonephritis that carries a…”
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Oral feeding of renal tubular antigen abrogates interstitial nephritis and renal failure in Brown Norway rats by Pham, Kevin, Smoyer, William E., Archer, D. Clay, Gabbai, Francis, Kelly, Carolyn J.

“…Oral feeding of renal tubular antigen abrogates interstitial nephritis and renal failure in Brown Norway rats. We have examined whether oral feeding of antigen…”
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Improved growth in young children with severe chronic renal insufficiency who use specified nutritional therapy by PAREKH, Rulan S, FLYNN, Joseph T, SMOYER, William E, MILNE, Joan L, KERSHAW, David B, BUNCHMAN, Timothy E, SEDMAN, Aileen B

“…Growth in children with chronic renal failure caused by polyuric, salt-wasting diseases may be hampered if ongoing sodium and water losses are not corrected…”
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Intravenous nicardipine for treatment of severe hypertension in children by Flynn, Joseph T., Mottes, Theresa A., Brophy, Patrick D., Kershaw, David B., Smoyer, William E., Bunchman, Timothy E.

“…Objective: To examine the effect of intravenous nicardipine in the treatment of children with severe hypertension. Methods: The medical records of 29 children…”
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Quantitative morphometry of renal biopsies prior to cyclosporine in nephrotic syndrome by SMOYER, W. E, GREGORY, M. J, BAJWA, R. S, JOHNSON, K. J, BUNCHMAN, T. E

“…Use of cyclosporine (CsA) in the management of children with steroid-resistant (SRNS) and steroid-dependent (SDNS) nephrotic syndrome has become increasingly…”
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Heterogeneous T cell receptor Vβ gene repertoire in murine interstitial nephritis by Heeger, Peter S., Smoyer, William E., Jones, Monica, Hopfer, Suellen, Neilson, Eric G.

“…Heterogeneous T cell receptor Vβ gene repertoire in murine interstitial nephritis. Anti-tubular basement membrane disease (αTBM) produces T cell-mediated…”
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Urethral stones: US for identification in boys with hematuria and dysuria by Kessler, A, Rosenberg, H K, Smoyer, W E, Blyth, B

“…There are multiple causes for hematuria in infants and children. When hematuria is accompanied by dysuria, however, one should focus attention on the lower…”
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Ischemic acute renal failure induces differential expression of small heat shock proteins by SMOYER, W. E, RANSOM, R, HARRIS, R. C, WELSH, M. J, LUTSCH, G, BENNDORF, R

“…AlphaB-crystallin and heat shock protein (hsp) 25 are structurally and functionally related small stress proteins induced by a variety of insults, including…”
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Identification and Characterization of hic-5/ARA55 as an hsp27 Binding Protein by Jia, Yifeng, Ransom, Richard F., Shibanuma, Motoko, Liu, Chenghua, Welsh, Michael J., Smoyer, William E.

“…hsp27 has been reported to participate in a wide variety of activities, including resistance to thermal and metabolic stress, regulation of growth and…”
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