Search Results - "Smith, Nicholas A."

Epstein-Barr-Virus-Induced One-Carbon Metabolism Drives B Cell Transformation by Wang, Liang Wei, Shen, Hongying, Nobre, Luis, Ersing, Ina, Paulo, Joao A., Trudeau, Stephen, Wang, Zhonghao, Smith, Nicholas A., Ma, Yijie, Reinstadler, Bryn, Nomburg, Jason, Sommermann, Thomas, Cahir-McFarland, Ellen, Gygi, Steven P., Mootha, Vamsi K., Weekes, Michael P., Gewurz, Benjamin E.

“…Epstein-Barr virus (EBV) causes Burkitt, Hodgkin, and post-transplant B cell lymphomas. How EBV remodels metabolic pathways to support rapid B cell outgrowth…”
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Modulation of host cell signaling during cytomegalovirus latency and reactivation by Smith, Nicholas A, Chan, Gary C, O'Connor, Christine M

“…Human cytomegalovirus (HCMV) resides latently in cells of the myeloid compartment, including CD34 hematopoietic progenitor cells and circulating monocytes…”
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A Novel Human Skin Tissue Model To Study Varicella-Zoster Virus and Human Cytomegalovirus by Lloyd, Megan G, Smith, Nicholas A, Tighe, Michael, Travis, Kelsey L, Liu, Dongmei, Upadhyaya, Prashant K, Kinchington, Paul R, Chan, Gary C, Moffat, Jennifer F

“…The herpesviruses varicella-zoster virus (VZV) and human cytomegalovirus (HCMV) are endemic to humans. VZV causes varicella (chicken pox) and herpes zoster…”
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Key residues in the VDAC2-BAK complex can be targeted to modulate apoptosis by Yuan, Zheng, van Delft, Mark F, Li, Mark Xiang, Sumardy, Fransisca, Smith, Brian J, Huang, David C S, Lessene, Guillaume, Khakam, Yelena, Jin, Ruitao, He, Sitong, Smith, Nicholas A, Birkinshaw, Richard W, Czabotar, Peter E, Dewson, Grant

“…BAK and BAX execute intrinsic apoptosis by permeabilising the mitochondrial outer membrane. Their activity is regulated through interactions with pro-survival…”
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Identification of an activation site in Bak and mitochondrial Bax triggered by antibodies by Iyer, Sweta, Anwari, Khatira, Alsop, Amber E., Yuen, Wai Shan, Huang, David C. S., Carroll, John, Smith, Nicholas A., Smith, Brian J., Dewson, Grant, Kluck, Ruth M.

“…During apoptosis, Bak and Bax are activated by BH3-only proteins binding to the α2–α5 hydrophobic groove; Bax is also activated via a rear pocket. Here we…”
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A systematic review of the evidence for single stage and two stage revision of infected knee replacement by Masters, James P M, Smith, Nicholas A, Foguet, Pedro, Reed, Mike, Parsons, Helen, Sprowson, Andrew P

“…Periprosthetic infection about the knee is a devastating complication that may affect between 1% and 5% of knee replacement. With over 79 000 knee replacements…”
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Fish-hunting cone snail venoms are a rich source of minimized ligands of the vertebrate insulin receptor by Ahorukomeye, Peter, Disotuar, Maria M, Gajewiak, Joanna, Karanth, Santhosh, Watkins, Maren, Robinson, Samuel D, Flórez Salcedo, Paula, Smith, Nicholas A, Smith, Brian J, Schlegel, Amnon, Forbes, Briony E, Olivera, Baldomero, Hung-Chieh Chou, Danny, Safavi-Hemami, Helena

“…The fish-hunting marine cone snail uses a specialized venom insulin to induce hypoglycemic shock in its prey. We recently showed that this venom insulin,…”
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Multisensory object perception in infancy: 4-month-olds perceive a mistuned harmonic as a separate auditory and visual object by Smith, Nicholas A., Folland, Nicole A., Martinez, Diana M., Trainor, Laurel J.

“…Infants learn to use auditory and visual information to organize the sensory world into identifiable objects with particular locations. Here we use a…”
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Oral sensitization to whey proteins induces age- and sex-dependent behavioral abnormality and neuroinflammatory responses in a mouse model of food allergy: a potential role of mast cells by Germundson, Danielle L, Smith, Nicholas A, Vendsel, Lane P, Kelsch, Andrea V, Combs, Colin K, Nagamoto-Combs, Kumi

“…Growing evidence has strengthened the association of food allergy with neuropsychiatric symptoms such as depression, anxiety, and autism. However, underlying…”
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Supramolecular Assemblies Formed on an Epitaxial Graphene Superstructure by Pollard, Andrew J, Perkins, Edward W, Smith, Nicholas A, Saywell, Alex, Goretzki, Gudrun, Phillips, Anna G, Argent, Stephen P, Sachdev, Hermann, Müller, Frank, Hüfner, Stefan, Gsell, Stefan, Fischer, Martin, Schreck, Matthias, Osterwalder, Jürg, Greber, Thomas, Berner, Simon, Champness, Neil R, Beton, Peter H

“…Quite comparable: A graphene monolayer is used as a substrate for the growth of two‐dimensional hydrogen‐bonded supramolecular structures (see STM image). The…”
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Infant-Directed Speech Is Modulated by Infant Feedback by Smith, Nicholas A., Trainor, Laurel J.

“…When mothers engage in infant‐directed (ID) speech, their voices change in a number of characteristic ways, including adopting a higher overall pitch. Studies…”
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Astrogliosis Associated With Behavioral Abnormality in a Non-anaphylactic Mouse Model of Cow's Milk Allergy by Smith, Nicholas A, Germundson, Danielle L, Combs, Colin K, Vendsel, Lane P, Nagamoto-Combs, Kumi

“…Etiology of neuropsychiatric disorders is complex, involving multiple factors that can affect the type and severity of symptoms. Although precise causes are…”
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HLA-II Alleles Influence Physical and Behavioral Responses to a Whey Allergen in a Transgenic Mouse Model of Cow's Milk Allergy by Germundson, Danielle L, Nookala, Suba, Smith, Nicholas A, Warda, Yassmine, Nagamoto-Combs, Kumi

“…The symptoms of food allergies vary significantly between individuals, likely due to genetic determinants. In humans, allergy development is initiated by…”
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Epstein-Barr virus genetic variation in lymphoblastoid cell lines derived from Kenyan pediatric population by Simbiri, Kenneth O, Smith, Nicholas A, Otieno, Richard, Wohlford, Eric E M, Daud, Ibrahim I, Odada, Sumba P, Middleton, Frank, Rochford, Rosemary

“…Epstein-Barr virus (EBV) is associated with Burkitt's lymphoma (BL), and in regions of sub-Saharan Africa where endemic BL is common, both the EBV Type 1…”
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Asymptomatic sensitization to a cow's milk protein induces sustained neuroinflammation and behavioral changes with chronic allergen exposure by Brishti, Afrina, Germundson-Hermanson, Danielle L, Smith, Nicholas A, Kearney, Angela E, Warda, Yassmine, Nagamoto-Combs, Kumi

“…Mouse models of food allergy have contributed to our understanding of various aspects of the disease, including susceptibilities, symptom spectra, cellular…”
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Soccer-Related Injuries Treated in Emergency Departments: 1990-2014 by Smith, Nicholas A, Chounthirath, Thiphalak, Xiang, Huiyun

“…To investigate the epidemiology of youth soccer-related injuries treated in emergency departments in the United States. A retrospective analysis was conducted…”
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Sex-Based Division of Labor Is a Form of Cooperation that Constrains both Males and Females by Smith, Nicholas M. A., von Hippel, William

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CD21 (Complement Receptor 2) Is the Receptor for Epstein-Barr Virus Entry into T Cells by Smith, Nicholas A, Coleman, Carrie B, Gewurz, Benjamin E, Rochford, Rosemary

“…Epstein-Barr virus (EBV) is associated with a number of T-cell diseases, including some peripheral T-cell lymphomas, hemophagocytic lymphohistiocytosis, and…”
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In Vitro Particle Image Velocity Measurements in a Model Root Canal: Flow around a Polymer Rotary Finishing File by Koch, Jon D., PhD, Smith, Nicholas A., BSME, Garces, Daniel, BSME, Gao, Luyang, BSME, Olsen, F. Kris, DDS, MS

“…Abstract Introduction Root canal irrigation is vital to thorough debridement and disinfection, but the mechanisms that contribute to its effectiveness are…”
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Induction of Hypersensitivity with Purified Beta-Lactoglobulin as a Mouse Model of Cow's Milk Allergy by Smith, Nicholas A, Nagamoto-Combs, Kumi

“…Cow's milk allergy is one of the most prevalent food allergies in both children and adults. As dairy products are common dietary ingredients and the prevalence…”
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