Search Results - "Smitt, Peter A.E."
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The clinical spectrum of Caspr2 antibody–associated disease
Published in Neurology (02-08-2016)“…OBJECTIVE:To report a large cohort of patients with antibodies against contactin-associated protein-like 2 (Caspr2) and provide the clinical spectrum of this…”
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Evaluation of seizure treatment in anti-LGI1, anti-NMDAR, and anti-GABABR encephalitis
Published in Neurology (07-05-2019)“…OBJECTIVEThis nationwide cohort study evaluates seizure responses to immunotherapy and antiepileptic drugs (AEDs) in patients with anti-leucine-rich…”
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3
Long-term neuropsychological outcome following pediatric anti-NMDAR encephalitis
Published in Neurology (29-05-2018)“…OBJECTIVETo provide detailed long-term outcome data of children and adolescents following pediatric anti-N-methyl-D-aspartate receptor (anti-NMDAR)…”
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4
The relevance of VGKC positivity in the absence of LGI1 and Caspr2 antibodies
Published in Neurology (03-05-2016)“…OBJECTIVE:To assess the clinical relevance of a positive voltage-gated potassium channel (VGKC) test in patients lacking antibodies to LGI1 and Caspr2…”
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Intrinsic Gene Expression Profiles of Gliomas Are a Better Predictor of Survival than Histology
Published in Cancer research (Chicago, Ill.) (01-12-2009)“…Gliomas are the most common primary brain tumors with heterogeneous morphology and variable prognosis. Treatment decisions in patients rely mainly on…”
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A systematic review on barriers hindering adequate cancer pain management and interventions to reduce them: A critical appraisal
Published in European journal of cancer (1990) (01-05-2009)“…Abstract The aim of this paper is to identify the major barriers hindering adequate pain management and critically review interventions aiming to overcome…”
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A Hypermethylated Phenotype Is a Better Predictor of Survival than MGMT Methylation in Anaplastic Oligodendroglial Brain Tumors: A Report from EORTC Study 26951
Published in Clinical cancer research (15-11-2011)“…The MGMT promoter methylation status has been suggested to be predictive for outcome to temozolomide chemotherapy in patients with glioblastoma (GBM)…”
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8
SOX Antibodies in Small-Cell Lung Cancer and Lambert-Eaton Myasthenic Syndrome: Frequency and Relation With Survival
Published in Journal of clinical oncology (10-09-2009)“…SOX1 antibodies are common in small-cell lung carcinoma (SCLC) with and without paraneoplastic syndrome (PNS) and can serve as serological tumor marker…”
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Clinical Dutch-English Lambert-Eaton Myasthenic Syndrome (LEMS) Tumor Association Prediction Score Accurately Predicts Small-Cell Lung Cancer in the LEMS
Published in Journal of clinical oncology (01-03-2011)“…Approximately one half of patients with Lambert-Eaton myasthenic syndrome (LEMS) have small-cell lung carcinomas (SCLC), aggressive tumors with poor prognosis…”
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10
Anti-LGI1 encephalitis: Clinical syndrome and long-term follow-up
Published in Neurology (04-10-2016)“…OBJECTIVE:This nationwide study gives a detailed description of the clinical features and long-term outcome of anti–leucine-rich glioma-inactivated 1 (LGI1)…”
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The Effects of Analgesic Prescription and Patient Adherence on Pain in a Dutch Outpatient Cancer Population
Published in Journal of pain and symptom management (01-11-2007)“…Abstract Insufficient awareness of cancer pain, including breakthrough pain, inadequate analgesic prescriptions, and nonadherence contribute to inadequate…”
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Identification of Patients with Recurrent Glioblastoma Who May Benefit from Combined Bevacizumab and CCNU Therapy: A Report from the BELOB Trial
Published in Cancer research (Chicago, Ill.) (01-02-2016)“…The results from the randomized phase II BELOB trial provided evidence for a potential benefit of bevacizumab (beva), a humanized monoclonal antibody against…”
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13
Cerebellar degeneration associated with mGluR1 autoantibodies as a paraneoplastic manifestation of prostate adenocarcinoma
Published in Journal of neuroimmunology (15-10-2013)“…Abstract Subacute cerebellar degeneration associated with metabotropic glutamate receptor type 1 (mGluR1) autoantibodies is an uncommon syndrome known to be…”
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14
Immunotherapy in Glioblastoma: Current Shortcomings and Future Perspectives
Published in Cancers (22-03-2020)“…Glioblastomas are aggressive, fast-growing primary brain tumors. After standard-of-care treatment with radiation in combination with temozolomide, the overall…”
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Anti-NMDAR Encephalitis in the Netherlands, Focusing on Late-Onset Patients and Antibody Test Accuracy
Published in Neurology : neuroimmunology & neuroinflammation (01-03-2022)“…To describe the clinical features of anti-NMDAR encephalitis, emphasizing on late-onset patients and antibody test characteristics in serum and CSF. Nationwide…”
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Differential expression and prognostic significance of SOX genes in pediatric medulloblastoma and ependymoma identified by microarray analysis
Published in Neuro-oncology (Charlottesville, Va.) (01-10-2008)“…The objective of this study was to identify differentially expressed and prognostically important genes in pediatric medulloblastoma and pediatric ependymoma…”
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Intrinsic Molecular Subtypes of Glioma Are Prognostic and Predict Benefit From Adjuvant Procarbazine, Lomustine, and Vincristine Chemotherapy in Combination With Other Prognostic Factors in Anaplastic Oligodendroglial Brain Tumors: A Report From EORTC Study 26951
Published in Journal of clinical oncology (20-01-2013)“…Intrinsic glioma subtypes (IGSs) are molecularly similar tumors that can be identified based on unsupervised gene expression analysis. Here, we have evaluated…”
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18
Quantitative Proteomics and Metabolomics Analysis of Normal Human Cerebrospinal Fluid Samples
Published in Molecular & cellular proteomics (01-09-2010)“…The analysis of cerebrospinal fluid (CSF) is used in biomarker discovery studies for various neurodegenerative central nervous system (CNS) disorders. However,…”
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Alternative normalization and analysis pipeline to address systematic bias in NanoString GeoMx Digital Spatial Profiling data
Published in iScience (20-01-2023)“…Spatial transcriptomics is a novel technique that provides RNA-expression data with tissue-contextual annotations. Quality assessments of such techniques using…”
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antibody-based biomarker discovery method by mass spectrometry sequencing of complementarity determining regions
Published in Analytical and bioanalytical chemistry (01-01-2011)“…Autoantibodies are increasingly used as biomarkers in the detection of autoimmune disorders and cancer. Disease specific antibodies are generally detected by…”
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