Search Results - "Smith, Jake L. R."

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  1. 1

    Cryo-plasma FIB/SEM volume imaging of biological specimens by Dumoux, Maud, Glen, Thomas, Smith, Jake L R, Ho, Elaine M L, Perdigão, Luis M A, Pennington, Avery, Klumpe, Sven, Yee, Neville B Y, Farmer, David Andrew, Lai, Pui Y A, Bowles, William, Kelley, Ron, Plitzko, Jürgen M, Wu, Liang, Basham, Mark, Clare, Daniel K, Siebert, C Alistair, Darrow, Michele C, Naismith, James H, Grange, Michael

    Published in eLife (21-02-2023)
    “…Serial focussed ion beam scanning electron microscopy (FIB/SEM) enables imaging and assessment of subcellular structures on the mesoscale (10 nm to 10 µm)…”
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    Journal Article
  2. 2

    Ot2Rec: A semi-automatic, extensible, multi-software tomographic reconstruction workflow by Yee, Neville B-Y, Ho, Elaine M L, Tun, Win, Smith, Jake L R, Dumoux, Maud, Grange, Michael, Darrow, Michele C, Basham, Mark

    “…Electron cryo-tomography is an imaging technique for probing 3D structures with at the nanometer scale. This technique has been used extensively in the…”
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    Journal Article
  3. 3

    The Mechanism of SARS-CoV-2 Nucleocapsid Protein Recognition by the Human 14-3-3 Proteins by Tugaeva, Kristina V., Hawkins, Dorothy E.D.P., Smith, Jake L.R., Bayfield, Oliver W., Ker, De-Sheng, Sysoev, Andrey A., Klychnikov, Oleg I., Antson, Alfred A., Sluchanko, Nikolai N.

    Published in Journal of molecular biology (16-04-2021)
    “…[Display omitted] •SARS-CoV-2 nucleocapsid protein (N) binds to all seven human 14-3-3 isoforms.•This association with 14-3-3 strictly depends on…”
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    Journal Article
  4. 4

    Structural atlas of a human gut crassvirus by Bayfield, Oliver W., Shkoporov, Andrey N., Yutin, Natalya, Khokhlova, Ekaterina V., Smith, Jake L. R., Hawkins, Dorothy E. D. P., Koonin, Eugene V., Hill, Colin, Antson, Alfred A.

    Published in Nature (London) (11-05-2023)
    “…CrAssphage and related viruses of the order Crassvirales (hereafter referred to as crassviruses) were originally discovered by cross-assembly of metagenomic…”
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    Journal Article
  5. 5

    Human 14-3-3 Proteins Site-selectively Bind the Mutational Hotspot Region of SARS-CoV-2 Nucleoprotein Modulating its Phosphoregulation by Tugaeva, Kristina V., Sysoev, Andrey A., Kapitonova, Anna A., Smith, Jake L.R., Zhu, Phillip, Cooley, Richard B., Antson, Alfred A., Sluchanko, Nikolai N.

    Published in Journal of molecular biology (30-01-2023)
    “…[Display omitted] •S197 and T205 are mutually exclusive 14-3-3-binding phosphosites in SARS-CoV-2 N.•T205 is the preferred binding site by all seven human…”
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  6. 6

    The DNA polymerase of bacteriophage YerA41 replicates its T-modified DNA in a primer-independent manner by Gomez-Raya-Vilanova, Miguel V, Leskinen, Katarzyna, Bhattacharjee, Arnab, Virta, Pasi, Rosenqvist, Petja, Smith, Jake L R, Bayfield, Oliver W, Homberger, Christina, Kerrinnes, Tobias, Vogel, Jörg, Pajunen, Maria I, Skurnik, Mikael

    Published in Nucleic acids research (22-04-2022)
    “…Abstract Yersinia phage YerA41 is morphologically similar to jumbo bacteriophages. The isolated genomic material of YerA41 could not be digested by restriction…”
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  7. 7

    A protocol for cryogenic volumetric imaging using serial plasma FIB/SEM by Dumoux, Maud, Smith, Jake L R, Glen, Thomas, Grange, Michael, Darrow, Michele C, Naismith, James H

    Published in Methods in cell biology (2023)
    “…Cryogenic volumetric imaging using serial plasma focused ion beam scanning electron microscopy (serial pFIB/SEM) is a new and exciting correlative volume…”
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    Journal Article