Search Results - "Smith, Johanna"
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Human vaginal fluid contains exosomes that have an inhibitory effect on an early step of the HIV-1 life cycle
Published in AIDS (London) (13-11-2016)“…OBJECTIVE:Vaginal transmission is crucial to the spread of HIV-1 around the world. It is not yet clear what type (s) of innate defenses against HIV-1 infection…”
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Genome-wide association and genotype by environment interactions for growth traits in U.S. Red Angus cattle
Published in BMC genomics (16-07-2022)“…Abstract Background Genotypic information produced from single nucleotide polymorphism (SNP) arrays has routinely been used to identify genomic regions…”
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Genome-wide association and genotype by environment interactions for growth traits in U.S. Gelbvieh cattle
Published in BMC genomics (04-12-2019)“…Single nucleotide polymorphism (SNP) arrays have facilitated discovery of genetic markers associated with complex traits in domestic cattle; thereby enabling…”
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Finding the right words: Articulating the value of mental health promotion. A focus group study
Published in Journal of community psychology (01-09-2022)“…The Lapinlahti Hospital initiative in Helsinki has transformed a disused psychiatric hospital into an open site for mental health promotion. The current study…”
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Implementing Reporting Standards for Polygenic Risk Scores for Atherosclerotic Cardiovascular Disease
Published in Current atherosclerosis reports (01-06-2023)“…Purpose of Review There is considerable interest in using polygenic risk scores (PRSs) for assessing risk of atherosclerotic cardiovascular disease (ASCVD). A…”
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Clumped isotope evidence for diachronous surface cooling of the Altiplano and pulsed surface uplift of the Central Andes
Published in Earth and planetary science letters (01-05-2014)“…Spatially extensive paleoelevation records of the Altiplano plateau are critical to determining the geodynamic mechanisms that formed and support high…”
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Surveying the Landscape: A Review of Longitudinal Traumatic Brain Injury Studies in Service Member and Veteran Populations
Published in Journal of neurotrauma (01-06-2023)“…Traumatic brain injury (TBI) is known to be a signature wound of the post-9/11 conflicts. In response, the U.S. Department of Defense (DOD) and other federal…”
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Selection, optimization and validation of ten chronic disease polygenic risk scores for clinical implementation in diverse US populations
Published in Nature medicine (01-02-2024)“…Polygenic risk scores (PRSs) have improved in predictive performance, but several challenges remain to be addressed before PRSs can be implemented in the…”
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Cross-Walk Comparison of the DVBIC-TBICoE and LIMBIC-CENC Combat-Related Concussion Prospective Longitudinal Study Datasets
Published in Archives of physical medicine and rehabilitation (01-07-2023)“…To describe and compare cohorts between 2 large, longitudinal, federally-funded TBI studies of Service members and veterans across demographic, self-report,…”
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‘If we would change things outside we wouldn’t even need to go in…’ supporting recovery via community‐based actions: A focus group study on psychiatric rehospitalization
Published in Health expectations : an international journal of public participation in health care and health policy (01-05-2021)“…Background Psychiatric rehospitalization is a complex phenomenon in need of more person‐centred approaches. The current paper aimed to explore how…”
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HIV-1 Tat and AIDS-associated cancer: targeting the cellular anti-cancer barrier?
Published in Journal of experimental & clinical cancer research (15-05-2008)“…The acquired immunodeficiency syndrome (AIDS) is accompanied by a significant increase in the incidence of neoplasms. Several causative agents have been…”
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Parent-delivered interventions used at home to improve eating, drinking and swallowing in children with neurodisability: the FEEDS mixed-methods study
Published in Health technology assessment (Winchester, England) (01-03-2021)“…Eating, drinking and swallowing difficulties are common in young children with neurodisability. These difficulties may lead to inadequate calorie intake, which…”
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Outcome assessment of a complex mental health intervention in the workplace. Results from the MENTUPP pilot study
Published in International archives of occupational and environmental health (01-10-2023)“…Objective Multicomponent interventions are recommendable to achieve the greatest mental health benefits, but are difficult to evaluate due to their complexity…”
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Interventions to mitigate the effects of poverty and inequality on mental health
Published in Social Psychiatry and Psychiatric Epidemiology (01-05-2017)“…Purpose To review psychosocial and policy interventions which mitigate the effects of poverty and inequality on mental health. Methods Systematic reviews,…”
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Integration site selection by retroviral vectors: molecular mechanism and clinical consequences
Published in Human gene therapy (01-06-2008)“…Retroviral DNA integration into the host cell genome is an essential feature of the retroviral life cycle. The ability to integrate their DNA into the DNA of…”
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Standing frames for children with cerebral palsy: a mixed-methods feasibility study
Published in Health technology assessment (Winchester, England) (01-09-2018)“…Standing frames are recommended as part of postural management for young people with cerebral palsy (CP) Gross Motor Function Classification System (GMFCS)…”
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Pyruvate kinase expression (PKM1 and PKM2) in cancer-associated fibroblasts drives stromal nutrient production and tumor growth
Published in Cancer biology & therapy (15-12-2011)“…We have previously demonstrated that enhanced aerobic glycolysis and/or autophagy in the tumor stroma supports epithelial cancer cell growth and aggressive…”
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Modification of integration site preferences of an HIV-1-based vector by expression of a novel synthetic protein
Published in Human gene therapy (01-03-2010)“…HIV-1-based lentiviral vectors are a promising tool for gene therapy. However, integration of a lentiviral vector into host cell genes may lead to the…”
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Stem cells and aging: a chicken-or-the-egg issue?
Published in Aging and disease (01-06-2012)“…Aging is a process that involves all organs and tissues of the human organism. Cells and tissues are impacted by aging in differing degrees, depending on their…”
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Genome-wide association and genomic prediction for a reproductive index summarizing fertility outcomes in U.S. Holsteins
Published in G3 : genes - genomes - genetics (01-09-2023)“…Abstract Subfertility represents one major challenge to enhancing dairy production and efficiency. Herein, we use a reproductive index (RI) expressing the…”
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