Search Results - "Smith, Laurie"
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The influence of sex, gender, age, and ethnicity on psychosocial factors and substance use throughout phases of the COVID-19 pandemic
Published in PloS one (22-11-2021)“…The SARS-CoV-2 (COVID-19) pandemic has had profound physical and mental health effects on populations around the world. Limited empirical research has used a…”
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Integration of omic networks in a developmental atlas of maize
Published in Science (American Association for the Advancement of Science) (19-08-2016)“…Coexpression networks and gene regulatory networks (GRNs) are emerging as important tools for predicting functional roles of individual genes at a system-wide…”
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HPV Extended Genotyping to Triage Abnormal Cervical Cancer Screens-Balancing the Harms and Benefits of an Additional Triage Test before Direct Colposcopy Referral
Published in Cancer epidemiology, biomarkers & prevention (01-08-2024)“…The Netherlands' cervical cancer screening program transitioned to primary human papillomavirus (HPV) screening in 2017. After the introduction of HPV-based…”
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Effect of Screening With Primary Cervical HPV Testing vs Cytology Testing on High-grade Cervical Intraepithelial Neoplasia at 48 Months: The HPV FOCAL Randomized Clinical Trial
Published in JAMA : the journal of the American Medical Association (03-07-2018)“…IMPORTANCE: There is limited information about the relative effectiveness of cervical cancer screening with primary human papillomavirus (HPV) testing alone…”
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Rapid whole genome sequencing and precision neonatology
Published in Seminars in perinatology (01-12-2015)“…Abstract Traditionally, genetic testing has been too slow or perceived to be impractical to initial management of the critically ill neonate. Technological…”
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Intention to receive a COVID-19 vaccine: results from a population-based survey in Canada
Published in BMC public health (29-05-2021)“…Abstract Background The success of any COVID-19 vaccine program ultimately depends on high vaccine uptake. This study determined overall intention to receive a…”
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Eurogin roadmap 2017: Triage strategies for the management of HPV‐positive women in cervical screening programs
Published in International journal of cancer (15-08-2018)“…Cervical cancer screening will rely, increasingly, on HPV testing as a primary screen. The requirement for triage tests which can delineate clinically…”
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Constructing functional cuticles: analysis of relationships between cuticle lipid composition, ultrastructure and water barrier function in developing adult maize leaves
Published in Annals of botany (08-01-2020)“…Prior work has examined cuticle function, composition and ultrastructure in many plant species, but much remains to be learned about how these features are…”
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Effectiveness of exome and genome sequencing guided by acuity of illness for diagnosis of neurodevelopmental disorders
Published in Science translational medicine (03-12-2014)“…Neurodevelopmental disorders (NDDs) affect more than 3% of children and are attributable to single-gene mutations at more than 1000 loci. Traditional methods…”
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Community-integrated self-collected HPV-based cervix screening in a low-resource rural setting: a pragmatic, cluster-randomized trial
Published in Nature medicine (01-04-2023)“…Effective approaches to improve coverage of self-collected human papillomavirus (HPV)-based cervix screening (SCS) as well as attendance at treatment for…”
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Evaluation of a validated methylation triage signature for human papillomavirus positive women in the HPV FOCAL cervical cancer screening trial
Published in International journal of cancer (15-05-2019)“…Human papillomavirus (HPV)‐based cervical cancer screening requires triage of HPV positive women to identify those at risk of cervical intraepithelial…”
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Hyperpolarised xenon magnetic resonance spectroscopy for the longitudinal assessment of changes in gas diffusion in IPF
Published in Thorax (01-05-2019)“…Prognosticating idiopathic pulmonary fibrosis (IPF) is challenging, in part due to a lack of sensitive biomarkers. A recent article in described how…”
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STAAR: a randomised controlled trial of electronic adherence monitoring with reminder alarms and feedback to improve clinical outcomes for children with asthma
Published in Thorax (01-04-2017)“…Suboptimal adherence to inhaled steroids is common in children with asthma and is associated with poor disease control, reduced quality of life and even death…”
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A genome sequencing system for universal newborn screening, diagnosis, and precision medicine for severe genetic diseases
Published in American journal of human genetics (01-09-2022)“…Newborn screening (NBS) dramatically improves outcomes in severe childhood disorders by treatment before symptom onset. In many genetic diseases, however,…”
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Reconstruction of protein networks from an atlas of maize seed proteotypes
Published in Proceedings of the National Academy of Sciences - PNAS (03-12-2013)“…A comprehensive knowledge of proteomic states is essential for understanding biological systems. Using mass spectrometry, we mapped an atlas of developing…”
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Attitudes and Preferences Regarding Non–Clinic-Based Self-Collection for Sexually Transmitted Infection Testing Among Clinic Attendees in British Columbia, Canada
Published in Sexually transmitted diseases (01-01-2022)“…Sexually transmitted infections (STIs) are a global epidemic; although screening programs reduce transmission, barriers, including access and stigma, hinder…”
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Whole-genome sequencing for identification of Mendelian disorders in critically ill infants: a retrospective analysis of diagnostic and clinical findings
Published in The lancet respiratory medicine (01-05-2015)“…Summary Background Genetic disorders and congenital anomalies are the leading causes of infant mortality. Diagnosis of most genetic diseases in neonatal and…”
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Integrating GWAS and TWAS to elucidate the genetic architecture of maize leaf cuticular conductance
Published in Plant physiology (Bethesda) (01-08-2022)“…Abstract The cuticle, a hydrophobic layer of cutin and waxes synthesized by plant epidermal cells, is the major barrier to water loss when stomata are closed…”
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Strategies to accelerate the elimination of cervical cancer in British Columbia, Canada: a modelling study
Published in Canadian Medical Association journal (CMAJ) (03-06-2024)“…To eliminate cervical cancer in Canada by 2040, defined as an annual age-standardized incidence rate (ASIR) lower than 4.0 per 100 000 women, the Canadian…”
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Divergent Roles for Maize PAN1 and PAN2 Receptor-Like Proteins in Cytokinesis and Cell Morphogenesis
Published in Plant physiology (Bethesda) (01-04-2014)“…Pangloss1 (PANI) and PAN2 are leucine-rich repeat receptor-like proteins that function cooperatively to polarize the divisions of subsidiary mother cells…”
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