Search Results - "Smith, Kathleen J."
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Eruptive Keratoacanthoma‐Type Squamous Cell Carcinomas in Patients Taking Sorafenib for the Treatment of Solid Tumors
Published in Dermatologic surgery (01-11-2009)“…BACKGROUND Protein kinases (PKs) are indispensable for most cellular processes, and deregulation of PKs can lead to activation of oncogenic and anti‐apoptotic…”
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Nuclear expression of the antiapoptotic protein survivin in malignant melanoma
Published in Cancer (01-03-2006)“…BACKGROUND Expression of the antiapoptotic protein survivin has been demonstrated in some melanocytic lesions and is believed to be required for melanoma cell…”
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Polycystic ovary syndrome (PCOS) with melanocytic mucosal macules: the role of STK11 gene polymorphisms in PCOS and Peutz-Jeghers syndrome
Published in International journal of dermatology (01-02-2016)“…Background Polycystic ovary syndrome (PCOS) is a complex genetic disorder that is the most common endocrinopathy that affects women. Observations We report two…”
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Lichen planus associated with hepatitis C virus: no viral transcripts are found in the lichen planus, and effective therapy for hepatitis C virus does not clear lichen planus
Published in Journal of the American Academy of Dermatology (01-11-2003)“…Although hepatitis C virus (HCV) was not discovered until 1989, it was recognized for many years that a viral agent was responsible for many cases of…”
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Should hyaluronic acid fillers be diluted?
Published in Journal of drugs in dermatology (01-12-2014)Get more information
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Leflunomide: an immune modulating drug that may have a role in controlling secondary infections with review of its mechanisms of action
Published in Journal of drugs in dermatology (01-03-2015)“…Leflunomide (LEF) is an immune modulator used most commonly for rheumatoid arthritis (RA). The mechanisms of action of LEF also include anti-microbial effects,…”
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Histologic features in primary cutaneous squamous cell carcinomas in immunocompromised patients focusing on organ transplant patients
Published in Dermatologic surgery (01-04-2004)“…In organ transplant recipients (OTR) there is an increased incidence of cutaneous squamous cell carcinomas (CSCC), and they may be aggressive. We wanted to…”
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Chemical warfare agents: their past and continuing threat and evolving therapies. Part I of II
Published in Skinmed (01-07-2003)“…Chemical warfare agents are potentially accessible to even underdeveloped nations because they are easily and inexpensively produced. This means that they are…”
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Rapid onset of cutaneous squamous cell carcinoma in patients with rheumatoid arthritis after starting tumor necrosis factor α receptor IgG1-Fc fusion complex therapy
Published in Journal of the American Academy of Dermatology (01-12-2001)“…Tumor necrosis factor α (TNF-α) is now believed to be a major contributor to the pathogenesis of the synovitis and joint destruction in rheumatoid arthritis…”
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Molluscum contagiosum: recent advances in pathogenic mechanisms, and new therapies
Published in American journal of clinical dermatology (2002)“…Two poxviruses, Molluscum contagiosum virus (MCV) and Variola virus are specific to humans. MCV is present worldwide and is directly passed by direct skin to…”
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Squamous Cell Carcinoma in Situ (Bowen's Disease) in Renal Transplant Patients Treated with 5% Imiquimod and 5% 5‐Fluorouracil Therapy
Published in Dermatologic surgery (01-06-2001)“…Background. Depending upon the patient's age at transplant, skin type, sun exposure, and the need for immunosuppressive therapy to prevent rejection, there is…”
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Topical 5% imiquimod for the therapy of actinic cheilitis
Published in Journal of the American Academy of Dermatology (01-10-2002)“…Background: Tissue-destructive and more selective cytotoxic therapies are the main methods used to treat actinic cheilitis. A topical immune stimulant, 5%…”
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Microcystic adnexal carcinoma: An immunohistochemical study including markers of proliferation and apoptosis
Published in The American journal of surgical pathology (01-04-2001)“…Microcystic adnexal carcinoma (MAC) is the prototype for a subset of locally aggressive adnexal carcinomas (LAACs). Ultraviolet radiation (UVR) and UVB…”
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Basaloid follicular hamartomas associated with autoimmune disease: a possible role for retinoids in therapy
Published in Journal of the American Academy of Dermatology (01-12-2003)“…A basaloid follicular hamartoma (BFH) may be localized or diffuse. It may also be congenital or acquired. Development of diffuse BFHs has been associated with…”
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Bowen's Disease (Squamous Cell Carcinoma In Situ) in Immunosuppressed Patients Treated with Imiquimod 5% Cream and a COX Inhibitor, Sulindac: Potential Applications for This Combination of Immunotherapy
Published in Dermatologic surgery (01-02-2001)“…Background. Patients with chronic lymphocytic leukemia (CLL) often have a protracted course. However, all these patients are immunosuppressed and may have a…”
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Hair follicle nevus in a distribution following Blaskho's lines
Published in Journal of the American Academy of Dermatology (01-05-2002)“…We present a case of a rare follicular hamartoma, a hair follicle nevus. Although most previous reports have been solitary lesions, the case we are reporting…”
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Histopathologic features seen with radiation recall or enhancement eruptions
Published in Journal of cutaneous medicine and surgery (01-11-2002)“…Although a radiation recall or enhancement eruption has been associated with a number of chemotherapeutic drugs, the histologic features have rarely been…”
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Dermatofibrosarcoma protuberans and giant cell fibroblastoma exhibit CD99 positivity
Published in Journal of cutaneous pathology (01-07-2008)“…According to most authors, dermatofibrosarcoma protuberans (DFSP) and giant cell fibroblastoma (GCF) represent the adult and juvenile forms, respectively, of…”
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