Search Results - "Smith, Kayla J."

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  1. 1

    Editor's Highlight: Ah Receptor Activation Potentiates Neutrophil Chemoattractant (C-X-C Motif) Ligand 5 Expression in Keratinocytes and Skin by Smith, Kayla J, Boyer, Jacob A, Muku, Gulsum E, Murray, Iain A, Gowda, Krishne, Desai, Dhimant, Amin, Shantu G, Glick, Adam B, Perdew, Gary H

    Published in Toxicological sciences (01-11-2017)
    “…Chemokines are components of the skin microenvironment, which enable immune cell chemotaxis. Traditionally, transcription factors involved in inflammatory…”
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    Journal Article
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    Allelic variants of the aryl hydrocarbon receptor differentially influence UVB-mediated skin inflammatory responses in SKH1 mice by Smith, Kayla J., Murray, Iain A., Boyer, Jacob A., Perdew, Gary H.

    Published in Toxicology (Amsterdam) (01-02-2018)
    “…•Outcrossed SKH1 mice contain several alleles of the Ahr.•SKH1 mice were backcrossed with C57BL6/J mice to obtain the Ahb−1 allele.•SKH1 mouse lines with…”
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    Journal Article
  5. 5

    Identification of a high-affinity ligand that exhibits complete aryl hydrocarbon receptor antagonism by Smith, Kayla J, Murray, Iain A, Tanos, Rachel, Tellew, John, Boitano, Anthony E, Bisson, William H, Kolluri, Siva K, Cooke, Michael P, Perdew, Gary H

    “…The biological functions of the aryl hydrocarbon receptor (AHR) can be delineated into dioxin response element (DRE)-dependent or -independent activities…”
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    Journal Article
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    Ligand-mediated cytoplasmic retention of the Ah receptor inhibits macrophage-mediated acute inflammatory responses by Muku, Gulsum E, Lahoti, Tejas S, Murray, Iain A, Podolsky, Michael A, Smith, Kayla J, Hubbard, Troy D, Kuzu, Guray, Gowda, Krishne, Amin, Shantu G, Perdew, Gary H

    Published in Laboratory investigation (01-12-2017)
    “…The Ah receptor (AHR) has been shown to exhibit both inflammatory and anti-inflammatory activity in a context-specific manner. In vivo macrophage-driven acute…”
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    Journal Article
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    The Role of the Aryl Hydrocarbon Receptor in Modulating Skin and Intestinal Epithelial Physiology by Smith, Kayla J

    Published 01-01-2017
    “…Barrier tissues such as the skin and intestine are important for the first line of defense against injury and exposure to potentially harmful toxicants or…”
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    Dissertation