Search Results - "Smith, L. Cody"

Adverse outcome pathway networks I: Development and applications by Knapen, Dries, Angrish, Michelle M., Fortin, Marie C., Katsiadaki, Ioanna, Leonard, Marc, Margiotta‐Casaluci, Luigi, Munn, Sharon, O'Brien, Jason M., Pollesch, Nathan, Smith, L. Cody, Zhang, Xiaowei, Villeneuve, Daniel L.

“…Based on the results of a Horizon Scanning exercise sponsored by the Society of Environmental Toxicology and Chemistry that focused on advancing the adverse…”
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Adverse outcome pathway networks II: Network analytics by Villeneuve, Daniel L., Angrish, Michelle M., Fortin, Marie C., Katsiadaki, Ioanna, Leonard, Marc, Margiotta‐Casaluci, Luigi, Munn, Sharon, O'Brien, Jason M., Pollesch, Nathan L., Smith, L. Cody, Zhang, Xiaowei, Knapen, Dries

“…Toxicological responses to stressors are more complex than the simple one‐biological‐perturbation to one‐adverse‐outcome model portrayed by individual adverse…”
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Transforming growth factor beta1 targets estrogen receptor signaling in bronchial epithelial cells by Smith, L Cody, Moreno, Santiago, Robertson, Lauren, Robinson, Sarah, Gant, Kristal, Bryant, Andrew J, Sabo-Attwood, Tara

“…Sex differences in idiopathic pulmonary fibrosis (IPF) suggest a protective role for estrogen (E2); however, mechanistic studies in animal models have produced…”
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Transcriptional profiling of lung macrophages during pulmonary injury induced by nitrogen mustard by Smith, L. Cody, Venosa, Alessandro, Gow, Andrew J., Laskin, Jeffrey D., Laskin, Debra L.

“…Nitrogen mustard (NM) and sulfur mustard are cytotoxic alkylating agents that cause severe and progressive damage to the respiratory tract. Evidence indicates…”
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The G Protein-Coupled Estrogen Receptor Agonist G-1 Inhibits Nuclear Estrogen Receptor Activity and Stimulates Novel Phosphoproteomic Signatures by Smith, L Cody, Ralston-Hooper, Kimberly J, Ferguson, P Lee, Sabo-Attwood, Tara

“…Estrogen exerts cellular effects through both nuclear (ESR1 and ESR2) and membrane-bound estrogen receptors (G-protein coupled estrogen receptor, GPER);…”
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Brief hyperoxia increases mitochondrial oxidation and increases phosphodiesterase 5 activity in fetal pulmonary artery smooth muscle cells by Farrow, Kathryn N, Lee, Keng Jin, Perez, Marta, Schriewer, Jacqueline M, Wedgwood, Stephen, Lakshminrusimha, Satyan, Smith, Cody L, Steinhorn, Robin H, Schumacker, Paul T

“…Oxygen is a pulmonary vasodilator, but data suggest high O(2) concentrations impede that response. We previously reported 24 h of 100% O(2) increased…”
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Overcoming qRT-PCR interference by select carbon nanotubes in assessments of gene expression by Humes, Sara T, Hentschel, Shannon, Lavelle, Candice M, Smith, L Cody, Lednicky, John A, Saleh, Navid B, Sabo-Attwood, Tara

“…Nanomaterials (NMs) of various types, including carbon nanotubes (CNTs), can interfere with standard quantitative real-time PCR (qRT-PCR) assays, resulting in…”
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Macrophage activation in the lung during the progression of nitrogen mustard induced injury is associated with histone modifications and altered miRNA expression by Venosa, Alessandro, Smith, L. Cody, Gow, Andrew J., Zarbl, Helmut, Laskin, Jeffrey D., Laskin, Debra L.

“…Activated macrophages have been implicated in lung injury and fibrosis induced by the cytotoxic alkylating agent, nitrogen mustard (NM). Herein, we determined…”
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Hydroxyl functionalized multi-walled carbon nanotubes modulate immune responses without increasing 2009 pandemic influenza A/H1N1 virus titers in infected mice by Chen, Hao, Humes, Sara T., Rose, Melanie, Robinson, Sarah E., Loeb, Julia C., Sabaraya, Indu V., Smith, L. Cody, Saleh, Navid B., Castleman, William L., Lednicky, John A., Sabo-Attwood, Tara

“…Growing use of carbon nanotubes (CNTs) have garnered concerns regarding their association with adverse health effects. Few studies have probed how CNTs affect…”
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Multi-walled carbon nanotubes inhibit estrogen receptor expression in vivo and in vitro through transforming growth factor beta1 by Smith, L Cody, Moreno, Santiago, Robinson, Sarah, Orandle, Marlene, Porter, Dale W, Das, Dipesh, Saleh, Navid B, Sabo-Attwood, Tara

“…Exposure to multi-walled carbon nanotubes (MWCNTs) is suspected to contribute to pulmonary fibrosis through modulation of transforming growth factor beta1…”
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Differential recruitment of co-regulatory proteins to the human estrogen receptor 1 in response to xenoestrogens by Smith, L. Cody, Clark, Jessica C., Bisesi, Joseph H., Ferguson, P. Lee, Sabo-Attwood, Tara

“…The diverse biological effects of xenoestrogens may be explained by their ability to differentially recruit co-regulatory proteins to the estrogen receptor…”
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From the Community to the Laboratory: Field Research to Advance Student Learning by Guerrier, Richardson, Doherty, Cathleen, Smith, L. Cody, Pivnick, Elyse, Aleksunes, Lauren, Buckley, Brian, Laskin, Debra

“…Fieldwork is an integral component of learning science, but is often overlooked while performing laboratory research. During the summer, a community outreach…”
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Transcriptional profiling of lung macrophages following ozone exposure in mice identifies signaling pathways regulating immunometabolic activation by Smith, Ley Cody, Abramova, Elena, Vayas, Kinal, Rodriguez, Jessica, Gelfand-Titiyevksiy, Benjamin, Roepke, Troy A, Laskin, Jeffrey D, Gow, Andrew J, Laskin, Debra L

“…Abstract Macrophages play a key role in ozone-induced lung injury by regulating both the initiation and resolution of inflammation. These distinct activities…”
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Screening Cucurbit Rootstocks for Resistance to Meloidogyne spp. and Rotylenchulus reniformis by Smith, Cody L., Freeman, Joshua H., Kokalis-Burelle, Nancy, Wechter, William P.

“…Fusarium wilt [caused by the fungus Fusarium oxysporum f. sp. niveum (FON)] has been a consistent problem in watermelon [ Citrullus lanatus (Thunb.) Matsum…”
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