Search Results - "Smith, Joseph D"

EPCR and Malaria Severity: The Center of a Perfect Storm by Bernabeu, Maria, Smith, Joseph D

“…Severe malaria due to Plasmodium falciparum infection causes nearly half a million deaths per year. The different symptomatology and disease manifestations…”
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The role of PfEMP1 adhesion domain classification in Plasmodium falciparum pathogenesis research by Smith, Joseph D.

“…•The PfEMP1 protein family is a major virulence determinant for P. falciparum.•PfEMP1 size and sequence polymorphism obscures binding patterns.•Domain…”
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Thermal Decomposition and Kinetic Parameters of Three Biomass Feedstocks for the Performance of the Gasification Process Using a Thermogravimetric Analyzer by Almusafir, Rania, Smith, Joseph D.

“…Thermogravimetric analysis (TGA) is a powerful technique and useful method for characterizing biomass as a non-conventional fuel. A TGA apparatus has been…”
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Interaction between Endothelial Protein C Receptor and Intercellular Adhesion Molecule 1 to Mediate Binding of Plasmodium falciparum-Infected Erythrocytes to Endothelial Cells by Avril, Marion, Bernabeu, Maria, Benjamin, Maxwell, Brazier, Andrew Jay, Smith, Joseph D

“…Intercellular adhesion molecule 1 (ICAM-1) and the endothelial protein C receptor (EPCR) are candidate receptors for the deadly complication cerebral malaria…”
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Investigating the Pathogenesis of Severe Malaria: A Multidisciplinary and Cross-Geographical Approach by Wassmer, Samuel C, Taylor, Terrie E, Rathod, Pradipsinh K, Mishra, Saroj K, Mohanty, Sanjib, Arevalo-Herrera, Myriam, Duraisingh, Manoj T, Smith, Joseph D

“…More than a century after the discovery of Plasmodium spp. parasites, the pathogenesis of severe malaria is still not well understood. The majority of malaria…”
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Probing cerebral malaria inflammation in 3D human brain microvessels by Howard, Caitlin, Joof, Fatou, Hu, Ruoqian, Smith, Joseph D., Zheng, Ying

“…Sequestration of Plasmodium falciparum-infected erythrocytes (IEs) in the brain microcirculation is a hallmark of cerebral malaria (CM), which leads to…”
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Teaching Energy Economics in the GCC: A Synergistic Approach between Engineering and Economics by Zhou, Yishu, Smith, Joseph D., Gelles, Greg

“…Issues related to safe and abundant energy production have been prominent in recent years. This is particularly true when society considers how to increase the…”
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restricted subset of var genes mediates adherence of Plasmodium falciparum-infected erythrocytes to brain endothelial cells by Avril, Marion, Tripathi, Abhai K, Brazier, Andrew J, Andisi, Cheryl, Janes, Joel H, Soma, Vijaya L, Sullivan, David J, Bull, Peter C, Stins, Monique F, Smith, Joseph D

“…Cerebral malaria (CM) is a deadly complication of Plasmodium falciparum infection, but specific interactions involved in cerebral homing of infected…”
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DC8 and DC13 var genes associated with severe malaria bind avidly to diverse endothelial cells by Avril, Marion, Brazier, Andrew J, Melcher, Martin, Sampath, Sowmya, Smith, Joseph D

“…During blood stage infection, Plasmodium falciparum infected erythrocytes (IE) bind to host blood vessels. This virulence determinant enables parasites to…”
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Binding Heterogeneity of Plasmodium falciparum to Engineered 3D Brain Microvessels Is Mediated by EPCR and ICAM-1 by Bernabeu, Maria, Gunnarsson, Celina, Vishnyakova, Maria, Howard, Caitlin C, Nagao, Ryan J, Avril, Marion, Taylor, Terrie E, Seydel, Karl B, Zheng, Ying, Smith, Joseph D

“…Cerebral malaria is a severe neurological complication associated with sequestration of -infected erythrocytes (IE) in the brain microvasculature, but the…”
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Investigating the host binding signature on the Plasmodium falciparum PfEMP1 protein family by Janes, Joel H, Wang, Christopher P, Levin-Edens, Emily, Vigan-Womas, Inès, Guillotte, Micheline, Melcher, Martin, Mercereau-Puijalon, Odile, Smith, Joseph D

“…The Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) family plays a central role in antigenic variation and cytoadhesion of P. falciparum infected…”
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Biophysical and biomolecular interactions of malaria-infected erythrocytes in engineered human capillaries by Arakawa, Christopher, Gunnarsson, Celina, Howard, Caitlin, Bernabeu, Maria, Phong, Kiet, Yang, Eric, DeForest, Cole A, Smith, Joseph D, Zheng, Ying

“…Microcirculatory obstruction is a hallmark of severe malaria, but mechanisms of parasite sequestration are only partially understood. Here, we developed a…”
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Advances in Energy Hybridization for Resilient Supply: A Sustainable Approach to the Growing World Demand by Al-Rubaye, Haider, Smith, Joseph D., Zangana, Mohammed H. S., Nagapurkar, Prashant, Zhou, Yishu, Gelles, Greg

“…Energy poverty, defined as a lack of access to reliable electricity and reliance on traditional biomass resources for cooking, affects over a billion people…”
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Plasmodium falciparum Parasite Lines Expressing DC8 and Group A PfEMP1 Bind to Brain, Intestinal, and Kidney Endothelial Cells by Ortolan, Luana S, Avril, Marion, Xue, Jun, Seydel, Karl B, Zheng, Ying, Smith, Joseph D

“…Cytoadhesion of -infected red blood cells is a virulence determinant associated with microvascular obstruction and organ complications. The gastrointestinal…”
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Design and simulation of a utility oilfield flare in Iraq/Kurdistan region using CFD and API-521 methodology by Maaroof, Ahmed A., Smith, Joseph D., Zangana, Mohammed H.S.

“…This paper aims at reviewing and analyzing the operation and design of a utility flare in an oilfield in the Iraq/Kurdistan region. The flare supports a gas…”
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Techno-economic optimization and environmental Life Cycle Assessment (LCA) of microgrids located in the US using genetic algorithm by Nagapurkar, Prashant, Smith, Joseph D.

“…•Techno-economic optimization and environmental analysis (LCA) of microgrid was performed.•Found optimum microgrid configuration with lowest LCOE ($/kWh) using…”
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High avidity antibodies to full-length VAR2CSA correlate with absence of placental malaria by Tutterrow, Yeung Lo, Salanti, Ali, Avril, Marion, Smith, Joseph D, Pagano, Ian S, Ako, Simon, Fogako, Josephine, Leke, Rose G F, Taylor, Diane Wallace

“…VAR2CSA mediates sequestration of Plasmodium falciparum-infected erythrocytes in the placenta, increasing the risk of poor pregnancy outcomes. Naturally…”
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High Levels of Antibodies to Multiple Domains and Strains of VAR2CSA Correlate with the Absence of Placental Malaria in Cameroonian Women Living in an Area of High Plasmodium falciparum Transmission by TUTTERROW, Yeung L, AVRIL, Marion, SINGH, Kavita, LONG, Carole A, LEKE, Robert J, SAMA, Grace, SALANTI, Ali, SMITH, Joseph D, LEKE, Rose G. F, TAYLOR, Diane W

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Patterns of gene recombination shape var gene repertoires in Plasmodium falciparum: comparisons of geographically diverse isolates by Kraemer, Susan M, Kyes, Sue A, Aggarwal, Gautam, Springer, Amy L, Nelson, Siri O, Christodoulou, Zoe, Smith, Leia M, Wang, Wendy, Levin, Emily, Newbold, Christopher I, Myler, Peter J, Smith, Joseph D

“…Var genes encode a family of virulence factors known as PfEMP1 (Plasmodium falciparum erythrocyte membrane protein 1) which are responsible for both antigenic…”
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Evidence for the importance of genetic structuring to the structural and functional specialization of the Plasmodium falciparum var gene family by Kraemer, Susan M., Smith, Joseph D.

“…Summary The var gene family encodes Plasmodium falciparum erythrocyte membrane 1 (PfEMP1) proteins that act as virulence factors responsible for both antigenic…”
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