Search Results - "Smolii, Oleg B."
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Express Method for Isolation of Ready-to-Use 3D Chitin Scaffolds from Aplysina archeri (Aplysineidae: Verongiida) Demosponge
Published in Marine drugs (22-02-2019)“…Sponges are a valuable source of natural compounds and biomaterials for many biotechnological applications. Marine sponges belonging to the order Verongiida…”
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Naturally Prefabricated Marine Biomaterials: Isolation and Applications of Flat Chitinous 3D Scaffolds from Ianthella labyrinthus (Demospongiae: Verongiida)
Published in International journal of molecular sciences (15-10-2019)“…Marine sponges remain representative of a unique source of renewable biological materials. The demosponges of the family Ianthellidae possess chitin-based…”
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3
Naturally Drug-Loaded Chitin: Isolation and Applications
Published in Marine drugs (10-10-2019)“…Naturally occurring three-dimensional (3D) biopolymer-based matrices that can be used in different biomedical applications are sustainable alternatives to…”
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New Source of 3D Chitin Scaffolds: The Red Sea Demosponge Pseudoceratina arabica (Pseudoceratinidae, Verongiida)
Published in Marine drugs (01-02-2019)“…The bioactive bromotyrosine-derived alkaloids and unique morphologically-defined fibrous skeleton of chitin origin have been found recently in marine…”
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Synthesis and in vitro evaluation of antibacterial and antibiofilm activities of novel triphenylphosphonium‐functionalized substituted pyrimidines
Published in Chemical biology & drug design (01-02-2024)“…The increase in the prevalence of antibiotic‐resistant pathogens leads to a decrease in the number of antimicrobial agents for the treatment of infections and…”
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Marine biomimetics: bromotyrosines loaded chitinous skeleton as source of antibacterial agents
Published in Applied physics. A, Materials science & processing (2021)“…The marine sponges of the order Verongiida (Demospongiae: Porifera) have survived on our planet for more than 500 million years due to the presence of a unique…”
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Synthesis, QSAR modeling, and molecular docking of novel fused 7‐deazaxanthine derivatives as adenosine A2A receptor antagonists
Published in Chemical biology & drug design (01-12-2022)“…Predictive QSAR models for the search of new adenosine A2A receptor antagonists were developed by using OCHEM platform. The predictive ability of the…”
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One‐Pot Synthesis of 6‐Aminopyrido[2,3‐d]pyrimidin‐7‐ones
Published in European journal of organic chemistry (13-12-2018)“…One‐pot synthesis of 6‐aminopyrido[2,3‐d]pyrimidin‐7‐ones from 4‐aminopyrimidine‐5‐carbaldehydes and the in situ N‐protected methyl glycinate is developed. The…”
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Synthesis, QSAR modeling, and molecular docking of novel fused 7-deazaxanthine derivatives as adenosine A 2A receptor antagonists
Published in Chemical biology & drug design (01-12-2022)“…Predictive QSAR models for the search of new adenosine A receptor antagonists were developed by using OCHEM platform. The predictive ability of the regression…”
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Synthesis and reactions of novel imidazo[4,5-b]pyridine building blocks
Published in Chemistry of heterocyclic compounds (New York, N.Y. 1965) (2024)“…The synthesis of a novel imidazo[4,5- b ]pyridine and its partially saturated derivative relied on Michael addition of 1-methyl-1 H -imidazol-4-amine to…”
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11
Pyrrolo[2,3-d]pyrimidine derivatives in the synthesis of a novel heterocyclic system 2a,5a,7-triazaacenaphthylene
Published in Chemistry of heterocyclic compounds (New York, N.Y. 1965) (01-05-2019)“…A convenient method for the synthesis of methyl 8-oxo-3 H ,8 H -2a,5a,7-triazaacenaphthylene-2-carboxylate by iodination of 7-allyl-4-methoxypyrrolo[2,3- d…”
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12
Enzyme-Catalyzed Kinetic Resolution of 2,2,2-Trifluoro-1-(heteroaryl)ethanols: Experimental and Docking Studies
Published in European journal of organic chemistry (01-12-2014)“…A convenient approach towards enantiopure (R) and (S) isomers of 2,2,2‐trifluoro‐1‐(heteroaryl)ethanols was developed. The enzyme‐catalyzed kinetic resolution…”
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Synthesis of new 4-amino-substituted 7-iminopyrido[2,3-d]pyrimidines
Published in Chemistry of heterocyclic compounds (New York, N.Y. 1965) (01-05-2017)“…The reaction of 4,6-dichloropyrimidine-5-carbaldehyde with cyanomethyltriphenylphosphonium chloride gave (2 Е )-3-(4,6-dichloropyrimidin-5-yl)acrylonitrile,…”
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Marine biomaterials: Biomimetic and pharmacological potential of cultivated Aplysina aerophoba marine demosponge
Published in Materials Science & Engineering C (01-04-2020)“…Marine demosponges of the Verongiida order are considered a gold-mine for bioinspired materials science and marine pharmacology. The aim of this work was to…”
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Crystal structure of ( S )-1-(1,3-benzothiazol-2-yl)-2,2,2-trifluoroethanol
Published in Acta crystallographica. Section E, Structure reports online (01-09-2014)“…In the title compound, C 9 H 6 F 3 NOS, the 1,3-benzothiazole ring system is essentially planar, with an r.m.s. deviation of 0.006 Å. In the crystal, molecules…”
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Synthesis and enzymatic resolution of novel analogs of alicyclic and heterocyclic mandelic acid derivatives
Published in Tetrahedron (17-07-2024)“…Synthesis and enzymatic resolution of a new class of alicyclic and heterocyclic mandelic acid derivatives was described. The method relied on the preparation…”
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Synthesis of novel 1,2-dihydropyrrolo[1,2-a]pyrazin-1(2H)-one derivatives
Published in Tetrahedron letters (31-01-2018)“…[Display omitted] •Wide range of novel 1,2-dihydropyrrolo[1,2-a]pyrazin-1(2H)-ones was synthesized.•The mechanism of oxazine to pyrazine transformation was…”
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18
Lipase kinetic enantiomeric resolution of 1-heteroarylethanols
Published in Tetrahedron: asymmetry (01-05-2016)“…[Display omitted] The use of lipases offers a simple and straightforward method toward various chiral secondary alcohols. Here we examined the lipase…”
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Crystal structure of (S)-1-(1,3-benzo-thia-zol-2-yl)-2,2,2-tri-fluoro-ethanol
Published in Acta crystallographica. Section E, Structure reports online (01-09-2014)“…In the title compound, C9H6F3NOS, the 1,3-benzo-thia-zole ring system is essentially planar, with an r.m.s. deviation of 0.006 Å. In the crystal, mol-ecules…”
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20
Enzymatic resolution of chroman-4-ol and its core analogues with Burkholderia cepacia lipase
Published in Tetrahedron: asymmetry (15-04-2014)“…A convenient protocol for lipase resolution of chroman-4-ol and its analogues (six- and seven-membered rings with O, S, SO2) has been elaborated. The structure…”
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