Search Results - "Smith, Lois E"
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Retinopathy of prematurity
Published in The Lancet (British edition) (26-10-2013)“…Summary The immature retinas of preterm neonates are susceptible to insults that disrupt neurovascular growth, leading to retinopathy of prematurity…”
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Through The Eyes of a Child : Understanding Retinopathy through ROP The Friedenwald Lecture
Published in Investigative ophthalmology & visual science (01-12-2008)Get full text
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A mechanosensitive transcriptional mechanism that controls angiogenesis
Published in Nature (26-02-2009)“…Angiogenesis is controlled by physical interactions between cells and extracellular matrix as well as soluble angiogenic factors, such as VEGF. However, the…”
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Optimization of an Image-Guided Laser-Induced Choroidal Neovascularization Model in Mice
Published in PloS one (10-07-2015)“…The mouse model of laser-induced choroidal neovascularization (CNV) has been used in studies of the exudative form of age-related macular degeneration using…”
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Retinopathy of prematurity
Published in Angiogenesis (London) (01-06-2007)“…Retinopathy of prematurity (ROP) is a common blinding disease in children in the developed world despite current treatment, and is becoming increasingly…”
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Therapeutic Effects of Anti-Inflammatory and Anti-Oxidant Nutritional Supplementation in Retinal Ischemic Diseases
Published in International journal of molecular sciences (18-05-2024)“…Appropriate nutrients are essential for cellular function. Dietary components can alter the risk of systemic metabolic diseases, including cardiovascular…”
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Effect of Enteral Lipid Supplement on Severe Retinopathy of Prematurity: A Randomized Clinical Trial
Published in JAMA pediatrics (01-04-2021)“…Lack of arachidonic acid (AA) and docosahexaenoic acid (DHA) after extremely preterm birth may contribute to preterm morbidity, including retinopathy of…”
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Vitreous metabolomics profiling of proliferative diabetic retinopathy
Published in Diabetologia (01-01-2021)“…Aims/hypothesis Proliferative diabetic retinopathy (PDR) with retinal neovascularisation (NV) is a leading cause of vision loss. This study identified a set of…”
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Retinopathy of prematurity: Metabolic risk factors
Published in eLife (24-11-2022)“…At preterm birth, the retina is incompletely vascularized. Retinopathy of prematurity (ROP) is initiated by the postnatal suppression of physiological retinal…”
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Müller glial responses compensate for degenerating photoreceptors in retinitis pigmentosa
Published in Experimental & molecular medicine (01-11-2021)“…Photoreceptor degeneration caused by genetic defects leads to retinitis pigmentosa, a rare disease typically diagnosed in adolescents and young adults. In most…”
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Inflammatory signals from photoreceptor modulate pathological retinal angiogenesis via c-Fos
Published in The Journal of experimental medicine (05-06-2017)“…Pathological neovessels growing into the normally avascular photoreceptors cause vision loss in many eye diseases, such as age-related macular degeneration and…”
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Prognostic Value of Parenteral Nutrition Duration on Risk of Retinopathy of Prematurity: Development and Validation of the Revised DIGIROP Clinical Decision Support Tool
Published in JAMA ophthalmology (01-08-2023)“…The prognostic impact of parenteral nutrition duration (PND) on retinopathy of prematurity (ROP) is not well studied. Safe prediction models can help optimize…”
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Low birth weight is a risk factor for severe retinopathy of prematurity depending on gestational age
Published in PloS one (15-10-2014)“…To evaluate the impact of low birth weight as a risk factor for retinopathy of prematurity (ROP) that will require treatment in correlation with gestational…”
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FGF21 via mitochondrial lipid oxidation promotes physiological vascularization in a mouse model of Phase I ROP
Published in Angiogenesis (London) (01-08-2023)“…Hyperglycemia in early postnatal life of preterm infants with incompletely vascularized retinas is associated with increased risk of potentially blinding…”
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Current update on retinopathy of prematurity: screening and treatment
Published in Current opinion in pediatrics (01-04-2011)“…Despite current treatments, retinopathy of prematurity (ROP) remains a major cause of blindness in premature infants and the incidence is increasing with…”
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Ischemic neurons prevent vascular regeneration of neural tissue by secreting semaphorin 3A
Published in Blood (02-06-2011)“…The failure of blood vessels to revascularize ischemic neural tissue represents a significant challenge for vascular biology. Examples include proliferative…”
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Short-term Outcomes After Very Low-Dose Intravitreous Bevacizumab for Retinopathy of Prematurity
Published in JAMA ophthalmology (01-06-2020)“…Intravitreous bevacizumab (0.25 mg to 0.625 mg) is commonly used to treat type 1 retinopathy of prematurity (ROP), but there are concerns about systemic…”
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Suppression of Retinal Neovascularization by Erythropoietin siRNA in a Mouse Model of Proliferative Retinopathy
Published in Investigative ophthalmology & visual science (01-03-2009)“…Erythropoietin (EPO), an oxygen-regulated hormone stimulating erythrocyte production, was recently found to be critical for retinal angiogenesis. EPO mRNA…”
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Choroid sprouting assay: an ex vivo model of microvascular angiogenesis
Published in PloS one (26-07-2013)“…Angiogenesis of the microvasculature is central to the etiology of many diseases including proliferative retinopathy, age-related macular degeneration and…”
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Tailored vs Static Oxygen Saturation Targets to Prevent Retinopathy of Prematurity
Published in JAMA ophthalmology (01-04-2019)Get more information
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