Search Results - "Smorodinsky, Nechama"

Requirement of ATM-Dependent Monoubiquitylation of Histone H2B for Timely Repair of DNA Double-Strand Breaks by Moyal, Lilach, Lerenthal, Yaniv, Gana-Weisz, Mali, Mass, Gilad, So, Sairei, Wang, Shih-Ya, Eppink, Berina, Chung, Young Min, Shalev, Gil, Shema, Efrat, Shkedy, Dganit, Smorodinsky, Nechama I., van Vliet, Nicole, Kuster, Bernhard, Mann, Matthias, Ciechanover, Aaron, Dahm-Daphi, Jochen, Kanaar, Roland, Hu, Mickey C.-T., Chen, David J., Oren, Moshe, Shiloh, Yosef

“…The cellular response to DNA double-strand breaks (DSBs) is mobilized by the protein kinase ATM, which phosphorylates key players in the DNA damage response…”
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Active immunization against vasoactive intestinal polypeptide decreases neuronal recruitment and inhibits reproduction in zebra finches by Vistoropsky, Yulia, Heiblum, Rachel, Smorodinsky, Nechama-Ina, Barnea, Anat

“…ABSTRACT Neurogenesis and neuronal recruitment occur in adult brains of many vertebrates, and the hypothesis is that these phenomena contribute to the brain…”
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Differential molecular regulation of processing and membrane expression of Type-I BMP receptors: implications for signaling by Hirschhorn, Tal, Levi-Hofman, Michal, Danziger, Oded, Smorodinsky, Nechama I., Ehrlich, Marcelo

“…The Type-I bone morphogenetic protein receptors (BMPRs), BMPR1A and BMPR1B, present the highest sequence homology among BMPRs, suggestive of functional…”
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Differential regulation of Smad3 and of the type II transforming growth factor-β receptor in mitosis: implications for signaling by Hirschhorn, Tal, Barizilay, Lior, Smorodinsky, Nechama I, Ehrlich, Marcelo

“…The response to transforming growth factor-β (TGF-β) depends on cellular context. This context is changed in mitosis through selective inhibition of vesicle…”
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Cell surface-associated anti-MUC1-derived signal peptide antibodies: implications for cancer diagnostics and therapy by Kovjazin, Riva, Horn, Galit, Smorodinsky, Nechama I, Shapira, Michael Y, Carmon, Lior

“…The MUC1 tumor associated antigen is highly expressed on a range of tumors. Its broad distribution on primary tumors and metastases renders it an attractive…”
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MUC1-ARF-A Novel MUC1 Protein That Resides in the Nucleus and Is Expressed by Alternate Reading Frame Translation of MUC1 mRNA by Chalick, Michael, Jacobi, Oded, Pichinuk, Edward, Garbar, Christian, Bensussan, Armand, Meeker, Alan, Ziv, Ravit, Zehavi, Tania, Smorodinsky, Nechama I, Hilkens, John, Hanisch, Franz-Georg, Rubinstein, Daniel B, Wreschner, Daniel H

“…Translation of mRNA in alternate reading frames (ARF) is a naturally occurring process heretofore underappreciated as a generator of protein diversity. The…”
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In vivo anti-MUC1+ tumor activity and sequences of high-affinity anti-MUC1-SEA antibodies by Pichinuk, Edward, Chalik, Michael, Benhar, Itai, Ginat-Koton, Ravit, Ziv, Ravit, Smorodinsky, Nechama I., Haran, Gabi, Garbar, Christian, Bensussan, Armand, Meeker, Alan, Guillaume, Thierry, Rubinstein, Daniel B., Wreschner, Daniel H.

“…Cleavage of the MUC1 glycoprotein yields two subunits, an extracellular alpha-subunit bound to a smaller transmembrane beta-subunit. Monoclonal antibodies…”
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Constitutive negative regulation in the processing of the anti-Müllerian hormone receptor II by Hirschhorn, Tal, di Clemente, Nathalie, Amsalem, Ayelet R, Pepinsky, R Blake, Picard, Jean-Yves, Smorodinsky, Nechama I, Cate, Richard L, Ehrlich, Marcelo

“…The levels and intracellular localization of wild-type transforming growth factor β superfamily (TGFβ-SF) receptors are tightly regulated by endocytic…”
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Dab2 inhibits the cholesterol-dependent activation of JNK by TGF-β by Shapira, Keren E, Hirschhorn, Tal, Barzilay, Lior, Smorodinsky, Nechama I, Henis, Yoav I, Ehrlich, Marcelo

“…Transforming growth factor-β (TGF-β) ligands activate Smad-mediated and noncanonical signaling pathways in a cell context-dependent manner. Localization of…”
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Quantitative single cell monitoring of protein synthesis at subcellular resolution using fluorescently labeled tRNA by Barhoom, Sima, Kaur, Jaskiran, Cooperman, Barry S., Smorodinsky, Nechama I., Smilansky, Zeev, Ehrlich, Marcelo, Elroy-Stein, Orna

“…We have developed a novel technique of using fluorescent tRNA for translation monitoring (FtTM). FtTM enables the identification and monitoring of active…”
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FIE, a nuclear PRC2 protein, forms cytoplasmic complexes in Arabidopsis thaliana by Oliva, Moran, Butenko, Yana, Hsieh, Tzung-Fu, Hakim, Ofir, Katz, Aviva, Smorodinsky, Nechama I., Michaeli, Daphna, Fischer, Robert L., Ohad, Nir

“…Polycomb group (PcG) proteins are evolutionarily conserved chromatin modifiers that regulate developmental pathways in plants. PcGs form nuclear multi-subunit…”
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The MUC1 SEA Module Is a Self-cleaving Domain by Levitin, Fiana, Stern, Omer, Weiss, Mordechai, Gil-Henn, Chava, Ziv, Ravit, Prokocimer, Zofnat, Smorodinsky, Nechama I., Rubinstein, Daniel B., Wreschner, Daniel H.

“…MUC1, a glycoprotein overexpressed by a variety of human adenocarcinomas, is a type I transmembrane protein (MUC1/TM) that soon after its synthesis undergoes…”
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Epizootic Hemorrhagic Disease Virus Induces and Benefits from Cell Stress, Autophagy, and Apoptosis by Shai, Ben, Schmukler, Eran, Yaniv, Roy, Ziv, Naomi, Horn, Galit, Bumbarov, Velizar, Yadin, Hagai, Smorodinsky, Nechama I, Bacharach, Eran, Pinkas-Kramarski, Ronit, Ehrlich, Marcelo

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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ImMucin: A novel therapeutic vaccine with promiscuous MHC binding for the treatment of MUC1-expressing tumors by Kovjazin, Riva, Volovitz, Ilan, Kundel, Yulia, Rosenbaum, Eli, Medalia, Gal, Horn, Galit, Smorodinsky, Nechama I, Brenner, Baruch, Carmon, Lior

“…Abstract An optimal cancer vaccine should be able to induce highly potent, long-lasting, tumor-specific responses in the majority of the cancer patient…”
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Negative Regulation of the Endocytic Adaptor Disabled-2 (Dab2) in Mitosis by Chetrit, David, Barzilay, Lior, Horn, Galit, Bielik, Tom, Smorodinsky, Nechama I., Ehrlich, Marcelo

“…Mitotic cells undergo extensive changes in shape and size through the altered regulation and function of their membrane trafficking machinery. Disabled 2…”
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Antibody Targeting of Cell-Bound MUC1 SEA Domain Kills Tumor Cells by PICHINUK, Edward, BENHAR, Itai, WRESCHNER, Daniel H, JACOBI, Oded, CHALIK, Michael, WEISS, Lotem, ZIV, Ravit, SYMPSON, Carolyn, KARWA, Amolkumar, SMORODINSKY, Nechama I, RUBINSTEIN, Daniel B

“…The cell-surface glycoprotein MUC1 is a particularly appealing target for antibody targeting, being selectively overexpressed in many types of cancers and a…”
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LY6S, a New IFN-Inducible Human Member of the Ly6a Subfamily Expressed by Spleen Cells and Associated with Inflammation and Viral Resistance by Shmerling, Moriya, Chalik, Michael, Smorodinsky, Nechama I, Meeker, Alan, Roy, Sujayita, Sagi-Assif, Orit, Meshel, Tsipi, Danilevsky, Artem, Shomron, Noam, Levinger, Shmuel, Nishry, Bar, Baruchi, David, Shargorodsky, Avital, Ziv, Ravit, Sarusi-Portuguez, Avital, Lahav, Maoz, Ehrlich, Marcelo, Braschi, Bryony, Bruford, Elspeth, Witz, Isaac P, Wreschner, Daniel H

“…Syntenic genomic loci on human chromosome 8 and mouse chromosome 15 (mChr15) code for LY6/Ly6 (lymphocyte Ag 6) family proteins. The 23 murine family genes…”
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ERK and PI3K regulate different aspects of the epithelial to mesenchymal transition of mammary tumor cells induced by truncated MUC1 by Horn, Galit, Gaziel, Avital, Wreschner, Daniel H., Smorodinsky, Nechama I., Ehrlich, Marcelo

“…Epithelial to mesenchymal transition (EMT) integrates changes to cell morphology and signaling pathways resulting from modifications to the cell's…”
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Characterization of Novel Multiantigenic Vaccine Candidates with Pan-HLA Coverage against Mycobacterium tuberculosis by Kovjazin, Riva, Shitrit, David, Preiss, Rachel, Haim, Ilanit, Triezer, Lev, Fuks, Leonardo, Nader, Abdel Rahman, Raz, Meir, Bardenstein, Ritta, Horn, Galit, Smorodinsky, Nechama I, Carmon, Lior

“…Classifications Services CVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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The MUC1 oncoprotein as a functional target: Immunotoxin binding to α/β junction mediates cell killing by Rubinstein, Daniel B., Karmely, Maya, Pichinuk, Edward, Ziv, Ravit, Benhar, Itai, Feng, Ningping, Smorodinsky, Nechama I., Wreschner, Daniel H.

“…MUC1, a heavily glycosylated mucin, has generated considerable interest as a target for tumor killing because of its overexpression in malignancies…”
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