Search Results - "Smith, John W"

Overall survival with neratinib after trastuzumab-based adjuvant therapy in HER2-positive breast cancer (ExteNET): A randomised, double-blind, placebo-controlled, phase 3 trial by Holmes, Frankie A., Moy, Beverly, Delaloge, Suzette, Chia, Stephen K.L., Ejlertsen, Bent, Mansi, Janine, Iwata, Hiroji, Gnant, Michael, Buyse, Marc, Barrios, Carlos H., Silovski, Tajana, Šeparović, Robert, Bashford, Anna, Zotano, Angel Guerrero, Denduluri, Neelima, Patt, Debra, Gokmen, Erhan, Gore, Ira, Smith, John W., Loibl, Sibylle, Masuda, Norikazu, Tomašević, Zorica, Petráková, Katarina, DiPrimeo, Daniel, Wong, Alvin, Martin, Miguel, Chan, Arlene

“…ExteNET showed that neratinib, an irreversible pan-HER tyrosine kinase inhibitor, given for 1 year after trastuzumab-based therapy significantly improved…”
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Polymerization-Like Co-Assembly of Silver Nanoplates and Patchy Spheres by Luo, Binbin, Smith, John W, Wu, Zixuan, Kim, Juyeong, Ou, Zihao, Chen, Qian

“…Highly anisometric nanoparticles have distinctive mechanical, electrical, and thermal properties and are therefore appealing candidates for use as…”
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Hierarchical self-assembly of 3D lattices from polydisperse anisometric colloids by Luo, Binbin, Kim, Ahyoung, Smith, John W., Ou, Zihao, Wu, Zixuan, Kim, Juyeong, Chen, Qian

“…Colloids are mainly divided into two types defined by size. Micron-scale colloids are widely used as model systems to study phase transitions, while…”
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Beyond nothingness in the formation and functional relevance of voids in polymer films by Kalutantirige, Falon C., He, Jinlong, Yao, Lehan, Cotty, Stephen, Zhou, Shan, Smith, John W., Tajkhorshid, Emad, Schroeder, Charles M., Moore, Jeffrey S., An, Hyosung, Su, Xiao, Li, Ying, Chen, Qian

“…Voids—the nothingness—broadly exist within nanomaterials and impact properties ranging from catalysis to mechanical response. However, understanding nanovoids…”
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Linked within-host and between-host models and data for infectious diseases: a systematic review by Childs, Lauren M, El Moustaid, Fadoua, Gajewski, Zachary, Kadelka, Sarah, Nikin-Beers, Ryan, Smith, Jr, John W, Walker, Melody, Johnson, Leah R

“…The observed dynamics of infectious diseases are driven by processes across multiple scales. Here we focus on two: within-host, that is, how an infection…”
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Charge Separation in the Aerodynamic Breakup of Micrometer-Sized Water Droplets by Zilch, Lloyd W, Maze, Joshua T, Smith, John W, Ewing, George E, Jarrold, Martin F

“…Charged water droplets generated by electrospray, sonic spray, and a vibrating orifice aerosol generator (VOAG) have been studied by digital macrophotography…”
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Durable responses and reversible toxicity of high-dose interleukin-2 treatment of melanoma and renal cancer in a Community Hospital Biotherapy Program by Payne, Roxanne, Glenn, Lyn, Hoen, Helena, Richards, Beverley, Smith, 2nd, John W, Lufkin, Robert, Crocenzi, Todd S, Urba, Walter J, Curti, Brendan D

“…High-dose interleukin-2 (IL-2) has been FDA-approved for over 20 years, but it is offered only at a small number of centers with expertise in its…”
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Circulating tumor cell number and endocrine therapy index in ER positive metastatic breast cancer patients by Paoletti, Costanza, Regan, Meredith M., Niman, Samuel M., Dolce, Emily M., Darga, Elizabeth P., Liu, Minetta C., Marcom, P. Kelly, Hart, Lowell L., Smith, John W., Tedesco, Karen L., Amir, Eitan, Krop, Ian E., DeMichele, Angela M., Goodwin, Pamela J., Block, Margaret, Aung, Kimberly, Brown, Martha E., McCormack, Robert T., Hayes, Daniel F.

“…Circulating tumor cells (CTC) are prognostic in metastatic breast cancer (MBC). The CTC-endocrine therapy index (CTC-ETI), consisting of CTC-ER (estrogen…”
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Sunitinib Plus Paclitaxel Versus Bevacizumab Plus Paclitaxel for First-Line Treatment of Patients With Advanced Breast Cancer: A Phase III, Randomized, Open-Label Trial by Robert, Nicholas J, Saleh, Mansoor N, Paul, Devchand, Generali, Daniele, Gressot, Laurent, Copur, Mehmet S, Brufsky, Adam M, Minton, Susan E, Giguere, Jeffrey K, Smith, John W, Richards, Paul D, Gernhardt, Diana, Huang, Xin, Liau, Katherine F, Kern, Kenneth A, Davis, John

“…Abstract Introduction A multicenter, open-label phase III study was conducted to test whether sunitinib plus paclitaxel prolongs progression-free survival…”
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Quantifying the Self-Assembly Behavior of Anisotropic Nanoparticles Using Liquid-Phase Transmission Electron Microscopy by Luo, Binbin, Smith, John W, Ou, Zihao, Chen, Qian

“…For decades, one of the overarching objectives of self-assembly science has been to define the rules necessary to build functional, artificial materials with…”
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Adjuvant High-Dose Bolus Interleukin-2 for Patients With High-Risk Renal Cell Carcinoma: A Cytokine Working Group Randomized Trial by CLARK, Joseph I, ATKINS, Michael B, WEISS, Geoffrey R, REDMAN, Bruce G, TRETTER, Christopher P. G, MCDERMOTT, David, SMITH, John W, GORDON, Michael S, MARGOLIN, Kim A, URBA, Walter J, CREECH, Steven, FIGLIN, Robert A, DUTCHER, Janice P, FLAHERTY, Larry, SOSMAN, Jeffrey A, LOGAN, Theodore F, WHITE, Richard

“…This prospective, randomized, controlled phase III trial assessed high-dose bolus interleukin-2 (IL-2) postoperatively in patients with high-risk renal cell…”
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Phase II randomized trial of weekly and every-3-week ixabepilone in metastatic breast cancer patients by Smith, John W., Vukelja, Svetislava, Rabe, Amy, Wentworth-Hartung, Nicole, Koutrelakos, Nicholas, Shao, Spencer H., Whittaker, Thomas, Wang, Yunfei, Asmar, Lina, McDowell, Diane Opatt, Mukhopadhyay, Pralay, O’Shaughnessy, Joyce

“…This multicenter, open-label, randomized phase II trial compared the efficacy and tolerability of weekly ixabepilone versus the standard 3 weekly dosing…”
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Results of a phase II open-label, nonrandomized trial of oral satraplatin in patients with metastatic breast cancer by Smith, John W. II, McIntyre, Kristi J, Acevedo, Patrick V, Encarnacion, Carlos A, Tedesco, Karen L, Wang, Yunfei, Asmar, Lina, O'Shaughnessy, Joyce A

“…Cisplatin and carboplatin have antitumor activity in breast cancer. Satraplatin, an orally bioavailable platinum analog, offers a potential alternative to…”
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Phase II, Multicenter, Single-Arm, Feasibility Study of Eribulin Combined With Capecitabine for Adjuvant Treatment in Estrogen Receptor-Positive, Early-Stage Breast Cancer by Smith, John W, Vukelja, Svetislava, Hoffman, Anthony D, Jones, Vicky E, McIntyre, Kristi, Berrak, Erhan, Song, James X, O'Shaughnessy, Joyce

“…Micro-Abstract Eribulin plus capecitabine as adjuvant therapy was feasible in postmenopausal women with early-stage, human epidermal growth factor receptor…”
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Phase I Trial of BAY 50-4798, an Interleukin-2–Specific Agonist in Advanced Melanoma and Renal Cancer by Margolin, Kim, Atkins, Michael B, Dutcher, Janice P, Ernstoff, Marc S, Smith, 2nd, John W, Clark, Joseph I, Baar, Joseph, Sosman, Jeffrey, Weber, Jeffrey, Lathia, Chetan, Brunetti, Janice, Cihon, Frank, Schwartz, Brian

“…Purpose: BAY 50-4798 is an analogue of interleukin-2 that selectively activates T cells over natural killer cells. This phase I study was designed to determine…”
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Granulocyte-macrophage colony-stimulating factor gene-modified autologous tumor vaccines in non-small-cell lung cancer by NEMUNAITIS, John, STERNUM, Daniel, HEGE, Kristen, JABLONS, David, SMITH, John W, FOX, Bernard, MAPLES, Phil, HAMILTON, Scott, BORELLINI, Flavia, LIN, Andy, MORALI, Sayeh

“…To evaluate the feasibility, safety, and efficacy of vaccination with autologous tumor cells genetically modified with an adenoviral vector (Ad-GM) to secrete…”
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Pulsed Acceleration Charge Detection Mass Spectrometry:  Application to Weighing Electrosprayed Droplets by Mabbett, Sarah R, Zilch, Lloyd W, Maze, Joshua T, Smith, John W, Jarrold, Martin F

“…We describe a new approach to measuring the masses of individual macroions. The method employs a pulsed acceleration tube located between two sensitive image…”
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Adjuvant Immunization of HLA-A2–Positive Melanoma Patients With a Modified gp100 Peptide Induces Peptide-Specific CD8+ T-Cell Responses by SMITH, John W, WALKER, Edwin B, MAECKER, Holden, DOLS, Annemiek, MEIJER, Sybren, HU, Hong-Ming, ROMERO, Pedro, ALVORD, W. Gregory, URBA, Walter J, FOX, Bernard A, HALEY, Daniel, WISNER, Ketura P, DORAN, Teri, FISHER, Brenda, JUSTICE, Lisa, WOOD, William, VETTO, John

“…To measure the CD8+ T-cell response to a melanoma peptide vaccine and to compare an every-2-weeks with an every-3-weeks vaccination schedule. Thirty…”
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Targeting FGFR with Dovitinib (TKI258): Preclinical and Clinical Data in Breast Cancer by ANDRE, Fabrice, BACHELOT, Thomas, SHI, Michael, YONG ZHANG, KAY, Andrea, GRAUS PORTA, Diana, YOVINE, Alejandro, BASELGA, José, CAMPONE, Mario, DALENC, Florence, PEREZ-GARCIA, Jose M, HURVITZ, Sara A, TURNER, Nicholas, RUGO, Hope, SMITH, John W, DEUDON, Stephanie

“…Fibroblast growth factor receptor 1 (FGFR1) and FGFR2 amplifications are observed in approximately 10% of breast cancers and are related to poor outcomes. We…”
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Reconfigurable Polymer Shells on Shape‐Anisotropic Gold Nanoparticle Cores by Kim, Juyeong, Song, Xiaohui, Kim, Ahyoung, Luo, Binbin, Smith, John W., Ou, Zihao, Wu, Zixuan, Chen, Qian

“…Reconfigurable hybrid nanoparticles made by decorating flexible polymer shells on rigid inorganic nanoparticle cores can provide a unique means to build…”
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