Search Results - "Smith, James W"

The sensitivity and specificity of platelet autoantibody testing in immune thrombocytopenia: a systematic review and meta‐analysis of a diagnostic test by Vrbensky, John R., Moore, Joyce E., Arnold, Donald M., Smith, James W., Kelton, John G., Nazy, Ishac

“…Essentials The diagnosis of ITP is based on a platelet count < 100 × 109 L−1 and exclusion of other causes. There are no standard tests or biomarkers to…”
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Approach to the Diagnosis and Management of Drug-Induced Immune Thrombocytopenia by Arnold, Donald M, Nazi, Ishac, Warkentin, Theodore E, Smith, James W, Toltl, Lisa J, George, James N, Kelton, John G

“…Abstract Drug-induced immune thrombocytopenia (DITP) is a challenging clinical problem that is under-recognized, difficult to diagnose and associated with…”
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Characteristics and Practices of Highly Rated Senior Leadership Teams: A Comparative Case Study of CCCU Institutions by Smith, James W., Monihen, Lindsay K.

“…The purpose of this comparative case study research project was to identify the characteristics and practices utilized by the senior leadership teams (SLTs) at…”
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Megakaryocyte apoptosis in immune thrombocytopenia by Vrbensky, John R., Nazy, Ishac, Toltl, Lisa J., Ross, Catherine, Ivetic, Nikola, Smith, James W., Kelton, John G., Arnold, Donald M.

“…The mechanisms of platelet underproduction in immune thrombocytopenia (ITP) remain unknown. While the number of megakaryocytes is normal or increased in ITP…”
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Amino acid imbalance with excess methionine in late-finishing pigs: effects on performance and carcass quality by Edmonds, Michael S, Smith, James W

“…Limitations in harvest facility capacity can necessitate feeding strategies to slow growth rate in late-finishing pigs. In Experiment 1, six dietary treatments…”
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Characteristics of Anti-SARS-CoV-2 Antibodies in Recovered COVID-19 Subjects by Huynh, Angela, Arnold, Donald M, Smith, James W, Moore, Jane C, Zhang, Ali, Chagla, Zain, Harvey, Bart J, Stacey, Hannah D, Ang, Jann C, Clare, Rumi, Ivetic, Nikola, Chetty, Vasudhevan T, Bowdish, Dawn M E, Miller, Matthew S, Kelton, John G, Nazy, Ishac

“…Coronavirus Disease 2019 (COVID-19) is a global pandemic caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). While detection of…”
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A platelet viability assay (PVA) for the diagnosis of heparin-induced thrombocytopenia by Ivetic, Nikola, Arnold, Donald M., Smith, James W., Huynh, Angela, Kelton, John G., Nazy, Ishac

“…Diagnosing heparin-induced thrombocytopenia (HIT) requires functional assays measuring platelet activation as they are highly specific and sensitive. A useful…”
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Lasting Changes to Circulating Leukocytes in People with Mild SARS-CoV-2 Infections by Kennedy, Allison E, Cook, Laura, Breznik, Jessica A, Cowbrough, Braeden, Wallace, Jessica G, Huynh, Angela, Smith, James W, Son, Kiho, Stacey, Hannah, Ang, Jann, McGeer, Allison, Coleman, Brenda L, Larché, Maggie, Larché, Mark, Hambly, Nathan, Nair, Parameswaran, Ask, Kjetil, Miller, Matthew S, Bramson, Jonathan, Levings, Megan K, Nazy, Ishac, Svenningsen, Sarah, Mukherjee, Manali, Bowdish, Dawn M E

“…Survivors of severe SARS-CoV-2 infections frequently suffer from a range of post-infection sequelae. Whether survivors of mild or asymptomatic infections can…”
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Discovery of a Novel Polymer for Human Pluripotent Stem Cell Expansion and Multilineage Differentiation by Celiz, Adam D., Smith, James G. W., Patel, Asha K., Hook, Andrew L., Rajamohan, Divya, George, Vinoj T., Flatt, Luke, Patel, Minal J., Epa, Vidana C., Singh, Taranjit, Langer, Robert, Anderson, Daniel G., Allen, Nicholas D., Hay, David C., Winkler, David A., Barrett, David A., Davies, Martyn C., Young, Lorraine E., Denning, Chris, Alexander, Morgan R.

“…A scalable and cost‐effective synthetic polymer substrate that supports robust expansion and subsequent multilineage differentiation of human pluripotent stem…”
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Molecular architecture and platelet-activating properties of small immune complexes assembled on heparin and platelet factor 4 by Yang, Yang, Du, Yi, Ivanov, Daniil, Niu, Chendi, Clare, Rumi, Smith, James W., Nazy, Ishac, Kaltashov, Igor A.

“…Heparin-induced thrombocytopenia (HIT) is an adverse reaction to heparin leading to a reduction in circulating platelets with an increased risk of thrombosis…”
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Development of a high-yield expression and purification system for platelet factor 4 by Huynh, Angela, Arnold, Donald M, Moore, Jane C, Smith, James W, Kelton, John G, Nazy, Ishac

“…Heparin-induced thrombocytopenia (HIT) is an adverse drug reaction characterized by IgG antibodies bound to complexes of platelet factor 4 (PF4) and heparin…”
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Producing megakaryocytes from a human peripheral blood source by Ivetic, Nikola, Nazi, Ishac, Karim, Nadia, Clare, Rumi, Smith, James W., Moore, Jane C., Hope, Kristin J., Kelton, John G., Arnold, Donald M.

“…BACKGROUND Cultured megakaryocytes could prove useful in the study of human diseases, but it is difficult to produce sufficient numbers for study. We describe…”
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High‐dose IVIG plus cangrelor platelet “anesthesia” during urgent heparin‐CPB in a patient with recent SRA‐negative HIT‐thrombosis with persisting platelet‐activating antibodies by Koster, Andreas, Nazy, Ishac, Birschmann, Ingvild E., Smith, James W., Sheppard, Jo‐Ann I., Warkentin, Theodore E.

“…In a high‐risk patient with subacute heparin‐induced thrombocytopenia (HIT) type A (platelet count recovery following acute HIT but with persisting…”
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ROS-mediated PI3K activation drives mitochondrial transfer from stromal cells to hematopoietic stem cells in response to infection by Mistry, Jayna J., Marlein, Christopher R., Moore, Jamie A., Hellmich, Charlotte, Wojtowicz, Edyta E., Smith, James G. W., Macaulay, Iain, Sun, Yu, Morfakis, Adam, Patterson, Angela, Horton, Rebecca H., Divekar, Devina, Morris, Christopher J., Haestier, Anna, Di Palma, Federica, Beraza, Naiara, Bowles, Kristian M., Rushworth, Stuart A.

“…Hematopoietic stem cells (HSCs) undergo rapid expansion in response to stress stimuli. Here we investigate the bioenergetic processes which facilitate the HSC…”
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Platelet‐activating immune complexes identified in critically ill COVID‐19 patients suspected of heparin‐induced thrombocytopenia by Nazy, Ishac, Jevtic, Stefan D., Moore, Jane C., Huynh, Angela, Smith, James W., Kelton, John G., Arnold, Donald M.

“…Background Thrombocytopenia and thrombosis are prominent in coronavirus disease 2019 (COVID‐19), particularly among critically ill patients; however, the…”
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Adjunct Immune Globulin for Vaccine-Induced Immune Thrombotic Thrombocytopenia by Bourguignon, Alex, Arnold, Donald M, Warkentin, Theodore E, Smith, James W, Pannu, Tania, Shrum, Jeffrey M, Al Maqrashi, Zainab A.A, Shroff, Anjali, Lessard, Marie-Claude, Blais, Normand, Kelton, John G, Nazy, Ishac

“…The use of high-dose intravenous immune globulin (IVIG) plus anticoagulation is recommended for the treatment of vaccine-induced immune thrombotic…”
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Increased All-Cause and Cancer Mortality in HTLV-II Infection by BISWAS, Hope H, KAIDAROVA, Zhanna, GARRATTY, George, GIBBLE, Joan W, NEWMAN, Bruce H, SMITH, James W, ZIMAN, Alyssa, FRIDEY, Joy L, SACHER, Ronald A, MURPHY, Edward L

“…Human T-lymphotropic virus (HTLV)-I and HTLV-II cause chronic human retroviral infections, but few studies have examined the impact of either virus on survival…”
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Experiments on horizontal mergers: Does size matter? by Beckman, Steven R., DeAngelo, Gregory, James Smith, W.

“…Current Department of Justice merger guidelines assume that merging the capacities of two firms will translate into an equivalent increase in market shares…”
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Materials for stem cell factories of the future by Celiz, Adam D., Smith, James G. W., Langer, Robert, Anderson, Daniel G., Winkler, David A., Barrett, David A., Davies, Martyn C., Young, Lorraine E., Denning, Chris, Alexander, Morgan R.

“…Human pluripotent stem cells (hPSCs) have great potential for regenerative medicine, yet producing billions of hPSCs suitable for clinical use needs defined…”
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Therapeutic apheresis: a summary of current indication categories endorsed by the AABB and the American Society for Apheresis by Smith, James W., Weinstein, Robert, For The AABB Hemapheresis Committee, Krista L. Hillyer

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