Search Results - "Smith, PEM"

Cenobamate for refractory epilepsy – Cardiff’s experience by BE, Schroeder, Michelle, Esposito, Lauren, Bruce, PEM, Smith, Khalid, Hamandi

“…BackgroundCenobamate is a newly licensed anti-seizure medication (ASM) for refractory epilepsy. We describe Cardiff’s experience.MethodsAll patients prescribed…”
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THUR 056 Juvenile myoclonic epilepsy in a tertiary centre – a database review by Marc, Edwards, PEM, Smith, Khalid, Hamandi

“…BackgroundJuvenile myoclonic epilepsy (JME) is generally thought to respond well to first line treatment but many patients continue to suffer with seizure…”
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Palinopsia by Smith, Philip EM, Shah, Pushkar, Sharpe, Jan, Todd, Anna, Goringe, Andrew P

“…Palinopsia (Greek palin, again and opsis, vision) is the symptom of persistent or recurrent visual images, following removal of the exciting stimulus.1 Our…”
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Cough responsiveness in neurogenic dysphagia by Smith, P E M, Wiles, C M

“…OBJECTIVES In neurogenic dysphagia a good cough is important for airway protection. If triggering of cough, or its effectiveness, is impaired this might result…”
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Ventilation and breathing pattern during sleep in Duchenne muscular dystrophy by Smith, P E, Edwards, R H, Calverley, P M

“…Ventilatory data, including timing and partitioning of ventilation, were obtained from six subjects with advanced Duchenne muscular dystrophy, aged 16 to 22…”
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PROMOTING FEEDBACK IN CLINICAL NEUROSCIENCE TEACHING by Anderson, J, Robertson, NP, Smith, PEM

“…Effective feedback promotes learning, improves future performance and enhances morale. Motivated adult learners will actively seek out constructive feedback…”
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A NOVEL LGI1 VARIANT IN LATERAL TEMPORAL LOBE EPILEPSY by Pickrell, WO, Hope, CHD, Higgins, AT, Mullins, JGL, Smith, PEM, Rees, MI, Chung, SK

“…BackgroundWe identified a family with autosomal dominant lateral temporal lobe epilepsy (ADLTLE). Given that LGI1 mutations account for around 50% of families…”
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SUDEP (SUDDEN UNEXPECTED DEATH IN EPILEPSY) FOLLOWING STATUS EPILEPTICUS by Lacey, AS, Smith, PEM, Rees, MI, Thomas, RH

“…Introduction Status epilepticus (SE) can be life-threatening in epilepsy. For some people however, SE is their first presentation of epilepsy and it is unclear…”
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FACTORS ASSOCIATED WITH EMERGENCY ATTENDANCES FOR EPILEPSY by Lynch, EC, Lacey, AS, Pickrell, WO, Smith, PEM, Rees, MI, Wardle, M

“…ObjectivesTo identify factors associated with emergency department (ED) attendance amongst patients with epilepsy.MethodsLinked electronic primary care and ED…”
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Detecting Vigabatrin Toxicity by Imaging of the Retinal Nerve Fiber Layer by Wild, John M, Robson, Catherine R, Jones, Adrian L, Cunliffe, Ian A, Smith, Philip E. M

“…To quantify retinal nerve fiber layer thickness (RNFLT) and macular thickness (MT) in patients exhibiting vigabatrin-attributed visual field loss (VAVFL) and…”
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Mechanisms of sleep-disordered breathing in chronic neuromuscular disease: implications for management by Smith, P E, Edwards, R H, Calverley, P M

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Awake seizures after pure sleep-related epilepsy: a systematic review and implications for driving law by Thomas, R H, King, W H, Johnston, J A, Smith, P E M

“…Who with sleep seizures is safe to drive? Driving law is controversial; ineligibility varies between individual US states and EU countries. Current UK driving…”
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Variability of antiepileptic medication taking behaviour in sudden unexplained death in epilepsy: hair analysis at autopsy by Williams, J, Lawthom, C, Dunstan, F D, Dawson, T P, Kerr, M P, Wilson, J F, Smith, P E M

“…Background: Variable compliance with antiepileptic drugs (AEDs) is a potentially preventable cause of sudden unexplained death in epilepsy (SUDEP). Hair AED…”
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Adjunctive therapy versus alternative monotherapy in patients with partial epilepsy failing on a single drug: a multicentre, randomised, pragmatic controlled trial by Beghi, Ettore, Gatti, Giuliana, Tonini, Clara, Ben-Menachem, Elinor, Chadwick, David W, Nikanorova, Marina, Gromov, Sergei A, Smith, Philip E.M, Specchio, Luigi M, Perucca, Emilio

“…Objective: To evaluate the value of alternative monotherapy versus adjunctive therapy in partial epilepsy refractory to single antiepileptic drug (AED)…”
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Clinical recommendations for oxcarbazepine by Smith, P.E.M

“…Oxcarbazepine (OXC) is indicated for treating partial-onset and generalized tonic–clonic seizures, in both adults and children aged over 6 years, as…”
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Ocular complications of neurological therapy by Hadjikoutis, S., Morgan, J. E., Wild, J. M., Smith, P. E. M.

“…Treatments used for several neurological conditions may adversely affect the eye. Vigabatrin‐related retinal toxicity leads to a visual field defect. Optic…”
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Levetiracetam as add-on therapy in generalised epilepsies by Kumar, S.Pradeep, Smith, Philip E.M.

“…Levetiracetam is highly effective as add-on treatment in refractory partial-onset seizures but there are only limited data supporting its benefit in…”
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Progressive mitochondrial disease resulting from a novel missense mutation in the mitochondrial DNA ND3 gene by Taylor, Robert W., Singh-Kler, Rajinder, Hayes, Christine M., Smith, Philip E.M., Turnbull, Douglass M.

“…We describe a 42‐year‐old man who presented with a progressive history of epilepsy, stroke‐like episodes, bilateral optic atrophy, and cognitive decline…”
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Self‐discontinuation of Antiepileptic Medication in Pregnancy: Detection by Hair Analysis by Williams, John, Myson, Vicki, Steward, Sandra, Jones, Glenda, Wilson, John F., Kerr, Michael P., Smith, Philip E.M.

“…Purpose: Concerns over teratogenicity of antiepileptic drugs (AEDs) during pregnancy must be balanced against the risks of seizures to the mother and…”
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A teenager epilepsy clinic: observational study by Smith, P. E. M., Myson, V., Gibbon, F.

“…Teenagers with epilepsy are a group with special needs whom we have specifically targeted in our clinical practice. All teenagers referred to our unit between…”
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