Search Results - "Smith, Yvonne E"

Functional and molecular characterisation of EO771.LMB tumours, a new C57BL/6-mouse-derived model of spontaneously metastatic mammary cancer by Johnstone, Cameron N, Smith, Yvonne E, Cao, Yuan, Burrows, Allan D, Cross, Ryan S N, Ling, Xiawei, Redvers, Richard P, Doherty, Judy P, Eckhardt, Bedrich L, Natoli, Anthony L, Restall, Christina M, Lucas, Erin, Pearson, Helen B, Deb, Siddhartha, Britt, Kara L, Rizzitelli, Alexandra, Li, Jason, Harmey, Judith H, Pouliot, Normand, Anderson, Robin L

“…The translation of basic research into improved therapies for breast cancer patients requires relevant preclinical models that incorporate spontaneous…”
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Cleavage of the extracellular domain of junctional adhesion molecule-A is associated with resistance to anti-HER2 therapies in breast cancer settings by Leech, Astrid O, Vellanki, Sri HariKrishna, Rutherford, Emily J, Keogh, Aoife, Jahns, Hanne, Hudson, Lance, O'Donovan, Norma, Sabri, Siham, Abdulkarim, Bassam, Sheehan, Katherine M, Kay, Elaine W, Young, Leonie S, Hill, Arnold D K, Smith, Yvonne E, Hopkins, Ann M

“…Junctional adhesion molecule-A (JAM-A) is an adhesion molecule whose overexpression on breast tumor tissue has been associated with aggressive cancer…”
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Antibiotic Tetrocarcin-A Down-regulates JAM-A, IAPs and Induces Apoptosis in Triple-negative Breast Cancer Models by Vellanki, Sri Harikrishna, Cruz, Rodrigo G B, Richards, Cathy E, Smith, Yvonne E, Hudson, Lance, Jahns, Hanne, Hopkins, Ann M

“…Triple-negative breast cancers (TNBC) lack expression of three important receptors, and have limited treatment options. High expression of junctional adhesion…”
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Diterpenoid natural compound C4 (Crassin) exerts cytostatic effects on triple-negative breast cancer cells via a pathway involving reactive oxygen species by Richards, Cathy E., Vellanki, Sri H., Smith, Yvonne E., Hopkins, Ann M.

“…Purpose Triple-negative breast cancers (TNBC) lack expression of three common cell surface receptors, i.e., estrogen receptor (ER), progesterone receptor (PR)…”
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Functional Antagonism of Junctional Adhesion Molecule-A (JAM-A), Overexpressed in Breast Ductal Carcinoma In Situ (DCIS), Reduces HER2-Positive Tumor Progression by Smith, Yvonne E, Wang, Guannan, Flynn, Ciara L, Madden, Stephen F, MacEneaney, Owen, Cruz, Rodrigo G B, Richards, Cathy E, Jahns, Hanne, Brennan, Marian, Cremona, Mattia, Hennessy, Bryan T, Sheehan, Katherine, Casucci, Alexander, Sani, Faizah A, Hudson, Lance, Fay, Joanna, Vellanki, Sri H, O'Flaherty, Siobhan, Devocelle, Marc, Hill, Arnold D K, Brennan, Kieran, Sukumar, Saraswati, Hopkins, Ann M

“…Breast ductal carcinoma in situ (DCIS) is clinically challenging, featuring high diagnosis rates and few targeted therapies. Expression/signaling from…”
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Dynamic interplay between adhesion surfaces in carcinomas:Cell-cell and cell-matrix crosstalk by Smith, Yvonne E, Vellanki, Sri HariKrishna, Hopkins, Ann M

“…Cell-cell and cell-matrix signaling and communication between adhesion sites involve mechanisms which are required for cellular functions during normal…”
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Abstract P3-06-01: Junctional adhesion molecule-A (JAM-A) as a novel future drug target in ductal carcinoma in situ (DCIS) by Hopkins, Ann M, Smith, Yvonne E., Wang, Guannan, Flynn, Ciara, Casucci, Alexander, Vellanki, Sri HariKrishna, Hudson, Lance, Brennan, Kieran, Cremona, Mattia, Sukumar, Saraswati

“…Background/Aim: Increased expression of the cell-cell adhesion molecule Junctional Adhesion Molecule-A (JAM-A) has been associated with poor prognosis and HER2…”
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The Contribution of Ig-Superfamily and MARVEL D Tight Junction Proteins to Cancer Pathobiology by Vellanki, Sri HariKrishna, Richards, Cathy E., Smith, Yvonne E., Hopkins, Ann M.

“…The epithelial linings of eukaryotic organs form dynamically-regulated selectively-permeable barriers that control the movement of substances into (and out of)…”
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