Search Results - "Smith, Thomas C"

Large scale variation in the rate of germ-line de novo mutation, base composition, divergence and diversity in humans by Smith, Thomas C A, Arndt, Peter F, Eyre-Walker, Adam

“…It has long been suspected that the rate of mutation varies across the human genome at a large scale based on the divergence between humans and other species…”
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Optimal temperature for malaria transmission is dramatically lower than previously predicted by Mordecai, Erin A., Paaijmans, Krijn P., Johnson, Leah R., Balzer, Christian, Ben-Horin, Tal, de Moor, Emily, McNally, Amy, Pawar, Samraat, Ryan, Sadie J., Smith, Thomas C., Lafferty, Kevin D.

“…The ecology of mosquito vectors and malaria parasites affect the incidence, seasonal transmission and geographical range of malaria. Most malaria models to…”
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Reintroduction of resistant frogs facilitates landscape-scale recovery in the presence of a lethal fungal disease by Knapp, Roland A., Wilber, Mark Q., Joseph, Maxwell B., Smith, Thomas C., Grasso, Robert L.

“…Vast alteration of the biosphere by humans is causing a sixth mass extinction, driven in part by an increase in infectious diseases. The emergence of the…”
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A dynamic model for the efficiency optimization of an oscillatory low grade heat engine by Markides, Christos N., Smith, Thomas C.B.

“…A simple approach is presented for the modeling of complex oscillatory thermal-fluid systems capable of converting low grade heat into useful work. This…”
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Effectiveness of antifungal treatments during chytridiomycosis epizootics in populations of an endangered frog by Knapp, Roland A, Joseph, Maxwell B, Smith, Thomas C, Hegeman, Ericka E, Vredenburg, Vance T, Erdman, Jr, James E, Boiano, Daniel M, Jani, Andrea J, Briggs, Cheryl J

“…The recently-emerged amphibian chytrid fungus (Bd) has had an unprecedented impact on global amphibian populations, and highlights the urgent need to develop…”
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Correlation of Respiratory Physiologic Parameters in Mechanically Ventilated Coronavirus Disease 2019 Patients by Saha, Biplab K, Ghalib, Sana, Chieng, Hau, Pezzano, Chad, Lydon, Darren, Feustel, Paul, Smith, Thomas C, Chopra, Amit

“…Acute respiratory distress syndrome secondary to severe acute respiratory syndrome coronavirus-2 pneumonia or coronavirus disease 2019-related acute…”
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Declines and extinctions of mountain yellow‐legged frogs have small effects on benthic macroinvertebrate communities by Smith, Thomas C., Knapp, Roland A., Briggs, Cheryl J.

“…Species extinctions have the potential to dramatically reshape ecological communities. In the Sierra Nevada mountains of California, the emergence of a lethal…”
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Aquatic Soundscape Recordings Reveal Diverse Vocalizations and Nocturnal Activity of an Endangered Frog by Lapp, Sam, Smith, Thomas C, Knapp, Roland A, Lindauer, Alexa, Kitzes, Justin

“…AbstractAutonomous sensors provide opportunities to observe organisms across spatial and temporal scales that humans cannot directly observe. By processing…”
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Dyspnea in a 57-Year-Old Man With Recent Viral Illness by Chong, Woon H., Saha, Biplab, Ibrahim, Ammoura, Smith, Thomas C.

“…A 57-year-old man presented to the ED with a 1-month history of nonproductive cough and shortness of breath. The patient had been in his usual state of health…”
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A 67-Year-Old Woman With Progressive Dyspnea and Innumerous Pulmonary Nodules by Chieng, Hau, Saha, Biplab, Itty, Ria, Foulke, Llewellyn, Fantauzzi, John, Smith, Thomas C.

“…A 67-year-old woman, who recently immigrated to the United States from Afghanistan, presented to the hospital after sustaining a mechanical fall. She had no…”
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Host density has limited effects on pathogen invasion, disease‐induced declines and within‐host infection dynamics across a landscape of disease by Wilber, Mark Q., Knapp, Roland A., Smith, Thomas C., Briggs, Cheryl J.

“…1. Host density is hypothesized to be a major driver of variability in the responses and outcomes of wildlife populations following pathogen invasion. While…”
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Cannabinoid Oil Vaping-Associated Lung Injury and its Radiographic Appearance by Conuel, Edward J., Chieng, Hau C., Fantauzzi, John, Pokhrel, Kiran, Goldman, Chananya, Smith, Thomas C., Tiwari, Anupama, Chopra, Amit, Judson, Marc A.

“…Lung injury associated with cannabinoid oil vaping is rapidly becoming a serious public health concern. We describe the clinical and radiographic presentations…”
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Influence of Provider Type (Nurse Anesthetist or Resident Physician), Staff Assignments, and Other Covariates on Daily Evaluations of Anesthesiologists’ Quality of Supervision by Dexter, Franklin, Ledolter, Johannes, Smith, Thomas C., Griffiths, David, Hindman, Bradley J.

“…BACKGROUND:At many U.S. healthcare facilities, supervision of anesthesiology residents and/or Certified Registered Nurse Anesthetists (CRNAs) is a major daily…”
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Anesthesia Residents’ Global (Departmental) Evaluation of Faculty Anesthesiologists’ Supervision Can Be Less Than Their Average Evaluations of Individual Anesthesiologists by Hindman, Bradley J., Dexter, Franklin, Smith, Thomas C.

“…Faculty anesthesiologists' supervision of anesthesiology residents is required for both postgraduate medical education and billing compliance. Previously,…”
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Are sites with multiple single nucleotide variants in cancer genomes a consequence of drivers, hypermutable sites or sequencing errors? by Smith, Thomas C A, Carr, Antony M, Eyre-Walker, Adam C

“…Across independent cancer genomes it has been observed that some sites have been recurrently hit by single nucleotide variants (SNVs). Such recurrently hit…”
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Low-Dose Inhaled Nitric Oxide in Patients With Acute Lung Injury: A Randomized Controlled Trial by Taylor, Robert W, Zimmerman, Janice L, Dellinger, R. Phillip, Straube, Richard C, Criner, Gerard J, Davis, Jr, Kenneth, Kelly, Kathleen M, Smith, Thomas C, Small, Robert J, for the Inhaled Nitric Oxide in ARDS Study Group

“…CONTEXT Inhaled nitric oxide has been shown to improve oxygenation in acute lung injury. OBJECTIVE To evaluate the clinical efficacy of low-dose (5-ppm)…”
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Energy Cost of the Case Western Reserve Standing Neuroprosthesis by Forrest, George P., MD, Smith, Thomas C., MD, Triolo, Ronald J., PhD, Gagnon, Jason P., PT, DiRisio, Darryl, MD, Miller, Michael E., MS, Murray, Lori, PT, Davis, John A., MD, Iqbal, Atif, MD

“…Abstract Forrest GP, Smith TC, Triolo RJ, Gagnon JP, DiRisio D, Miller ME, Murray L, Davis JA, Iqbal A. Energy cost of the Case Western Reserve standing…”
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An inhibitor of neurite outgrowth produced by astrocytes by SMITH-THOMAS, L. C, FOK-SEANG, J, STEVENS, J, JIAN-SHENG DU, LUIR, E, FAISSNER, A, GELLER, H. M, ROGERS, J. H, FAWCETT, J. W

“…We have produced a number of astrocytic cell lines, some of which promote abundant neurite outgrowth, some of which are poor promoters of neurite outgrowth…”
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Nowhere to hide: impact of a temperature‐sensitive amphibian pathogen along an elevation gradient in the temperate zone by Knapp, Roland A., Briggs, Cheryl J., Smith, Thomas C., Maurer, Jeff R.

“…Amphibians are rapidly disappearing from habitats around the world and a major cause of these declines is the amphibian chytrid fungus, Batrachochytrium…”
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Effects of Low-Dose Fluticasone Propionate/Salmeterol Combination Therapy on Exhaled Nitric Oxide and Nitrite/Nitrate in Breath Condensates from Patients with Mild Persistent Asthma by Pasha, M. Asghar, Smith, Thomas C., Feustel, Paul J., Jourd'heuil, David

“…Objective. The long-acting β2-agonist salmeterol in combination with the corticosteroid fluticasone propionate is used in clinical practice for the treatment…”
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