Search Results - "Smith, Kyle A."

Acute exercise mobilizes NKT-like cells with a cytotoxic transcriptomic profile but does not augment the potency of cytokine-induced killer (CIK) cells by Zúñiga, Tiffany M., Baker, Forrest L., Smith, Kyle A., Batatinha, Helena, Lau, Branden, Gustafson, Michael P., Katsanis, Emmanuel, Simpson, Richard J.

“…CD3 + /CD56 + Natural killer (NK) cell-like T-cells (NKT-like cells) represent <5% of blood lymphocytes, display a cytotoxic phenotype, and can kill various…”
Get full text

Regulatory Dendritic Cells Induced by Bendamustine Are Associated With Enhanced Flt3 Expression and Alloreactive T-Cell Death by Molina, Megan S, Hoffman, Emely A, Stokes, Jessica, Kummet, Nicole, Smith, Kyle A, Baker, Forrest, Zúñiga, Tiffany M, Simpson, Richard J, Katsanis, Emmanuel

“…The growth factor Flt3 ligand (Flt3L) is central to dendritic cell (DC) homeostasis and development, controlling survival and expansion by binding to Flt3…”
Get full text

Mental health, physical symptoms and biomarkers of stress during prolonged exposure to Antarctica's extreme environment by Alfano, Candice A., Bower, Joanne L., Connaboy, Christopher, Agha, Nadia H., Baker, Forrest L., Smith, Kyle A., So, Christine J., Simpson, Richard J.

“…The Antarctic environment is characterized by many of the same extreme stressors as long-duration space flight (LDSE), thereby providing a useful earth-based…”
Get full text

Human lymphocytes mobilized with exercise have an anti-tumor transcriptomic profile and exert enhanced graft-versus-leukemia effects in xenogeneic mice by Batatinha, Helena, Diak, Douglass M, Niemiro, Grace M, Baker, Forrest L, Smith, Kyle A, Zúñiga, Tiffany M, Mylabathula, Preteesh L, Seckeler, Michael D, Lau, Branden, LaVoy, Emily C, Gustafson, Michael P, Katsanis, Emmanuel, Simpson, Richard J

“…Every bout of exercise mobilizes and redistributes large numbers of effector lymphocytes with a cytotoxic and tissue migration phenotype. The frequent…”
Get full text

COVID-19 vaccination produces exercise-responsive SARS-CoV-2 specific T-cells regardless of infection history by Smith, Kyle A., Zúñiga, Tiffany M., Baker, Forrest L., Batatinha, Helena, Pedlar, Charles R., Burgess, Shane C., Gustafson, Michael P., Katsanis, Emmanuel, Simpson, Richard J.

“…•Acute exercise after vaccination robustly mobilized SARS-CoV-2–specific T-cells to blood in an intensity-dependent manner.•The synthetic immunity group…”
Get full text

Acute exercise increases immune responses to SARS CoV-2 in a previously infected man by Baker, Forrest L., Smith, Kyle A., Zúñiga, Tiffany M., Batatinha, Helena, Niemiro, Grace M., Pedlar, Charles R., Burgess, Shane C., Katsanis, Emmanuel, Simpson, Richard J.

“…Evidence is emerging that exercise and physical activity provides protection against severe COVID-19 disease in patients infected with SARS-CoV-2, but it is…”
Get full text

Exercise mobilizes diverse antigen specific T-cells and elevates neutralizing antibodies in humans with natural immunity to SARS CoV-2 by Baker, Forrest L., Zúñiga, Tiffany M., Smith, Kyle A., Batatinha, Helena, Kulangara, Terese S., Seckeler, Michael D., Burgess, Shane C., Katsanis, Emmanuel, Simpson, Richard J.

“…Epidemiological data suggest that physical activity protects against severe COVID-19 and improves clinical outcomes, but how exercise augments the SARS-CoV-2…”
Get full text

Spontaneous intracranial hypotension: Targeted or blind blood patch by Smith, Kyle A

“…Highlights • Patients with new onset postural headache should be referred to neurology or neurosurgery for workup. • Individual epidural blood patches (EBPs)…”
Get full text

National Rates, Causes, Risk Factors, and Outcomes Associated With 30-Day and 90-Day Readmissions Following Degenerative Posterior Cervical Spine Surgery Utilizing the Nationwide Readmissions Database by Rumalla, Kavelin, Smith, Kyle A, Arnold, Paul M

“…Abstract BACKGROUND Hospital readmissions have profound financial and clinical impacts. Analyses of 30-day readmissions following spine surgery have been…”
Get full text

Cervical Total Disc Replacement and Anterior Cervical Discectomy and Fusion: Reoperation Rates, Complications, and Hospital Resource Utilization in 72 688 Patients in the United States by Rumalla, Kavelin, Smith, Kyle A, Arnold, Paul M

“…Abstract BACKGROUND Healthcare readmissions are important causes of increased cost and have profound clinical impact. Thirty-day readmissions in spine surgery…”
Get full text

Exercise and adrenergic regulation of immunity by Simpson, Richard J., Boßlau, Tim K., Weyh, Christopher, Niemiro, Grace M., Batatinha, Helena, Smith, Kyle A., Krüger, Karsten

“…[Display omitted] •Exercise positively impacts immunity to help prevent or ameliorate many diseases.•Exercise activates adrenergic signaling pathways to…”
Get full text

Hydrocephalus in Pediatric Traumatic Brain Injury: National Incidence, Risk Factors, and Outcomes in 124,444 Hospitalized Patients by Rumalla, Kavelin, Letchuman, Vijay, Smith, Kyle A., Arnold, Paul M.

“…Hydrocephalus is a life-threatening sequela of traumatic brain injury (TBI) with poorly defined epidemiology in children. Here, we report the national…”
Get full text

Subarachnoid Hemorrhage and Readmissions: National Rates, Causes, Risk Factors, and Outcomes in 16,001 Hospitalized Patients by Rumalla, Kavelin, Smith, Kyle A., Arnold, Paul M., Mittal, Manoj K.

“…The acute complications of aneurysmal subarachnoid hemorrhage (aSAH) often lead to readmissions, which are linked to hospital reimbursement. The national…”
Get full text

Gastrointestinal pathophysiology during endurance exercise: endocrine, microbiome, and nutritional influences by Smith, Kyle A., Pugh, Jamie N., Duca, Frank A., Close, Graeme L., Ormsbee, Michael J.

“…Gastrointestinal symptoms are abundant among athletes engaging in endurance exercise, particularly when exercising in increased environmental temperatures, at…”
Get full text

Neuroendoscopic fenestration of glioependymal cysts to the ventricle: report of 3 cases by Alvarado, Anthony M, Smith, Kyle A, Chamoun, Roukoz B

“…Glioependymal cysts are rare congenital lesions of the central nervous system. Reported surgical treatments of these lesions have varied and yielded mixed…”
Get full text

Scientific, Clinical, Regulatory, and Economic Aspects of Choosing Bone Graft/Biological Options in Spine Surgery by Smith, Kyle A, Russo, Glenn S, Vaccaro, Alexander R, Arnold, Paul M

“…Abstract Spinal arthrodesis is a major element of the spinal surgeon's practice. To attain successful fusion rates, attention must be paid to spinal segment…”
Get full text

Recent COVID-19 vaccination has minimal effects on the physiological responses to graded exercise in physically active healthy people by Batatinha, Helena, Baker, Forrest L, Smith, Kyle A, Zúñiga, Tiffany M, Pedlar, Charles R, Burgess, Shane C, Katsanis, Emmanuel, Simpson, Richard J

“…Athletes are advised to receive the COVID-19 vaccination to protect themselves from SARS-CoV-2 infection during major competitions. Despite this, many athletes…”
Get full text

Immunoglobulin G4-related epidural inflammatory pseudotumor presenting with pulmonary complications and spinal cord compression: case report by Rumalla, Kavelin, Smith, Kyle A, Arnold, Paul M

“…Immunoglobulin G4-related disease (IgG4-RD) is a recently defined condition characterized by inflammatory tumefactive lesions in various organ systems. IgG4-RD…”
Get full text

Clonal Kinetics and Single-Cell Transcriptional Profiles of T Cells Mobilized to Blood by Acute Exercise by ZÚÑIGA, TIFFANY M., BAKER, FORREST L., SMITH, KYLE A., BATATINHA, HELENA, LAU, BRANDEN, BURGESS, SHANE C., GUSTAFSON, MICHAEL P., KATSANIS, EMMANUEL, SIMPSON, RICHARD J.

“…Acute exercise redistributes large numbers of memory T cells, which may contribute to enhanced immune surveillance in regular exercisers. It is not known,…”
Get full text

Nationwide incidence and risk factors for posttraumatic seizures in children with traumatic brain injury by Rumalla, Kavelin, Smith, Kyle A, Letchuman, Vijay, Gandham, Mrudula, Kombathula, Rachana, Arnold, Paul M

“…OBJECTIVEPosttraumatic seizures (PTSs) are the most common complication following a traumatic brain injury (TBI) and may lead to posttraumatic epilepsy. PTS is…”
Get full text