Search Results - "Smolak, Pamela J"

A novel highly potent therapeutic antibody neutralizes multiple human chemokines and mimics viral immune modulation by Scalley-Kim, Michelle L, Hess, Bruce W, Kelly, Ryan L, Krostag, Anne-Rachel F, Lustig, Kurt H, Marken, John S, Ovendale, Pamela J, Posey, Aaron R, Smolak, Pamela J, Taylor, Janelle D L, Wood, C L, Bienvenue, David L, Probst, Peter, Salmon, Ruth A, Allison, Daniel S, Foy, Teresa M, Raport, Carol J

“…Chemokines play a key role in leukocyte recruitment during inflammation and are implicated in the pathogenesis of a number of autoimmune diseases. As such,…”
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Structure of a Soluble Secreted Chemokine Inhibitor vCCI (p35) from Cowpox Virus by Carfi, Andrea, Smith, Craig A., Smolak, Pamela J., McGrew, Jeffrey, Wiley, Don C.

“…Most poxviruses, including variola, the causative agent of smallpox, express a secreted protein of 35 kDa, vCCI, which binds CC-chemokines with high affinity…”
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The Novel Receptor TRAIL-R4 Induces NF-κB and Protects against TRAIL-Mediated Apoptosis, yet Retains an Incomplete Death Domain by Degli-Esposti, Mariapia A, Dougall, William C, Smolak, Pamela J, Waugh, Jennifer Y, Smith, Craig A, Goodwin, Raymond G

“…A fourth member of the emerging TRAIL receptor family, TRAIL-R4, has been cloned and characterized. TRAIL-R4 encodes a 386-amino acid protein with an…”
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Cloning and characterization of TRAIL-R3, a novel member of the emerging TRAIL receptor family by Degli-Esposti, M A, Smolak, P J, Walczak, H, Waugh, J, Huang, C P, DuBose, R F, Goodwin, R G, Smith, C A

“…TRAIL-R3, a new member of the TRAIL receptor family, has been cloned and characterized. TRAIL-R3 encodes a 299 amino acid protein with 58 and 54% overall…”
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Identification and characterization of a new member of the TNF family that induces apoptosis by Wiley, Steven R., Schooley, Ken, Smolak, Pamela J., Din, Wenie S., Huang, Chang-Pin, Nicholl, Jillian K., Sutherland, Grant R., Smith, Terri Davis, Rauch, Charles, Smith, Craig A., Goodwin, Raymond G.

“…A novel tumor necrosis factor (TNF) family member has been cloned and characterized. This protein, designated TNF-related apoptosis-Inducing ligand (TRAIL),…”
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Poxvirus Genomes Encode a Secreted, Soluble Protein That Preferentially Inhibits β Chemokine Activity yet Lacks Sequence Homology to Known Chemokine Receptors by Smith, Craig A., Smith, Terri Davis, Smolak, Pamela J., Friend, Della, Hagen, Heidi, Gerhart, Mary, Park, Linda, Pickup, David J., Torrance, Dauphine, Mohler, Ken, Schooley, Ken, Goodwin, Raymond G.

“…Poxvirus genomes encode several proteins which inhibit specific elements of the host immune response. We show the “35K” virulence gene in variola and cowpox…”
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Activation of the lymphotoxin beta receptor by cross-linking induces chemokine production and growth arrest in A375 melanoma cells by Degli-Esposti, MA, Davis-Smith, T, Din, WS, Smolak, PJ, Goodwin, RG, Smith, CA

“…The lymphotoxin beta receptor (LT beta R) was originally described as a transcribed sequence encoded on human chromosome 12p, with homology to the TNF receptor…”
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