Search Results - "Smith, Shannon E."

Evolution and development of the chordates: collagen and pharyngeal cartilage by Rychel, Amanda L, Smith, Shannon E, Shimamoto, Heather T, Swalla, Billie J

“…Chordates evolved a unique body plan within deuterostomes and are considered to share five morphological characters, a muscular postanal tail, a notochord, a…”
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Blockade of CCL1 inhibits T regulatory cell suppressive function enhancing tumor immunity without affecting T effector responses by Hoelzinger, Dominique B, Smith, Shannon E, Mirza, Noweeda, Dominguez, Ana Lucia, Manrique, Soraya Zorro, Lustgarten, Joseph

“…Intratumoral accumulation of T regulatory cells (Tregs) creates an immunosuppressive environment that reduces the efficacy of antitumor immunotherapy. The…”
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Signals through 4-1BB inhibit T regulatory cells by blocking IL-9 production enhancing antitumor responses by Smith, Shannon E., Hoelzinger, Dominique B., Dominguez, Ana Lucia, Van Snick, Jacques, Lustgarten, Joseph

“…Previous studies from our laboratory indicate that intratumoral (i.t.) injections of CpG-ODN are the most effective adjuvant strategy to induce an antitumor…”
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A morphological and genetic characterization of metamorphosis in the ascidian Boltenia villosa by Davidson, Brad, Smith Wallace, Shannon E, Howsmon, Rebecca A, Swalla, Billie J

“…Ascidian metamorphosis is a critical life history stage for exploring chordate evolution and conserved chordate developmental signaling pathways. The vast…”
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Abstract 3610: GW182 associates with circulating microvesicles and microRNA in human plasma by Brown, Kirk, Millis, Meredith, Smith, Shannon E., Yeatts, Kim, Zhong, Jason, Stark, Adam, Kojima, Yuka, Garcia, Julie, Spetzler, David B.

“…Abstract To date, microRNAs (miR) in human plasma have been discovered within circulating microvesicles (cMV), bound to Argonaute 2 and associated with HDL and…”
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The impact of traumatic brain injury on memory performance within a forensic population by Smith, Shannon E

“…It is estimated that up to 4 million individuals within the United States experience some form of Traumatic Brain Injury annually. Unfortunately, due to…”
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Abstract 3607: Differential protein expression and miR content of sorted subsets of circulating microvesicles from cancer patients and healthy controls by Smith, Shannon E., Holterman, Daniel A., Brown, Kirk M., Duncan, Janet E., Zhong, Jason, Stark, Adam, Millis, Meredith, Tinder, Teresa, Spetzler, David

“…Abstract MicroRNAs (miRs) are small non-coding RNAs that are 20 to 25 nucleotides in length and regulate expression of entire families of genes. A major source…”
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Abstract 1568: Plasma-derived circulating microvesicles can both detect and help monitor breast cancer-related pathologies by Holterman, Daniel A., Duncan, Janet E., Deng, Ta, Smith, Shannon E., Spetzler, David B., Kuslich, Christine D.

“…Abstract Circulating microvesicles (cMV) are membrane-bound structures that play an important role in several biologic processes, including angiogenesis and…”
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Abstract 444: Subpopulations of circulating microvesicles have different microRNA profiles by Deng, Ta, Spetzler, David B., Holterman, Daniel, Pawlowski, Traci, Duncan, Janet E., Smith, Shannon E., Radebach, Katrina, LIttle, Tanya, Kuslich, Christine D.

“…Abstract The purpose of this study was to determine if circulating microvesicle (cMV) subpopulations as defined by surface protein composition also exhibit…”
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Combination of CpG-ODN+anti-4-1BB but not CpG-ODN+anti-OX40 enhances antitumor immune responses in neu mice modulating the inhibitory function of Tregs (40.7) by Smith, Shannon E, Hoelzinger, Dominique B, Dominguez, Ana Lucia, Lustgarten, Joseph

“…Abstract Previous studies have established that 4-1BB and OX40, members of the TNFR family, enhance antitumor immune responses. Recent studies from our…”
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CCL1: a novel therapeutic target for the modulation of Treg function: Implications for immmunotherapy of cancer (40.10) by Hoelzinger, Dominique B, Dominguez, Ana Lucia, Smith, Shannon E, Zorro Manrique, Soraya, Lustgarten, Joseph

“…Abstract Effective anti-tumor immunotherapy must overcome the immunosuppressive networks created by the tumor. Previous studies from our group indicate that…”
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Identification and characterization of macrophage regulatory cells (Mac-regs) with immunoregulatory properties (89.38) by Zorro Manrique, Soraya, Duque, Maria Adelaida, Dominguez, Ana Lucia, Mirza, Noweeda N, Hoelzinger, Dominique, Smith, Shannon E., Lustgarten, Joseph

“…Abstract Macrophages with suppressive characteristics such as Tumor associated macrophages or Myeloid derived suppressor cells have been defined showing…”
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