Search Results - "Smolii, Oleg B."

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    Synthesis and in vitro evaluation of antibacterial and antibiofilm activities of novel triphenylphosphonium‐functionalized substituted pyrimidines by Muzychka, Liubov V., Humeniuk, Nataliia I., Boiko, Iryna O., Vrynchanu, Nina O., Smolii, Oleg B.

    Published in Chemical biology & drug design (01-02-2024)
    “…The increase in the prevalence of antibiotic‐resistant pathogens leads to a decrease in the number of antimicrobial agents for the treatment of infections and…”
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    Marine biomimetics: bromotyrosines loaded chitinous skeleton as source of antibacterial agents by Muzychka, Liubov, Voronkina, Alona, Kovalchuk, Valentine, Smolii, Oleg B., Wysokowski, Marcin, Petrenko, Iaroslav, Youssef, Diaa T. A., Ehrlich, Irina, Ehrlich, Hermann

    “…The marine sponges of the order Verongiida (Demospongiae: Porifera) have survived on our planet for more than 500 million years due to the presence of a unique…”
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    One‐Pot Synthesis of 6‐Aminopyrido[2,3‐d]pyrimidin‐7‐ones by Zinchenko, Anna M., Muzychka, Lyubov V., Kucher, Olexandr V., Sadkova, Iryna V., Mykhailiuk, Pavel K., Smolii, Oleg B.

    Published in European journal of organic chemistry (13-12-2018)
    “…One‐pot synthesis of 6‐aminopyrido[2,3‐d]pyrimidin‐7‐ones from 4‐aminopyrimidine‐5‐carbaldehydes and the in situ N‐protected methyl glycinate is developed. The…”
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    Synthesis, QSAR modeling, and molecular docking of novel fused 7-deazaxanthine derivatives as adenosine A 2A receptor antagonists by Muzychka, Liubov V, Verves, Evgenii V, Yaremchuk, Iryna O, Zinchenko, Anna M, Shishkina, Svitlana V, Semenyuta, Ivan V, Hodyna, Diana M, Metelytsia, Larysa O, Kovalishyn, Vasyl, Smolii, Oleg B

    Published in Chemical biology & drug design (01-12-2022)
    “…Predictive QSAR models for the search of new adenosine A receptor antagonists were developed by using OCHEM platform. The predictive ability of the regression…”
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    Synthesis and reactions of novel imidazo[4,5-b]pyridine building blocks by Dubina, Tetiana F., Kosarevych, Anton V., Kucher, Olexandr V., Sosunovych, Bohdan S., Smolii, Oleg B., Vashchenko, Bohdan V., Grygorenko, Oleksandr O.

    “…The synthesis of a novel imidazo[4,5- b ]pyridine and its partially saturated derivative relied on Michael addition of 1-methyl-1 H -imidazol-4-amine to…”
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    Pyrrolo[2,3-d]pyrimidine derivatives in the synthesis of a novel heterocyclic system 2a,5a,7-triazaacenaphthylene by Muzychka, Lyubov V., Yaremchuk, Iryna O., Verves, Evgenii V., Smolii, Oleg B.

    “…A convenient method for the synthesis of methyl 8-oxo-3 H ,8 H -2a,5a,7-triazaacenaphthylene-2-carboxylate by iodination of 7-allyl-4-methoxypyrrolo[2,3- d…”
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    Enzyme-Catalyzed Kinetic Resolution of 2,2,2-Trifluoro-1-(heteroaryl)ethanols: Experimental and Docking Studies by Kucher, Olexandr V., Kolodiazhnaya, Anastasiya O., Smolii, Oleg B., Prisuazhnyk, Dmytro V., Tolmacheva, Katerina A., Zaporozhets, Olga A., Moroz, Yurii S., Mykhailiuk, Pavel K., Tolmachev, Andrey A.

    Published in European journal of organic chemistry (01-12-2014)
    “…A convenient approach towards enantiopure (R) and (S) isomers of 2,2,2‐trifluoro‐1‐(heteroaryl)ethanols was developed. The enzyme‐catalyzed kinetic resolution…”
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    Synthesis of new 4-amino-substituted 7-iminopyrido[2,3-d]pyrimidines by Zinchenko, Anna N., Muzychka, Lyubov V., Biletskii, Igor I., Smolii, Oleg B.

    “…The reaction of 4,6-dichloropyrimidine-5-carbaldehyde with cyanomethyltriphenylphosphonium chloride gave (2 Е )-3-(4,6-dichloropyrimidin-5-yl)acrylonitrile,…”
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    Crystal structure of ( S )-1-(1,3-benzothiazol-2-yl)-2,2,2-trifluoroethanol by Shishkina, Svitlana V., Kucher, Olexandr V., Kolodiazhnaya, Anastasiya O., Smolii, Oleg B., Tolmachev, Andrey A.

    “…In the title compound, C 9 H 6 F 3 NOS, the 1,3-benzothiazole ring system is essentially planar, with an r.m.s. deviation of 0.006 Å. In the crystal, molecules…”
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    Synthesis and enzymatic resolution of novel analogs of alicyclic and heterocyclic mandelic acid derivatives by Sosunovych, Bohdan S., Timokhin, Oleksii S., Kucher, Olexandr V., Demianyk, Nadiia Y., Hys, Denys V., Zvarych, Yelyzaveta A., Smolii, Oleg B., Vashchenko, Bohdan V., Grygorenko, Oleksandr O.

    Published in Tetrahedron (17-07-2024)
    “…Synthesis and enzymatic resolution of a new class of alicyclic and heterocyclic mandelic acid derivatives was described. The method relied on the preparation…”
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    Synthesis of novel 1,2-dihydropyrrolo[1,2-a]pyrazin-1(2H)-one derivatives by Yaremchuk, Iryna O., Muzychka, Lyubov V., Smolii, Oleg B., Kucher, Olexandr V., Shishkina, Svitlana V.

    Published in Tetrahedron letters (31-01-2018)
    “…[Display omitted] •Wide range of novel 1,2-dihydropyrrolo[1,2-a]pyrazin-1(2H)-ones was synthesized.•The mechanism of oxazine to pyrazine transformation was…”
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    Lipase kinetic enantiomeric resolution of 1-heteroarylethanols by Kucher, Olexandr V., Kolodyazhnaya, Anastasiya O., Smolii, Oleg B., Nazarenko, Nadiya K., Kubyshkin, Vladimir, Mykhailiuk, Pavel K., Tolmachev, Andrey A.

    Published in Tetrahedron: asymmetry (01-05-2016)
    “…[Display omitted] The use of lipases offers a simple and straightforward method toward various chiral secondary alcohols. Here we examined the lipase…”
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    Crystal structure of (S)-1-(1,3-benzo-thia-zol-2-yl)-2,2,2-tri-fluoro-ethanol by Shishkina, Svitlana V, Kucher, Olexandr V, Kolodiazhnaya, Anastasiya O, Smolii, Oleg B, Tolmachev, Andrey A

    “…In the title compound, C9H6F3NOS, the 1,3-benzo-thia-zole ring system is essentially planar, with an r.m.s. deviation of 0.006 Å. In the crystal, mol-ecules…”
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    Enzymatic resolution of chroman-4-ol and its core analogues with Burkholderia cepacia lipase by Kucher, Olexandr V., Kolodyazhnaya, Anastasiya O., Smolii, Oleg B., Boiko, Alexandr I., Kubyshkin, Vladimir S., Mykhailiuk, Pavel K., Tolmachev, Andrey A.

    Published in Tetrahedron: asymmetry (15-04-2014)
    “…A convenient protocol for lipase resolution of chroman-4-ol and its analogues (six- and seven-membered rings with O, S, SO2) has been elaborated. The structure…”
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