Search Results - "Smolenkova, Irina A"
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Inhibition of p300 histone acetyltransferase activity in palate mesenchyme cells attenuates Wnt signaling via aberrant E-cadherin expression
Published in Experimental cell research (01-03-2016)“…p300 is a multifunctional transcriptional coactivator that interacts with numerous transcription factors and exhibits protein/histone acetyltransferase…”
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Determinants of orofacial clefting II: Effects of 5-Aza-2′-deoxycytidine on gene methylation during development of the first branchial arch
Published in Reproductive toxicology (Elmsford, N.Y.) (01-01-2017)“…[Display omitted] •5-Aza-2′-deoxycytidine (AzaD) exposure induces cleft palate (CP) in mouse embryos.•AzaD exposure demethylates endogenous retroviral elements…”
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Determinants of orofacial clefting I: Effects of 5-Aza-2′-deoxycytidine on cellular processes and gene expression during development of the first branchial arch
Published in Reproductive toxicology (Elmsford, N.Y.) (01-01-2017)“…[Display omitted] •5-Aza-2′-deoxycytidine (AzaD) exposure induces cleft palate in mouse embryos.•AzaD reduces proliferation and induces apoptosis in first…”
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Gender-associated expression of tumor markers and a small gene set in breast carcinoma
Published in Breast (Edinburgh) (01-06-2014)“…Abstract Breast carcinomas in both genders share pathological features, although differences in incidence, prognosis and survival are reported. Expression of…”
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Epigenetic analysis of laser capture microdissected fetal epithelia
Published in Analytical biochemistry (01-11-2013)“…Laser capture microdissection (LCM) is a superior method for nondestructive collection of specific cell populations from tissue sections. Although DNA, RNA,…”
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Biosensors for detecting estrogen-like molecules and protein biomarkers
Published in Advances in experimental medicine and biology (2008)“…A novel evanescent-based biosensor (Endotect, ThreeFold Sensors, Inc.) was developed with laser-based fiber optics using fluorescent dye-labeled recombinant…”
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A three-tiered approach for calibration of a biosensor to detect estrogen mimics
Published in Advances in experimental medicine and biology (2008)“…A three-tiered approach was developed to determine the influence of a chemically-diverse group of compounds exhibiting estrogen mimicry using recombinant human…”
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Abstract 3457: Gender-associated expression of tumor markers and a small gene set in breast carcinoma
Published in Cancer research (Chicago, Ill.) (15-04-2013)“…In 2011, carcinoma of the breast in men accounted for ∼1% of all breast cancers in the US, and approximately 450 male patients died from this disease. Although…”
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Epigenetic Analysis of Laser Capture Microdissected Fetal Epithelia1
Published in Analytical biochemistry (30-07-2013)“…Laser capture microdissection (LCM) is a superior method for non-destructive collection of specific cell populations from tissue sections. While DNA, RNA and…”
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Expression of novel ERE‐binding proteins in human breast & uterine cells
Published in The FASEB journal (01-03-2006)“…While investigating ERE‐binding properties of estrogen receptor‐α (hERα) in human breast cancer cytosols, lower molecular weight ERE‐binding proteins (ERE‐BP)…”
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Predicting structural requirements of ligands with a multi‐tiered receptor‐based approach to assess estrogen mimicry
Published in The FASEB journal (01-03-2008)“…Abstract only Diverse chemical features of ligands binding to human estrogen receptor (hERα) illustrate promiscuity of the ligand binding domain (LBD) for…”
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Temporal Expression of miRNAs in Laser Capture Microdissected Palate Medial Edge Epithelium from Tgfβ3(-/-) Mouse Fetuses
Published in MicroRNA (Shariqah, United Arab Emirates) (2015)“…Clefting of the secondary palate is the most common birth defect in humans. Midline fusion of the bilateral palatal processes is thought to involve apoptosis,…”
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