Search Results - "Smith, T T"

High-coverage plasma lipidomics reveals novel sex-specific lipidomic fingerprints of age and BMI: Evidence from two large population cohort studies by Beyene, Habtamu B, Olshansky, Gavriel, T Smith, Adam Alexander, Giles, Corey, Huynh, Kevin, Cinel, Michelle, Mellett, Natalie A, Cadby, Gemma, Hung, Joseph, Hui, Jennie, Beilby, John, Watts, Gerald F, Shaw, Jonathan E, Moses, Eric K, Magliano, Dianna J, Meikle, Peter J

“…Obesity and related metabolic diseases show clear sex-related differences. The growing burden of these diseases calls for better understanding of the age- and…”
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Analysis of the structural diversity, substitution patterns, and frequency of nitrogen heterocycles among U.S. FDA approved pharmaceuticals by Vitaku, Edon, Smith, David T, Njardarson, Jon T

“…Nitrogen heterocycles are among the most significant structural components of pharmaceuticals. Analysis of our database of U.S. FDA approved drugs reveals that…”
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COVID-19 Severity Is Tripled in the Diabetes Community: A Prospective Analysis of the Pandemic's Impact in Type 1 and Type 2 Diabetes by Gregory, Justin M, Slaughter, James C, Duffus, Sara H, Smith, T Jordan, LeStourgeon, Lauren M, Jaser, Sarah S, McCoy, Allison B, Luther, James M, Giovannetti, Erin R, Boeder, Schafer, Pettus, Jeremy H, Moore, Daniel J

“…To quantify and contextualize the risk for coronavirus disease 2019 (COVID-19)-related hospitalization and illness severity in type 1 diabetes. We conducted a…”
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The association of sleep and pain: an update and a path forward by Finan, Patrick H, Goodin, Burel R, Smith, Michael T

“…Ample evidence suggests that sleep and pain are related. However, many questions remain about the direction of causality in their association, as well as…”
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Environment and Disease Risks by Rappaport, Stephen M., Smith, Martyn T.

“…A new paradigm is needed to assess how a lifetime of exposure to environmental factors affects the risk of developing chronic diseases. Although the risks of…”
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From Oxiranes to Oligomers: Architectures of U.S. FDA Approved Pharmaceuticals Containing Oxygen Heterocycles by Delost, Michael D, Smith, David T, Anderson, Benton J, Njardarson, Jon T

“…Oxygen heterocycles are the second most common type of heterocycles that appear as structural components of U.S. Food and Drug Administration (FDA) approved…”
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Advances in Understanding Benzene Health Effects and Susceptibility by SMITH, Martyn T

“…Benzene is a ubiquitous chemical in our environment that causes acute leukemia and probably other hematological cancers. Evidence for an association with…”
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Sex differences in measures of central sensitization and pain sensitivity to experimental sleep disruption: implications for sex differences in chronic pain by Smith, Jr, Michael T, Remeniuk, Bethany, Finan, Patrick H, Speed, Traci J, Tompkins, D Andrew, Robinson, Mercedes, Gonzalez, Kaylin, Bjurstrom, Martin F, Irwin, Michael R

“…Females demonstrate heightened central sensitization (CS), a risk factor for chronic pain characterized by enhanced responsivity of central nervous system…”
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Cortical visual area CSv as a cingulate motor area: a sensorimotor interface for the control of locomotion by Smith, Andrew T.

“…The response properties, connectivity and function of the cingulate sulcus visual area (CSv) are reviewed. Cortical area CSv has been identified in both human…”
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A Survey of the Structures of US FDA Approved Combination Drugs by Das, Pradipta, Delost, Michael D, Qureshi, Munaum H, Smith, David T, Njardarson, Jon T

“…Combination drugs are an important class of US FDA approved pharmaceuticals. These drugs have been on a continuous growth trajectory since the first…”
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The function of the sleep spindle: A physiological index of intelligence and a mechanism for sleep-dependent memory consolidation by FOGEL, Stuart M, SMITH, Carlyle T

“…Until recently, the electrophysiological mechanisms involved in strengthening new memories into a more permanent form during sleep have been largely unknown…”
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From Input to Output: The Lap c-di-GMP Biofilm Regulatory Circuit by Collins, Alan J, Smith, T. Jarrod, Sondermann, Holger, O'Toole, George A

“…Biofilms are the dominant bacterial lifestyle. The regulation of the formation and dispersal of bacterial biofilms has been the subject of study in many…”
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Letter to the editor regarding Bartalena et al. 2022 by Smith, T. J.

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The comorbidity of insomnia, chronic pain, and depression: Dopamine as a putative mechanism by Finan, Patrick H, Smith, Michael T

“…Summary Epidemiological, cross-sectional, and prospective studies suggest that insomnia, chronic pain, and depression frequently co-occur and are mutually…”
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Improved annotation of the domestic pig genome through integration of Iso-Seq and RNA-seq data by Beiki, H, Liu, H, Huang, J, Manchanda, N, Nonneman, D, Smith, T P L, Reecy, J M, Tuggle, C K

“…Our understanding of the pig transcriptome is limited. RNA transcript diversity among nine tissues was assessed using poly(A) selected single-molecule…”
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Emotion-Based Dispositions to Rash Action: Positive and Negative Urgency by Cyders, Melissa A, Smith, Gregory T

“…Under heightened emotional states, individuals are more inclined to engage in ill-considered or rash actions than at other times. The authors present evidence…”
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Type 1 Does the Two-Step: Type 1 Secretion Substrates with a Functional Periplasmic Intermediate by Smith, T Jarrod, Sondermann, Holger, O'Toole, George A

“…Bacteria have evolved several secretion strategies for polling and responding to environmental flux and insult. Of these, the type 1 secretion system (T1SS) is…”
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Wide field-of-view, multi-region, two-photon imaging of neuronal activity in the mammalian brain by Stirman, Jeffrey N, Smith, Ikuko T, Kudenov, Michael W, Smith, Spencer L

“…Simultaneous imaging of neural activity in large regions of the mouse brain at subcellular resolution is made possible with a wide field-of-view two-photon…”
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The Premotor theory of attention: Time to move on? by Smith, Daniel T., Schenk, Thomas

“…► We review evidence for the Premotor theory of attention. ► Contrary to Premotor theory, compelling converging evidence indicates that endogenous attention…”
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Supramolecular Tuning Enables Selective Oxygen Reduction Catalyzed by Cobalt Porphyrins for Direct Electrosynthesis of Hydrogen Peroxide by Smith, Peter T., Kim, Younghoon, Benke, Bahiru Punja, Kim, Kimoon, Chang, Christopher J.

“…We report a supramolecular strategy for promoting the selective reduction of O2 for direct electrosynthesis of H2O2. We utilized cobalt tetraphenylporphyrin…”
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