Search Results - "Smolina, Irina V"

Ultrasensitive detection of DNA and protein markers in cancer cells by Smolina, Irina V, Broude, Natalia E

“…Cancer cells differ from normal cells in various parameters, and these differences are caused by genomic mutations and consequential altered gene expression…”
Get full text

Fluorescence-based detection of short DNA sequences under non-denaturing conditions by Smolina, Irina V., Kuhn, Heiko, Lee, Charles, Frank-Kamenetskii, Maxim D.

“…Different formats to detect the presence of short DNA marker sequences (20–30 bp) without denaturation of the DNA sample are presented. Duplex DNA is…”
Get full text

Fluorescence Imaging of Single-Copy DNA Sequences within the Human Genome Using PNA-Directed Padlock Probe Assembly by Yaroslavsky, Anastasia I., Smolina, Irina V.

“…We present an approach for fluorescent in situ detection of short, single-copy sequences within genomic DNA in human cells. The single-copy sensitivity and…”
Get full text

PNA openers and their applications for bacterial DNA diagnostics by Smolina, Irina V, Frank-Kamenetskii, Maxim D

“…The unique ability of triplex-forming PNAs to invade the double helix has made it possible to develop a highly specific and sensitive approach for bacterial…”
Get more information

End invasion of peptide nucleic acids (PNAs) with mixed-base composition into linear DNA duplexes by Smolina, Irina V., Demidov, Vadim V., Soldatenkov, Viatcheslav A., Chasovskikh, Sergey G., Frank-Kamenetskii, Maxim D.

“…Peptide nucleic acid (PNA) is a synthetic DNA mimic with valuable properties and a rapidly growing scope of applications. With the exception of recently…”
Get full text

Real-time monitoring of branched rolling-circle DNA amplification with peptide nucleic acid beacon by Smolina, Irina V., Demidov, Vadim V., Cantor, Charles R., Broude, Natalia E.

Get full text

High-density fluorescently labeled rolling-circle amplicons for DNA diagnostics by Smolina, Irina V., Cherny, Dmitry I., Nietupski, Raymond M., Beals, Thomas, Smith, James H., Lane, David J., Broude, Natalia E., Demidov, Vadim V.

Get full text

Pausing of DNA Polymerases on Duplex DNA Templates due to Ligand Binding in Vitro by Smolina, Irina V, Demidov, Vadim V, Frank-Kamenetskii, Maxim D

“…Using the recently developed peptide nucleic acid (PNA)-assisted assay, which makes it possible to extend a primer on duplex DNA, we study the…”
Get full text

End invasion of peptide nucleic acids (PNAs) with mixed-base composition into linear DNA duplexes by Smolina, Irina V., Demidov, Vadim V., Soldatenkov, Viatcheslav A., Chasovskikh, Sergey G., Frank-Kamenetskii, Maxim D.

“…Peptide nucleic acid (PNA) is a synthetic DNA mimic with valuable properties and a rapidly growing scope of applications. With the exception of recently…”
Get full text

An Artificial Primosome: Design, Function, and Applications by Demidov, Vadim V., Broude, Natalia E., Lavrentieva-Smolina, Irina V., Kuhn, Heiko, Frank-Kamenetskii, Maxim D.

“…Double‐stranded (ds) DNA is capable of the sequence‐specific accommodation of an additional oligodeoxyribonucleotide strand by the peptide nucleic…”
Get full text

Sequence-Universal Recognition of Duplex DNA by Oligonucleotides via Pseudocomplementarity and Helix Invasion by Smolina, Irina V, Demidov, Vadim V

“…The well-known Watson-Crick complementarity rules, which were discovered 50 years ago, elegantly direct the specific pairing of two DNA single strands. On the…”
Get full text

Fluorescence-based detection of short DNA sequences under non-denaturing conditions : Nucleic Acid Modification for Fluoescence-Based Technologies by SMOLINA, Irina V, KUHN, Heiko, LEE, Charles, FRANK-KAMENETSKII, Maxim D

Get full text

Peptide Nucleic Acid-Assisted Topological Labeling of Duplex DNA by Demidov, Vadim V., Kuhn, Heiko, Lavrentieva-Smolina, Irina V., Frank-Kamenetskii, Maxim D.

“…Peptide nucleic acids (PNAs) are a family of synthetic polyamide mimics of nucleic acids that offer a variety of applications. Pyrimidine bis-PNAs can be used…”
Get full text