Search Results - "Smith, Orla M."
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Comparison of standard and accelerated initiation of renal replacement therapy in acute kidney injury
Published in Kidney international (01-10-2015)“…In patients with severe acute kidney injury (AKI) but no urgent indication for renal replacement therapy (RRT), the optimal time to initiate RRT remains…”
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Effect of oral chlorhexidine de-adoption and implementation of an oral care bundle on mortality for mechanically ventilated patients in the intensive care unit (CHORAL): a multi-center stepped wedge cluster-randomized controlled trial
Published in Intensive care medicine (01-11-2021)“…Purpose Oral chlorhexidine is used widely for mechanically ventilated patients to prevent pneumonia, but recent studies show an association with excess…”
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Reverse Triggering Dyssynchrony 24 h after Initiation of Mechanical Ventilation
Published in Anesthesiology (Philadelphia) (01-05-2021)“…Reverse triggering is a delayed asynchronous contraction of the diaphragm triggered by passive insufflation by the ventilator in sedated mechanically…”
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Relationship of catheter-associated urinary tract infection to mortality and length of stay in critically ill patients: A systematic review and meta-analysis of observational studies
Published in Critical care medicine (01-05-2011)“…OBJECTIVE:To determine whether catheter-associated urinary tract infections are associated with increased morbidity and mortality in critically ill patients…”
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Role Incongruence and Psychological Stress Symptoms in Substitute Decision Makers of Intensive Care Patients
Published in American journal of critical care (01-07-2020)“…BACKGROUNDMost intensive care patients require substitute decision makers (SDMs) to make decisions. The SDMs may prefer an active, shared, or passive…”
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Standard versus accelerated initiation of renal replacement therapy in acute kidney injury (STARRT-AKI): study protocol for a randomized controlled trial
Published in Trials (05-10-2013)“…Acute kidney injury is a common and devastating complication of critical illness, for which renal replacement therapy is frequently needed to manage severe…”
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Characteristics, clinical course, and outcomes of homeless and non-homeless patients admitted to ICU: A retrospective cohort study
Published in PloS one (12-06-2017)“…Little is known about homeless patients in intensive care units (ICUs). To compare clinical characteristics, treatments, and outcomes of homeless to…”
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Feasibility of the electrolarynx for enabling communication in the chronically critically ill: The EECCHO study
Published in Journal of critical care (01-10-2018)“…To assess feasibility of producing intelligible and comprehensible speech with an electrolarynx; measure anxiety, communication ease, and satisfaction…”
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Protocol for a multi-centered, stepped wedge, cluster randomized controlled trial of the de-adoption of oral chlorhexidine prophylaxis and implementation of an oral care bundle for mechanically ventilated critically ill patients: the CHORAL study
Published in Current controlled trials in cardiovascular medicine (24-10-2019)“…Routine application of chlorhexidine oral rinse is recommended to reduce risk of ventilator-associated pneumonia (VAP) in mechanically ventilated patients…”
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A mixed-methods systematic review protocol to examine the use of physical restraint with critically ill adults and strategies for minimizing their use
Published in Systematic reviews (21-11-2016)“…Critically ill patients frequently experience severe agitation placing them at risk of harm. Physical restraint is common in intensive care units (ICUs) for…”
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Expanding the 3 Wishes Project for compassionate end-of-life care: a qualitative evaluation of local adaptations
Published in BMC palliative care (30-06-2020)“…The 3 Wishes Project (3WP) is an end-of-life program that honors the dignity of dying patients by fostering meaningful connections among patients, families,…”
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LAMP shines a light on Zika virus
Published in Science (American Association for the Advancement of Science) (05-05-2017)Get full text
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Whole-blood neutrophil gelatinase-associated lipocalin to predict adverse events in acute kidney injury: A prospective observational cohort study
Published in Journal of critical care (01-12-2015)“…Abstract Purpose Acute kidney injury is common in intensive care units and is associated with increased morbidity and mortality. We evaluated the ability of…”
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An antimalarial to add to the armamentarium
Published in Science (American Association for the Advancement of Science) (28-04-2017)Get full text
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Mapping a path to HIV elimination
Published in Science (American Association for the Advancement of Science) (31-03-2017)Get full text
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Deferred consent in a minimal-risk study involving critically ill subarachnoid hemorrhage patients
Published in Canadian respiratory journal (01-09-2014)“…Alterations from first-party and surrogate decision-maker consent can enhance the feasibility of research involving critically ill patients. To describe the…”
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Wonder
Published in Science (18-12-2015)“…Wonder is a new, environmentally themed exhibition that heralds the opening of the elegantly refurbished Renwick gallery. Wonder Renwick Gallery of the…”
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A patient's progress
Published in Science (18-12-2015)“…They say that each event that happens to you prepares you for the next step on life's journey. The award-winning journalist Jon Palfreman, best known for his…”
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Book Review Journal Article -
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Rates and determinants of informed consent: A case study of an international thromboprophylaxis trial
Published in Journal of critical care (01-02-2013)“…Abstract Background Successful completion of randomized trials depends upon efficiently and ethically screening patients and obtaining informed consent…”
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Long-acting drug to treat resistant malaria
Published in Science (American Association for the Advancement of Science) (17-07-2015)Get full text
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