Search Results - "Smith, Terika P."
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1
The functional organization of axonal mRNA transport and translation
Published in Nature reviews. Neuroscience (01-02-2021)“…Axons extend for tremendously long distances from the neuronal soma and make use of localized mRNA translation to rapidly respond to different extracellular…”
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2
The glycine arginine‐rich domain of the RNA‐binding protein nucleolin regulates its subcellular localization
Published in The EMBO journal (18-10-2021)“…Nucleolin is a multifunctional RNA Binding Protein (RBP) with diverse subcellular localizations, including the nucleolus in all eukaryotic cells, the plasma…”
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3
Intra-axonal translation of Khsrp mRNA slows axon regeneration by destabilizing localized mRNAs
Published in Nucleic acids research (10-06-2022)“…Abstract Axonally synthesized proteins support nerve regeneration through retrograde signaling and local growth mechanisms. RNA binding proteins (RBP) are…”
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4
Modulation of pain in pediatric sickle cell disease: Understanding the balance between endothelin mediated vasoconstriction and apelin mediated vasodilation
Published in Blood cells, molecules, & diseases (01-02-2015)“…Children with sickle cell disease (SCD) have painful vaso-occlusive episodes (VOEs), which often reoccur across the individual's lifespan. Vaso-constrictive…”
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Intra-axonal mechanisms driving axon regeneration
Published in Brain research (01-08-2020)“…•Axonal injury in the PNS invokes axon-to-soma signals through backpropaogating wave of Ca2+.•Increased axoplasmic Ca2+. ivates axonal Importin-β protein and…”
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6
Endothelin-1 induced desensitization in primary afferent neurons
Published in Neuroscience letters (17-10-2014)“…•ET-1 causes increase in Ca2+ transients in unprimed dorsal root ganglion neurons.•ET-1 priming has a desensitizing effect on subsequent exposures to…”
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Evidence for the endothelin system as an emerging therapeutic target for the treatment of chronic pain
Published in Journal of pain research (01-01-2014)“…Many people worldwide suffer from pain and a portion of these sufferers are diagnosed with a chronic pain condition. The management of chronic pain continues…”
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Injury-specific promoters enhance herpes simplex virus-mediated gene therapy for treating neuropathic pain in rodents
Published in The journal of pain (01-03-2015)“…Chronic neuropathic pain is often difficult to treat with current pain medications. Gene therapy is presently being explored as a therapeutic approach for the…”
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