Search Results - "Smith, Malisa T."
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Validation of a CD1b tetramer assay for studies of human mycobacterial infection or vaccination
Published in Journal of immunological methods (01-07-2018)“…CD1 tetramers loaded with lipid antigens facilitate the identification of rare lipid-antigen specific T cells present in human blood and tissue. Because CD1…”
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Durable Expansion of TCR-δ Meta-Clonotypes After BCG Revaccination in Humans
Published in Frontiers in immunology (30-03-2022)“…bacille Calmette-Guérin (BCG) has been used for 100 years and prevents disseminated tuberculosis and death in young children. However, it shows only partial…”
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Comorbid illnesses are associated with altered adaptive immune responses to SARS-CoV-2
Published in JCI insight (22-03-2021)“…Comorbid medical illnesses, such as obesity and diabetes, are associated with more severe COVID-19, hospitalization, and death. However, the role of the immune…”
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IFN-γ-independent immune markers of Mycobacterium tuberculosis exposure
Published in Nature medicine (01-06-2019)“…Exposure to Mycobacterium tuberculosis ( Mtb ) results in heterogeneous clinical outcomes including primary progressive tuberculosis and latent Mtb infection…”
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A Randomized, Double-Blinded, Placebo-Controlled, Phase 1 Study of a Replication-Defective Herpes Simplex Virus (HSV) Type 2 Vaccine, HSV529, in Adults With or Without HSV Infection
Published in The Journal of infectious diseases (09-08-2019)“…Herpes simplex virus 2 (HSV2) causes genital herpes in >400 million persons worldwide. We conducted a randomized, double-blinded, placebo-controlled trial of a…”
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Nasal and blood transcriptomic pathways underpinning the clinical response to grass pollen immunotherapy
Published in Journal of allergy and clinical immunology (01-11-2023)“…Allergen immunotherapy (AIT) is a well-established disease-modifying therapy for allergic rhinitis, yet the fundamental mechanisms underlying its clinical…”
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T Cells Specific for a Mycobacterial Glycolipid Expand after Intravenous Bacillus Calmette-Guérin Vaccination
Published in The Journal of immunology (1950) (15-03-2021)“…Intradermal vaccination with bacillus Calmette-Guérin (BCG) protects infants from disseminated tuberculosis, and i.v. BCG protects nonhuman primates (NHP)…”
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Specific CD4+ T cell phenotypes associate with bacterial control in people who ‘resist’ infection with Mycobacterium tuberculosis
Published in Nature immunology (01-08-2024)“…A subset of individuals exposed to Mycobacterium tuberculosis ( Mtb ) that we refer to as ‘resisters’ (RSTR) show evidence of IFN-γ − T cell responses to Mtb…”
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Conservation of molecular and cellular phenotypes of invariant NKT cells between humans and non-human primates
Published in Immunogenetics (New York) (01-07-2019)“…Invariant NKT (iNKT) cells in both humans and non-human primates are activated by the glycolipid antigen, α-galactosylceramide (α-GalCer). However, the extent…”
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IFN-γ independent markers of Mycobacterium tuberculosis exposure among male South African gold miners
Published in EBioMedicine (01-07-2023)“…The prevalence of tuberculosis among men who work in the gold mines of South Africa is among the highest in the world, but a fraction of miners demonstrate…”
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Publisher Correction: IFN-γ-independent immune markers of Mycobacterium tuberculosis exposure
Published in Nature medicine (01-07-2019)“…In the version of this article originally published, there was an error in the abstract. The word disease should not have been included in the sentence “These…”
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MR1-restricted T cell clonotypes are associated with "resistance" to Mycobacterium tuberculosis infection
Published in JCI insight (08-05-2024)“…T cells are required for protective immunity against Mycobacterium tuberculosis. We recently described a cohort of Ugandan household contacts of tuberculosis…”
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Type-1 Interferon and Th2-Type Gene Expression Responses and Childhood Asthma
Published in Journal of allergy and clinical immunology (01-02-2019)Get full text
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MR1-restricted T cell clonotypes are associated with resistance to Mycobacterium tuberculosis infection
Published in The Journal of immunology (1950) (01-05-2023)“…Abstract T-cells are a critical facet of the adaptive immune system and have been shown in both human and animal studies to be essential for control of…”
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Publisher Correction: IFN-[gamma]-independent immune markers of Mycobacterium tuberculosis exposure
Published in Nature medicine (01-07-2019)“…In the version of this article originally published, there was an error in the abstract. The word disease should not have been included in the sentence "These…”
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IFN-[gamma]-independent immune markers of Mycobacterium tuberculosis exposure
Published in Nature medicine (01-06-2019)“…Exposure to Mycobacterium tuberculosis (Mtb) results in heterogeneous clinical outcomes including primary progressive tuberculosis and latent Mtb infection…”
Get full text
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IFN-γ independent markers of Mycobacterium tuberculosis exposure among male South African gold minersResearch in context
Published in EBioMedicine (01-07-2023)“…Background: The prevalence of tuberculosis among men who work in the gold mines of South Africa is among the highest in the world, but a fraction of miners…”
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