Search Results - "Smits, W K"

Comparison of Whole-Genome Sequence-Based Methods and PCR Ribotyping for Subtyping of Clostridioides difficile by Baktash, A, Corver, J, Harmanus, C, Smits, W K, Fawley, W, Wilcox, M H, Kumar, N, Eyre, D W, Indra, A, Mellmann, A, Kuijper, E J

“…Clostridioides difficile is the most common cause of antibiotic-associated gastrointestinal infections. Capillary electrophoresis (CE)-PCR ribotyping is…”
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EUROmicroMOOC: using Twitter to share trends in Microbiology worldwide by López-Goñi, I, Giner-Lamia, J, Álvarez-Ordoñez, A, Benitez-Páez, Alfonso, Claessen, D, Cortesao, M, de Toro, M, García-Ruano, D, Granato, E T, Kovács, Á T, Romalde, J L, Sana, T G, Sánchez-Angulo, M, Sangari, F J, Smits, W K, Sturm, T, Thomassin, J L, Valdehuesa, K N G, Zapotoczna, M

“…Twitter is one of the most popular social media networks that, in recent years, has been increasingly used by researchers as a platform to share science and…”
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Single cell analysis of gene expression patterns of competence development and initiation of sporulation in Bacillus subtilis grown on chemically defined media by Veening, J.-W, Smits, W.K, Hamoen, L.W, Kuipers, O.P

“…Understanding the basis for the heterogeneous (or bistable) expression patterns of competence development and sporulation in Bacillus subtilis. Using flow…”
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MEK and PI3K-AKT inhibitors synergistically block activated IL7 receptor signaling in T-cell acute lymphoblastic leukemia by Canté-Barrett, K, Spijkers-Hagelstein, J A P, Buijs-Gladdines, J G C A M, Uitdehaag, J C M, Smits, W K, van der Zwet, J, Buijsman, R C, Zaman, G J R, Pieters, R, Meijerink, J P P

“…We identified mutations in the IL7Ra gene or in genes encoding the downstream signaling molecules JAK1, JAK3, STAT5B, N-RAS, K-RAS, NF1, AKT and PTEN in 49% of…”
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A healthy dietary pattern is associated with microbiota diversity in recently diagnosed bipolar patients: The Bipolar Netherlands Cohort (BINCO) study by Riedinger, M.A., Mesbah, R., Koenders, M., Henderickx, J.G.E., Smits, W.K., El Filali, E., Geleijnse, J.M., van der Wee, N.J.A., de Leeuw, M., Giltay, E.J.

“…Diet largely impacts the gut microbiota, and may affect mental and somatic health via the gut-brain axis. As such, the relationship between diet and the…”
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Distinct evolution of colistin resistance associated with experimental resistance evolution models in Klebsiella pneumoniae by Aulin, L B S, Koumans, C I M, Haakman, Y, van Os, W, Kraakman, M E M, Gooskens, J, Smits, W K, Liakopoulos, A, van Hasselt, J G C

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NOTCH1 and/or FBXW7 mutations predict for initial good prednisone response but not for improved outcome in pediatric T-cell acute lymphoblastic leukemia patients treated on DCOG or COALL protocols by Zuurbier, L, Homminga, I, Calvert, V, Winkel, ML te, Buijs-Gladdines, J G C A M, Kooi, C, Smits, W K, Sonneveld, E, Veerman, A J P, Kamps, W A, Horstmann, M, Petricoin, E F, Pieters, R, Meijerink, J P P

“…Aberrant activation of the NOTCH1 pathway by inactivating and activating mutations in NOTCH1 or FBXW7 is a frequent phenomenon in T-cell acute lymphoblastic…”
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Improving the predictive value of the competence transcription factor (ComK) binding site in Bacillus subtilis using a genomic approach by Hamoen, Leendert W., Smits, Wiep Klaas, Jong, Anne de, Holsappel, Siger, Kuipers, Oscar P.

“…Generally, the presence of a consensus sequence in the promoter of a gene is taken as indication for regulation by the transcription factor that binds to this…”
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P007 Neutrophil function in lesional biopsies is a strong determinant of IBD severity and may relate to an altered functional state already present in circulating cells by Pascutti, M F, Calado, B, Nugteren, S, Simons-Oosterhuis, Y, Smits, W K, Tuk, B, Hulleman-van Haaften, D H, Barendregt, D M H, Heredia, M, Klomberg, R C W, de Ridder, L, Samsom, J N

“…Abstract Background Neutrophils clear luminal bacteria from the intestinal lamina propria and have a protective role in Inflammatory Bowel Disease (IBD)…”
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Erratum: The vulvar microbiome in lichen sclerosus and high-grade intraepithelial lesions

“…[This corrects the article DOI: 10.3389/fmicb.2023.1264768.]…”
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P064 High intestinal Secretory Leukocyte Protease Inhibitor (SLPI) expression correlates with abundant neutrophilic inflammation and identifies Inflammatory Bowel Disease patients with a strong IL-17 response by Nugteren, S, Calado, B, Simons-Oosterhuis, Y, Hulleman-van Haaften, D H, Klomberg, R, Tuk, B, Charrout, M, Lindenbergh-Kortleve, D J, Smits, W K, Doukas, M, Sanders, M A, van Beek, G, Escher, J C, de Ridder, L, Samsom, J N

“…Abstract Background Inflammatory bowel disease, comprising Crohn’s disease (CD) and ulcerative colitis (UC), is driven by aberrant host-microbial immune…”
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Immature MEF2C-dysregulated T-cell leukemia patients have an early T-cell precursor acute lymphoblastic leukemia gene signature and typically have non-rearranged T-cell receptors by Zuurbier, Linda, Gutierrez, Alejandro, Mullighan, Charles G, Canté-Barrett, Kirsten, Gevaert, A Olivier, de Rooi, Johan, Li, Yunlei, Smits, Willem K, Buijs-Gladdines, Jessica G C A M, Sonneveld, Edwin, Look, A Thomas, Horstmann, Martin, Pieters, Rob, Meijerink, Jules P P

“…Three distinct immature T-cell acute lymphoblastic leukemia entities have been described including cases that express an early T-cell precursor immunophenotype…”
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The significance of PTEN and AKT aberrations in pediatric T-cell acute lymphoblastic leukemia by Zuurbier, Linda, Petricoin, 3rd, Emanuel F, Vuerhard, Maartje J, Calvert, Valerie, Kooi, Clarissa, Buijs-Gladdines, Jessica G C A M, Smits, Willem K, Sonneveld, Edwin, Veerman, Anjo J P, Kamps, Willem A, Horstmann, Martin, Pieters, Rob, Meijerink, Jules P P

“…PI3K/AKT pathway mutations are found in T-cell acute lymphoblastic leukemia, but their overall impact and associations with other genetic aberrations is…”
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Phenotypic variation in bacteria: the role of feedback regulation by Kuipers, Oscar P, Smits, Wiep Klaas, Veening, Jan-Willem

“…To survive in rapidly changing environmental conditions, bacteria have evolved a diverse set of regulatory pathways that govern various adaptive responses…”
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NOTCH1 and/or FBXW7 mutations predict for initial good prednisone response but not for improved outcome in pediatric T-cell acute lymphoblastic leukemia patients treated on DCOG or COALL protocols : Prognostic effects of NOTCH1 activing mutations in pediatrics T-ALL is treatment dependent by ZUURBIER, L, HOMMINGA, I, HORSTMANN, M, PETRICOIN, E. F, PIETERS, R, MEIJERINK, J. P. P, CALVERT, V, TE WINKEL, M. L, BUIJS-GLADDINES, J. G. C. A. M, KOOI, C, SMITS, W. K, SONNEVELD, E, VEERMAN, A. J. P, KAMPS, W. A

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Stripping Bacillus: ComK auto‐stimulation is responsible for the bistable response in competence development by Smits, Wiep Klaas, Eschevins, Caroline C., Susanna, Kim A., Bron, Sierd, Kuipers, Oscar P., Hamoen, Leendert W.

“…Summary In Bacillus subtilis competence for genetic transformation develops only in a subpopulation of cells in an isogenic culture. The molecular mechanisms…”
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Genome2D: a visualization tool for the rapid analysis of bacterial transcriptome data by Baerends, Richard J S, Smits, Wiep Klaas, de Jong, Anne, Hamoen, Leendert W, Kok, Jan, Kuipers, Oscar P

“…Genome2D is a Windows-based software tool for visualization of bacterial transcriptome and customized datasets on linear chromosome maps constructed from…”
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The Rok Protein of Bacillus subtilis Represses Genes for Cell Surface and Extracellular Functions by ALBANO, Mark, SMITS, Wiep Klaas, HO, Linh T. Y, KRAIGHER, Barbara, MANDIC-MULEC, Ines, KUIPERS, Oscar P, DUBNAU, David

“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Visualization of Differential Gene Expression by Improved Cyan Fluorescent Protein and Yellow Fluorescent Protein Production in Bacillus subtilis by VEENING, Jan-Willem, SMITS, Wiep Klaas, HAMOEN, Leendert W, JONGBLOED, Jan D. H, KUIPERS, Oscar P

“…Classifications Services AEM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Tricksy Business: Transcriptome Analysis Reveals the Involvement of Thioredoxin A in Redox Homeostasis, Oxidative Stress, Sulfur Metabolism, and Cellular Differentiation in Bacillus subtilis by SMITS, Wiep Klaas, DUBOIS, Jean-Yves F, BRON, Sierd, MAARTEN VAN DIJL, Jan, KUIPERS, Oscar P

“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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